Development Level

Tbio 32 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

decreased circulating serum al... 2 | 82
decreased exploration in new e... 2 | 11
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
mydriasis 1 | 6
pallor 1 | 34
small adrenal glands 1 | 16
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

psoriasis 29 | 6,694
Carcinoma 25 | 11,493
osteosarcoma 20 | 7,950
ovarian cancer 20 | 8,520
glioblastoma 17 | 5,792
diabetes mellitus 16 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
invasive ductal carcinoma 16 | 2,951
Breast cancer 15 | 3,578
ductal carcinoma in situ 15 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung cancer 15 | 4,740
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
malignant mesothelioma 14 | 3,232
medulloblastoma, large-cell 14 | 6,241
Cancer 13 | 2,499
non-small cell lung cancer 13 | 2,890
Obesity 12 | 678
ependymoma 12 | 4,679
lung adenocarcinoma 12 | 2,716
lung carcinoma 12 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Atherosclerosis 11 | 291
Autosomal recessive predisposition 11 | 1,442
Astrocytoma, Pilocytic 10 | 3,081
Coronary artery disease 10 | 268
Lipid metabolism disorder 10 | 114
group 3 medulloblastoma 10 | 4,104
primitive neuroectodermal tumor 10 | 3,035
Kidney cancer 9 | 2,613
Schizophrenia 9 | 1,160
pancreatic cancer 9 | 2,398
Atopic dermatitis 8 | 952
active ulcerative colitis 8 | 764
adult high grade glioma 8 | 3,801
cystic fibrosis 8 | 1,696
pituitary cancer 8 | 1,972
Hypercholesterolemia, Familial 7 | 23
Hyperlipoproteinemia Type II 7 | 12
Hypertension 7 | 396
Kidney disease 7 | 430
interstitial cystitis 7 | 2,312
Alzheimer's disease 6 | 658
Simpson-Golabi-Behmel syndrome 6 | 19
Splenomegaly 6 | 190
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
fibroadenoma 6 | 559
group 4 medulloblastoma 6 | 1,855
nasopharyngeal carcinoma 6 | 1,058
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
Amyloidosis 5 | 67
Broad flat nasal bridge 5 | 236
Cardiovascular system disease 5 | 246
Cerebrovascular disease 5 | 238
Chemical and Drug Induced Liver Injury 5 | 195
Hepatomegaly 5 | 285
Hypercholesterolemia 5 | 44
Hyperlipidemia 5 | 43
Hypertensive disease 5 | 292
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Myocardial Infarction 5 | 151
Nasal bridge wide 5 | 236
Pancreatitis 5 | 123
Polycystic ovary syndrome 5 | 360
Serum cholesterol raised 5 | 22
Umbilical hernia 5 | 93
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
nephrosclerosis 5 | 333
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Alcoholic Intoxication, Chronic 4 | 289
Arcus Senilis 4 | 11
Atrial Septal Defects 4 | 85
Cardiomyopathies 4 | 110
Cardiovascular Diseases 4 | 59
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Drug Eruptions 4 | 18
Duchenne muscular dystrophy 4 | 601
Heart disease 4 | 306
Large intestine cancer 4 | 126
Liver cancer 4 | 604
Lung Neoplasms 4 | 232
Short nose 4 | 132
Small nose 4 | 132
Stomach Neoplasms 4 | 300
Vascular disease 4 | 319
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
hearing impairment 4 | 199
posterior fossa group B ependymoma 4 | 416

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Blood and immune system 40 | 16,909
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 14 | 4,145

Reactome Pathway

Retinoid metabolism and transp... 43 | 43
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta,beta-carotene 9',10'-oxygenase BCO2 Tbio Enzyme -1.64030 46.1 93
Retinol-binding protein 2 RBP2 Tbio Non-IDG -2.08995 120.9 150
Low-density lipoprotein receptor-related protein 12 LRP12 Tbio Non-IDG -0.57984 4.31 145
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
All-trans-retinol 13,14-reductase RETSAT Tbio Enzyme -0.76918 7.46 14
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Low-density lipoprotein receptor-related protein 10 LRP10 Tdark Non-IDG -0.59529 3.83 84
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Retinol-binding protein 1 RBP1 Tbio Non-IDG -2.65868 476.2 195
Low-density lipoprotein receptor-related protein 8 LRP8 Tbio Non-IDG -2.17223 148.7 283