Development Level

Tbio 13 | 10,625
Tchem 4 | 1,890
Tclin 4 | 602
Tdark 3 | 7,003

IMPC Term

abnormal coping response 1 | 12
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

Cancer 13 | 2,346
osteosarcoma 10 | 7,933
ovarian cancer 9 | 8,484
Hepatitis C 8 | 90
medulloblastoma, large-cell 8 | 6,234
psoriasis 8 | 6,685
glioblastoma 6 | 5,572
lung cancer 6 | 4,466
Hepatitis B 5 | 103
Multiple Sclerosis 5 | 498
Rheumatoid Arthritis 5 | 1,160
atypical teratoid / rhabdoid tumor 5 | 4,369
pancreatic cancer 5 | 2,300
Carcinoma 4 | 2,147
Hepatitis 4 | 61
Influenza 4 | 142
Multiple myeloma 4 | 1,327
cutaneous lupus erythematosus 4 | 1,056
ependymoma 4 | 2,514
group 4 medulloblastoma 4 | 1,875
malignant mesothelioma 4 | 3,162
pancreatic carcinoma 4 | 567
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Down syndrome 3 | 548
Hypersensitivity reaction type II disease 3 | 235
Melanoma 3 | 261
Pick disease 3 | 1,893
Polycythemia Vera 3 | 24
astrocytoma 3 | 1,493
dermatomyositis 3 | 933
diabetes mellitus 3 | 1,663
juvenile dermatomyositis 3 | 1,189
non-small cell lung cancer 3 | 2,798
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
Anemia 2 | 252
Asthma 2 | 349
Breast cancer 2 | 3,094
Chronic hepatitis C 2 | 12
Chronic type B viral hepatitis 2 | 2
Crohn Disease 2 | 97
Crohn's disease 2 | 304
Encephalitis 2 | 54
Gaucher disease type 1 2 | 171
Hepatitis D 2 | 10
Hodgkin Disease 2 | 16
Inflammatory bowel disease 2 | 142
Leukopenia 2 | 42
Liver Cirrhosis 2 | 101
Liver Cirrhosis, Experimental 2 | 108
Liver carcinoma 2 | 217
Liver disease 2 | 219
Liver diseases 2 | 66
Metabolic syndrome X 2 | 155
Muscle Weakness 2 | 92
Myocarditis 2 | 17
Neuroblastoma 2 | 78
Obesity 2 | 616
Pancreatic Neoplasm 2 | 79
Relapsing remitting multiple sclerosis 2 | 14
Renal Cell Carcinoma 2 | 199
Severe acute respiratory syndrome 2 | 26
Thrombocytopenia 2 | 105
Vascular disease 2 | 281
active Crohn's disease 2 | 918
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,665
gastric carcinoma 2 | 832
head and neck cancer 2 | 270
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
lung carcinoma 2 | 2,844
nasopharyngeal carcinoma 2 | 1,056
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674
systemic lupus erythematosus 2 | 156
tuberculosis and treatment for 3 months 2 | 327
Cortical blindness 1 | 15
Hyperglycemia 1 | 120
Hypertrophic Cardiomyopathy 1 | 56
Leiomyosarcoma 1 | 19
Liver Neoplasms, Experimental 1 | 48
Lymphoid leukemia 1 | 69
Myocardial Infarction 1 | 126
Neurofibromatosis 1 | 37
Ollier disease 1 | 15
Pain 1 | 70
Stuttering 1 | 18
Type 1 diabetes mellitus 1 | 101

Tissue

Nervous System 24 | 18,561
Digestive Tract 22 | 18,473
Female tissues 22 | 18,647
Urinary Tract 22 | 18,444
Skin and soft tissues 21 | 18,115
Blood and immune system 18 | 17,995
Endocrine System 18 | 18,512
Cardiovascular System 17 | 17,958
Liver and Pancreas 17 | 18,136
Respiratory system 15 | 17,484
Male tissues 13 | 17,969

Target Family

Non-IDG 16 | 11,971
Enzyme 4 | 4,146
Kinase 2 | 634
Transcription Factor 2 | 1,400

Reactome Pathway

Regulation of IFNA signaling 24 | 24
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.87993 74.0 225
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.00271 1072.1 392
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.06784 1308.8 971
Interferon alpha-7 IFNA7 Tdark Non-IDG -0.67991 3.90 46
Interferon alpha-10 IFNA10 Tbio Non-IDG -1.24816 16.2 115
Interferon alpha-2 IFNA2 Tbio Non-IDG -3.37730 2309.7 710
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39525 239.8 41
Interferon alpha-14 IFNA14 Tdark Non-IDG -0.37144 2.01 45
Interferon alpha-5 IFNA5 Tbio Non-IDG -1.76173 51.4 127
Interferon alpha-21 IFNA21 Tbio Non-IDG -0.86132 5.76 74