Development Level

Tbio 61 | 11,651
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 44 | 11,493
ovarian cancer 42 | 8,520
lung cancer 27 | 4,740
osteosarcoma 27 | 7,950
group 3 medulloblastoma 24 | 4,104
medulloblastoma, large-cell 23 | 6,241
psoriasis 19 | 6,694
glioblastoma 17 | 5,792
Multiple myeloma 14 | 1,332
ependymoma 14 | 4,679
malignant mesothelioma 14 | 3,232
Breast cancer 13 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
atypical teratoid / rhabdoid tumor 11 | 5,112
Kidney cancer 10 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
non-small cell lung cancer 10 | 2,890
primitive neuroectodermal tumor 10 | 3,035
oligodendroglioma 9 | 2,850
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Pick disease 7 | 1,894
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
lung adenocarcinoma 7 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis and treatment for 6 months 7 | 409
Gaucher disease type 1 6 | 180
adult high grade glioma 6 | 3,801
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
subependymal giant cell astrocytoma 6 | 2,287
Intellectual disability 5 | 1,016
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
progressive supranuclear palsy 5 | 676
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
HIV Infections 4 | 102
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
atypical teratoid/rhabdoid tumor 4 | 357
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Bilateral fifth finger clinodactyly 3 | 110
Byzanthine arch palate 3 | 194
Curvature of little finger 3 | 110
Disease Progression 3 | 136
Epilepsy 3 | 792
Hematologic cancer 3 | 12
Immune system cancer 3 | 140
Microcephaly 3 | 166
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
pancreatic carcinoma 3 | 562
spina bifida 3 | 1,074
Adenocarcinoma of lung 2 | 142
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Feeding difficulties 2 | 127
Global developmental delay 2 | 608
Hypoplastic mandible condyle 2 | 275
Infertility 2 | 188
Low intelligence 2 | 645
Low set ears 2 | 181
Male infertility 2 | 206
Mandibular hypoplasia 2 | 275
Mastocytosis 2 | 27
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Micrognathism 2 | 275
Polycystic ovary syndrome 2 | 360
Polycythemia vera 2 | 27
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Short stature 2 | 531
Small head 2 | 374
Uranostaphyloschisis 2 | 167
Ventricular Septal Defects 2 | 119
gastric cancer 2 | 459
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
posterior fossa group B ependymoma 2 | 416
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 66 | 18,159
Blood and immune system 65 | 16,909
Cardiovascular System 65 | 15,192
Digestive Tract 65 | 17,369
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Male tissues 65 | 17,142
Nervous System 65 | 16,725
Respiratory system 65 | 16,393
Skin and soft tissues 65 | 17,230
Urinary Tract 65 | 16,678

Target Family

Non-IDG 59 | 12,091
Enzyme 6 | 4,145
Transcription Factor 1 | 1,400

Reactome Pathway

RNA Polymerase II Transcriptio... 66 | 66
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UAP56-interacting factor FYTTD1 Tbio Non-IDG -0.91558 8.46 108
Nuclear cap-binding protein subunit 2 NCBP2 Tbio Non-IDG -1.45099 24.2 110
Chromatin target of PRMT1 protein CHTOP Tbio Non-IDG -1.08937 13.2 96
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172
Polymerase delta-interacting protein 3 POLDIP3 Tbio Enzyme -1.11422 11.5 174
Poly(A) polymerase alpha PAPOLA Tbio Enzyme -0.76388 5.75 90
Splicing factor U2AF 65 kDa subunit U2AF2 Tbio Non-IDG -2.14043 127.8 183
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Cleavage and polyadenylation specificity factor subunit 5 NUDT21 Tbio Non-IDG -1.56364 34.0 119
Cleavage stimulation factor subunit 2 tau variant CSTF2T Tbio Non-IDG -0.87334 8.94 128