Development Level

Tbio 13 | 10,625
Tchem 4 | 1,890
Tclin 4 | 602
Tdark 3 | 7,003

IMPC Phenotype

abnormal coping response 1 | 12
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

Cancer 13 | 2,346
osteosarcoma 10 | 7,933
ovarian cancer 9 | 8,491
Hepatitis C 8 | 90
medulloblastoma, large-cell 8 | 6,234
psoriasis 8 | 6,685
glioblastoma 6 | 5,572
lung cancer 6 | 4,473
Hepatitis B 5 | 103
Multiple Sclerosis 5 | 498
Rheumatoid Arthritis 5 | 1,170
atypical teratoid / rhabdoid tumor 5 | 4,369
pancreatic cancer 5 | 2,300
Carcinoma 4 | 2,147
Hepatitis 4 | 61
Influenza 4 | 142
Multiple myeloma 4 | 1,327
cutaneous lupus erythematosus 4 | 1,056
ependymoma 4 | 2,514
group 4 medulloblastoma 4 | 1,875
malignant mesothelioma 4 | 3,163
pancreatic carcinoma 4 | 567
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Down syndrome 3 | 548
Hypersensitivity reaction type II disease 3 | 235
Melanoma 3 | 261
Pick disease 3 | 1,893
Polycythemia Vera 3 | 24
astrocytoma 3 | 1,493
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,663
juvenile dermatomyositis 3 | 1,189
non-small cell lung cancer 3 | 2,798
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Anemia 2 | 252
Asthma 2 | 349
Breast cancer 2 | 3,098
Chronic hepatitis C 2 | 12
Chronic type B viral hepatitis 2 | 2
Crohn Disease 2 | 97
Crohn's disease 2 | 304
Encephalitis 2 | 54
Gaucher disease type 1 2 | 171
Hepatitis D 2 | 10
Hodgkin Disease 2 | 16
Inflammatory bowel disease 2 | 142
Leukopenia 2 | 42
Liver Cirrhosis 2 | 101
Liver Cirrhosis, Experimental 2 | 108
Liver carcinoma 2 | 217
Liver disease 2 | 219
Liver diseases 2 | 66
Metabolic syndrome X 2 | 155
Muscle Weakness 2 | 92
Myocarditis 2 | 17
Neuroblastoma 2 | 78
Obesity 2 | 616
Pancreatic Neoplasm 2 | 79
Relapsing remitting multiple sclerosis 2 | 14
Renal Cell Carcinoma 2 | 199
Severe acute respiratory syndrome 2 | 26
Thrombocytopenia 2 | 105
Vascular disease 2 | 281
active Crohn's disease 2 | 918
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,670
gastric carcinoma 2 | 832
head and neck cancer 2 | 270
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,714
lung carcinoma 2 | 2,844
nasopharyngeal carcinoma 2 | 1,056
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
primary Sjogren syndrome 2 | 788
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674
systemic lupus erythematosus 2 | 172
tuberculosis and treatment for 3 months 2 | 327
Achondroplasia 1 | 20
Aicardi-Goutieres syndrome 1 | 18
Avian influenza 1 | 8
Biliary cirrhosis 1 | 33
Crimean-Congo hemorrhagic fever 1 | 10
Herpes simplex 1 | 19
Insulin Resistance 1 | 50
Myelitis 1 | 8
Peyronie's disease 1 | 8
Retinal Diseases 1 | 21
Stomatitis 1 | 19
Thanatophoric dysplasia 1 | 5

Tissue

Nervous System 24 | 18,560
Digestive Tract 22 | 18,472
Female tissues 22 | 18,646
Urinary Tract 22 | 18,443
Skin and soft tissues 21 | 18,114
Blood and immune system 18 | 17,994
Endocrine System 18 | 18,511
Cardiovascular System 17 | 17,957
Liver and Pancreas 17 | 18,135
Respiratory system 15 | 17,483
Male tissues 13 | 17,968

Target Family

Non-IDG 16 | 11,969
Enzyme 4 | 4,146
Kinase 2 | 634
Transcription Factor 2 | 1,400

Reactome Pathway

Regulation of IFNA signaling 24 | 24
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubl carboxyl-terminal hydrolase 18 USP18 Tbio Enzyme -1.77723 68.2 69
Signal transducer and activator of transcription 1-alpha/beta STAT1 Tchem Transcription Factor -3.29893 1889.3 1357
Interferon alpha-8 IFNA8 Tbio Non-IDG -1.38242 22.0 54
Interferon alpha/beta receptor 1 IFNAR1 Tclin Non-IDG -2.61876 407.4 484
Tyrosine-protein kinase JAK1 JAK1 Tclin Kinase -2.73793 446.6 400
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.02347 1072.1 392
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.08398 1308.8 971
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.90656 74.0 225
Suppressor of cytokine signaling 3 SOCS3 Tbio Non-IDG -3.02865 1085.7 446
Interferon beta IFNB1 Tbio Non-IDG -3.81999 6507.5 587