Development Level

Tbio 6 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46

Disease

Cancer 9 | 2,499
Rheumatoid arthritis 7 | 1,191
Hypersensitivity reaction type II disease 6 | 253
Arthritis, Rheumatoid 5 | 174
Multiple Sclerosis 5 | 540
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
tuberculosis 5 | 2,010
Acquired immunodeficiency syndrome 4 | 197
Adult T-Cell Lymphoma/Leukemia 4 | 30
Allergic hypersensitivity disease 4 | 126
Asthma 4 | 385
Carcinoma 4 | 11,493
Common variable immunodeficiency 4 | 101
Dermatitis 4 | 157
Diarrhea 4 | 253
Fever 4 | 138
Hepatitis B 4 | 108
Human immunodeficiency virus infectious disease 4 | 138
Kidney disease 4 | 430
Leishmaniasis 4 | 47
Leukemia-Lymphoma, Adult T-Cell 4 | 30
Major Depressive Disorder 4 | 301
Malaria 4 | 160
Neuropathy 4 | 261
Schizophrenia 4 | 1,160
Type 1 diabetes mellitus 4 | 109
Uveitis 4 | 103
osteosarcoma 4 | 7,950
ulcerative colitis 4 | 1,819
Allergic rhinitis 3 | 94
Alopecia areata 3 | 41
Anemia 3 | 365
Autoimmune hemolytic anemia 3 | 31
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Dermatitis, Allergic Contact 3 | 67
Diabetes Mellitus, Insulin-Dependent 3 | 48
Diabetes Mellitus, Type 1 3 | 43
Diphtheria 3 | 40
Eczema 3 | 45
Glomerulonephritis 3 | 46
HIV Infections 3 | 102
Hypereosinophilic syndrome 3 | 71
Inflammatory bowel disease 3 | 151
Kidney cancer 3 | 2,613
Liver disease 3 | 237
Lung disease 3 | 142
Lymphadenopathy 3 | 62
Lymphoproliferative syndrome 3 | 58
Melanoma 3 | 711
Splenomegaly 3 | 190
Thrombocytopenia 3 | 197
Unipolar Depression 3 | 250
Vasculitis 3 | 80
glioblastoma 3 | 5,792
Alopecia 2 | 115
Arthralgia 2 | 90
Atherosclerosis 2 | 291
Autistic Disorder 2 | 364
Autoimmune Diseases 2 | 67
Breast Neoplasms 2 | 445
Candidiasis 2 | 55
Celiac disease 2 | 116
Colitis 2 | 54
Collagen disease 2 | 27
Crohn Disease 2 | 45
Decreased platelet count 2 | 111
Encephalitis 2 | 64
Epistaxis 2 | 43
Exanthem 2 | 37
Fatigue 2 | 182
Graft vs Host Disease 2 | 6
Graft-vs-Host Disease 2 | 5
Heart disease 2 | 306
Hepatitis C 2 | 94
Hepatitis, Autoimmune 2 | 17
Hepatomegaly 2 | 285
Hypotension 2 | 82
Hypothyroidism 2 | 122
Immunologic Deficiency Syndromes 2 | 113
Influenza 2 | 142
Juvenile rheumatoid arthritis 2 | 111
Leukopenia 2 | 72
Lung Neoplasms 2 | 232
Lymphatic system disease 2 | 15
Mammary Neoplasms 2 | 425
Mesothelioma, Malignant 2 | 105
Neoplasms, Experimental 2 | 40
Primary cutaneous T-cell lymphoma 2 | 29
Proteinuria 2 | 144
Recurrent respiratory infections 2 | 141
Severe combined immunodeficiency 2 | 51
Systemic lupus erythematosus 2 | 194
Tetanus 2 | 68
Toxoplasmosis 2 | 17
sarcoidosis 2 | 370
tuberculosis and treatment for 3 months 2 | 179

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Cardiovascular System 8 | 15,192
Endocrine System 8 | 18,159
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678

Target Family

Non-IDG 6 | 12,091
Transcription Factor 3 | 1,400

Reactome Pathway

RUNX1 and FOXP3 control the de... 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Cytotoxic T-lymphocyte protein 4 CTLA4 Tclin Non-IDG -3.58565 3949.1 887
Tumor necrosis factor receptor superfamily member 18 TNFRSF18 Tbio Non-IDG -2.34111 233.7 604
Interleukin-2 receptor subunit alpha IL2RA Tclin Non-IDG -3.02107 927.8 1917
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
Forkhead box protein P3 FOXP3 Tbio Transcription Factor -3.80046 6233.8 1358
Runt-related transcription factor 1 RUNX1 Tbio Transcription Factor -3.25790 1899.3 798