Development Level

Tbio 6 | 11,178
Tchem 1 | 1,885

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal liver morphology 1 | 17
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
decreased IgE level 1 | 6
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

Carcinoma 3 | 11,192
Cryptorchidism 3 | 287
Kidney cancer 2 | 2,548
ependymoma 2 | 4,559
Alzheimer's disease 1 | 640
Astrocytoma, Pilocytic 1 | 3,006
Chromosome 9p deletion syndrome 1 | 13
Endometrial cancer 1 | 301
Endometriosis 1 | 521
Hyperplasia 1 | 26
Infertility 1 | 176
Myocardial Ischemia 1 | 162
Peripartum cardiomyopathy 1 | 4
Pick disease 1 | 1,856
Prostatic Neoplasms 1 | 472
Testicular cancer 1 | 25
Tick infestation 1 | 17
adrenocortical adenoma 1 | 127
adrenocortical carcinoma 1 | 1,385
adult high grade glioma 1 | 3,701
astrocytic glioma 1 | 2,530
atypical teratoid / rhabdoid tumor 1 | 4,971
glioblastoma 1 | 5,635
group 3 medulloblastoma 1 | 4,002
lung adenocarcinoma 1 | 2,627
lung cancer 1 | 4,607
lung carcinoma 1 | 2,755
medulloblastoma, large-cell 1 | 6,086
non-small cell lung cancer 1 | 2,799
oligodendroglioma 1 | 2,768
osteosarcoma 1 | 7,766
primitive neuroectodermal tumor 1 | 2,957
psoriasis 1 | 6,514
tuberculosis and treatment for 3 months 1 | 175

Tissue

Endocrine System 6 | 18,159
Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Liver and Pancreas 3 | 16,750
Nervous System 3 | 16,725
Cardiovascular System 2 | 15,192

Target Family

GPCR 4 | 408
Non-IDG 3 | 12,091

Reactome Pathway

Relaxin receptors 7 | 7
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin-3 receptor 1 RXFP3 Tchem GPCR -1.66523 53.0 181
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Insulin-like peptide INSL5 INSL5 Tbio Non-IDG -1.42311 26.9 46
Relaxin receptor 1 RXFP1 Tbio GPCR -2.21377 176.7 266
Relaxin-3 receptor 2 RXFP4 Tbio GPCR -1.21798 15.6 115
Prorelaxin H2 RLN2 Tbio Non-IDG -2.02045 98.4 230