Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
decreased bone mineral density 1 | 126
impaired glucose tolerance 1 | 75
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
diabetes mellitus 4 | 1,728
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
maturity-onset diabetes of the young 3 | 32
Cancer 2 | 2,499
Cholestasis 2 | 155
Diabetes Mellitus, Experimental 2 | 108
Glycosuria 2 | 29
Hyperglycemia 2 | 137
Kidney disease 2 | 430
PANCREATIC AGENESIS 1 2 | 2
Pancreatic Agenesis, Congenital 2 | 2
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pancreatic agenesis 2 | 17
lung cancer 2 | 4,740
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
Acquired metabolic disease 1 | 336
Anovulation 1 | 21
Arthritis, Gouty 1 | 9
Arthrogryposis 1 | 54
Autosomal dominant polycystic kidney disease 1 | 31
Autosomal recessive polycystic kidney disease 1 | 41
Axial hypotonia 1 | 46
BILIARY TRACT ABNORMALITY 1 | 16
Bilateral ptosis 1 | 9
Biliary Tract Diseases 1 | 16
Blepharoptosis 1 | 231
Carcinoma, Renal Cell 1 | 124
Cerebellar Diseases 1 | 6
Chemical and Drug Induced Liver Injury 1 | 195
Chromosome 17q12 deletion syndrome 1 | 16
Chronic kidney disease stage 5 1 | 31
Congenital Heart Defects 1 | 58
Congenital ear anomaly NOS (disorder) 1 | 29
Congenital heart disease 1 | 93
Contracture of lower limb 1 | 6
Dehydration 1 | 40
Dental caries 1 | 164
Developmental coordination disorder 1 | 8
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Downturned corners of mouth 1 | 48
Dracunculiasis 1 | 6
Echinococcosis 1 | 26
Epilepsies, Myoclonic 1 | 32
Exocrine pancreatic insufficiency 1 | 32
Female infertility 1 | 30
Fibrosarcoma 1 | 14
Frontotemporal dementia 1 | 51
Generalized myoclonic seizures 1 | 30
Gout 1 | 106
High urine albumin levels 1 | 5
Hypomagnesemia 2, renal 1 | 4
Hypovolemia 1 | 8
Hypsarrhythmia 1 | 25
Impaired glucose tolerance 1 | 28
Infertility, Female 1 | 28
Insulin Resistance 1 | 72
Insulinoma 1 | 24
Ketoacidosis 1 | 11
Ketonuria 1 | 8
Leydig cell tumor 1 | 9
Limb contractures 1 | 6
Loiasis 1 | 5
Low Birth Weights 1 | 69
Malignant tumor of prostate 1 | 26
Maturity onset diabetes mellitus in young 1 | 11
Microalbuminuria 1 | 5
Multicystic renal dysplasia, bilateral 1 | 2
Muscle Weakness 1 | 170
Myoclonic Epilepsies, Progressive 1 | 44
No development of motor milestones 1 | 147
Obstruction of pelviureteric junction 1 | 8
Onchocerciasis 1 | 10
Osteoporosis 1 | 363
Pancreatic Insufficiency 1 | 13
Pancreatitis 1 | 123
Penile hypospadias 1 | 106
Peripheral Neuropathy 1 | 134
Prominent metopic ridge 1 | 15
Prostate cancer, familial 1 | 13
Pulmonary venoocclusive disease 1 | 3
Reduced pancreatic beta cells 1 | 6
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Renal cysts and diabetes syndrome 1 | 2
Retinal Diseases 1 | 55
Serum creatinine raised 1 | 7
Small for gestational age (disorder) 1 | 69
Spermatocele 1 | 4
Tonic - clonic seizures 1 | 44
VACTERL association 1 | 26
Weight decreased 1 | 103
blepharophimosis, ptosis, and epicanthus inversus syndrome 1 | 8
permanent neonatal diabetes mellitus 1 | 9
renal hypomagnesemia 2 1 | 2

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Liver and Pancreas 7 | 16,750
Nervous System 6 | 16,725
Female tissues 5 | 17,400
Skin and soft tissues 5 | 17,230
Male tissues 4 | 17,142
Blood and immune system 3 | 16,909
Urinary Tract 3 | 16,678
Cardiovascular System 2 | 15,192
Respiratory system 2 | 16,393

Target Family

Transcription Factor 6 | 1,400
Nuclear Receptor 1 | 48

Reactome Pathway

Regulation of gene expression ... 7 | 7
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pancreas transcription factor 1 subunit alpha PTF1A Tbio Transcription Factor -2.60800 401.4 317
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
One cut domain family member 3 ONECUT3 Tbio Transcription Factor -1.90980 77.6 118
Hepatocyte nuclear factor 1-beta HNF1B Tbio Transcription Factor -2.63510 401.5 403
Homeobox protein Nkx-6.1 NKX6-1 Tbio Transcription Factor -1.86592 62.8 247
Nuclear receptor subfamily 5 group A member 2 NR5A2 Tchem Nuclear Receptor -2.49333 323.5 303
Hepatocyte nuclear factor 6 ONECUT1 Tbio Transcription Factor -1.90702 90.1 126