Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 2 | 298
abnormal femur morphology 1 | 14
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased total retina thickne... 1 | 17
hypoactivity 1 | 132
increased circulating glycerol... 1 | 9
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Cancer 6 | 2,499
ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 4 | 7,950
Carcinoma, Squamous Cell 3 | 110
Skin Neoplasms 3 | 69
Squamous cell carcinoma 3 | 129
Vascular disease 3 | 319
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
psoriasis 3 | 6,694
Adult T-Cell Lymphoma/Leukemia 2 | 30
Astrocytoma, Pilocytic 2 | 3,081
Chemical and Drug Induced Liver Injury 2 | 195
Leukemia-Lymphoma, Adult T-Cell 2 | 30
Renal Cell Carcinoma 2 | 214
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Agammaglobulinemia 1 | 34
Anemia 1 | 365
Arthritis 1 | 290
Atopic dermatitis 1 | 952
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Autosomal recessive polycystic kidney disease 1 | 41
Bladder Neoplasm 1 | 112
Blastic phase chronic myeloid leukemia 1 | 58
Breast Neoplasms 1 | 445
Breast cancer 1 | 3,578
COPD 1 | 118
Carcinoma of colon 1 | 32
Cardiomegaly 1 | 116
Central sleep apnea 1 | 11
Cherubism 1 | 13
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Colitis 1 | 54
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Connective tissue disease 1 | 62
Early myoclonic encephalopathy 1 | 15
Gastrointestinal stromal tumor 1 | 62
Gastrointestinal system disease 1 | 54
Heart disease 1 | 306
Hemolytic anemia 1 | 77
Hepatomegaly 1 | 285
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Increased gastric cancer 1 | 21
Intellectual disability 1 | 1,016
Kidney cancer 1 | 2,613
Kidney disease 1 | 430
Leber congenital amaurosis 6 1 | 2
Leiomyosarcoma of uterus 1 | 13
Lethargy 1 | 77
Liver Cirrhosis, Experimental 1 | 769
Lymphopenia 1 | 67
Lymphoproliferative syndrome 1 | 58
Mammary Neoplasms 1 | 425
Multiple myeloma 1 | 1,332
Necrosis 1 | 53
Neoplasm Invasiveness 1 | 161
Neurodegenerative disease 1 | 414
Noonan syndrome 1 | 34
Osteopetrosis 1 | 43
Osteoporosis 1 | 363
Ovarian Neoplasms 1 | 102
Pancreatic Neuroendocrine Tumor 1 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pick disease 1 | 1,894
Polycystic Kidney, Autosomal Recessive 1 | 9
Rheumatoid arthritis 1 | 1,191
Status Epilepticus 1 | 98
Stomach Neoplasms 1 | 300
Systemic lupus erythematosus 1 | 194
THROMBOCYTOPENIA 6 1 | 1
Transitional cell carcinoma of bladder 1 | 17
Urinary Bladder Neoplasms 1 | 114
Urinary bladder cancer 1 | 36
Vici syndrome 1 | 14
Weight Loss 1 | 24
Weight decreased 1 | 103
astrocytic glioma 1 | 2,597
gastric cancer 1 | 459
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
lung carcinoma 1 | 2,843
oligodendroglioma 1 | 2,850
posterior fossa group B ependymoma 1 | 416
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
tuberculosis 1 | 2,010

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Kinase 5 | 634
Non-IDG 4 | 12,091
Enzyme 1 | 4,145

Reactome Pathway

Receptor Mediated Mitophagy 10 | 10
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -1.21206 16.0 151
Serine/threonine-protein phosphatase PGAM5, mitochondrial PGAM5 Tbio Enzyme -1.40119 21.5 27
Casein kinase II subunit beta CSNK2B Tbio Kinase -2.72925 527.4 422
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Microtubule-associated proteins 1A/1B light chain 3A MAP1LC3A Tbio Non-IDG -2.18414 134.1 944
Casein kinase II subunit alpha' CSNK2A2 Tchem Kinase -2.34168 221.3 218
Serine/threonine-protein kinase ULK1 ULK1 Tchem Kinase -2.57033 346.8 647
Autophagy protein 5 ATG5 Tbio Non-IDG -2.88619 656.2 666
Microtubule-associated proteins 1A/1B light chain 3B MAP1LC3B Tbio Non-IDG -2.66114 391.8 772
Casein kinase II subunit alpha CSNK2A1 Tchem Kinase -2.35622 377.7 517