Development Level

Tbio 23 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602

IMPC Term

increased circulating sodium l... 2 | 71
cardiovascular system phenotyp... 1 | 35
decreased heart rate variabili... 1 | 11
decreased prepulse inhibition 1 | 52
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
shortened RR interval 1 | 19
thrombocytopenia 1 | 46

Disease

ovarian cancer 15 | 8,484
lung cancer 13 | 4,466
lung carcinoma 13 | 2,844
non-small cell lung cancer 12 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Complement deficiency 10 | 15
malignant mesothelioma 10 | 3,162
Age related macular degeneration 9 | 84
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung adenocarcinoma 9 | 2,713
psoriasis 9 | 6,685
Cancer 8 | 2,346
glioblastoma 8 | 5,572
invasive ductal carcinoma 8 | 2,950
pilocytic astrocytoma 8 | 3,086
ulcerative colitis 8 | 2,087
Anemia 7 | 252
Kidney disease 7 | 396
Vascular disease 7 | 281
hemolytic-uremic syndrome 7 | 28
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
osteosarcoma 7 | 7,933
Atypical Hemolytic Uremic Syndrome 6 | 9
Immunologic Deficiency Syndromes 6 | 16
Rheumatoid Arthritis 6 | 1,160
dermatomyositis 6 | 933
mucosa-associated lymphoid tissue lymphoma 6 | 480
pancreatic cancer 6 | 2,300
subependymal giant cell astrocytoma 6 | 2,287
Carcinoma 5 | 2,147
IGA Glomerulonephritis 5 | 454
Macular degeneration 5 | 41
Meningitis 5 | 46
adrenocortical carcinoma 5 | 1,427
Breast cancer 4 | 3,094
Thrombocytopenia 4 | 105
Type 1 diabetes mellitus 4 | 101
active Crohn's disease 4 | 918
astrocytoma 4 | 1,493
atypical teratoid / rhabdoid tumor 4 | 4,369
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
gastric carcinoma 4 | 832
group 4 medulloblastoma 4 | 1,875
medulloblastoma, large-cell 4 | 6,234
oligodendroglioma 4 | 2,849
posterior fossa group A ependymoma 4 | 1,511
systemic lupus erythematosus 4 | 156
tuberculosis 4 | 1,557
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Congenital afibrinogenemia 3 | 9
Down syndrome 3 | 548
Duchenne muscular dystrophy 3 | 602
Macular Degeneration, Age-Related, 1 3 | 9
Multiple Sclerosis 3 | 498
Protein S deficiency 3 | 5
Thrombotic thrombocytopenic purpura 3 | 14
cystic fibrosis 3 | 1,665
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 291
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 789
Barrett's esophagus 2 | 183
Becker muscular dystrophy 2 | 187
Congenital adrenal hyperplasia 2 | 74
Hypermobility syndrome 2 | 17
Immunoglobulin alpha deficiency 2 | 10
Juvenile arthritis 2 | 124
Lupus Erythematosus, Systemic 2 | 73
Malaria 2 | 140
Multiple myeloma 2 | 1,327
Myasthenia Gravis 2 | 26
Pick disease 2 | 1,893
Proteinuria 2 | 63
Relapsing fever 2 | 16
Skin disease 2 | 65
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
axial spondyloarthropathy 2 | 28
chronic lymphosyte leukemia 2 | 232
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 532
juvenile dermatomyositis 2 | 1,189
limb girdle muscular dystrophy 2A 2 | 156
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
pediatric high grade glioma 2 | 2,712
periodontitis 2 | 269
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 26 | 17,995
Cardiovascular System 26 | 17,958
Digestive Tract 26 | 18,473
Endocrine System 26 | 18,512
Female tissues 26 | 18,647
Liver and Pancreas 26 | 18,136
Male tissues 26 | 17,969
Nervous System 26 | 18,561
Respiratory system 26 | 17,484
Skin and soft tissues 26 | 18,115
Urinary Tract 26 | 18,444

Target Family

Non-IDG 22 | 11,971
GPCR 3 | 406
Transcription Factor 1 | 1,400

Reactome Pathway

Regulation of Complement casca... 26 | 26
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement component C9 C9 Tbio Non-IDG -1.85517 71.0 229
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739
Complement component C6 C6 Tbio Non-IDG -1.53803 35.0 124
Membrane cofactor protein CD46 Tbio Non-IDG -2.90635 849.0 564
Complement receptor type 1 CR1 Tbio Non-IDG -3.33619 2279.9 502
Complement C3 C3 Tbio Non-IDG -3.53414 3337.1 965
Complement C5 C5 Tclin Non-IDG -2.19589 154.9 317
Complement factor H-related protein 3 CFHR3 Tbio Non-IDG -1.46549 27.8 22
Complement factor B CFB Tbio Non-IDG -2.83644 695.7 426
Complement factor H CFH Tbio Non-IDG -3.10970 1330.3 512