Development Level

Tbio 8 | 10,625
Tchem 2 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

absent pinna reflex 1 | 21
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 9 | 8,491
osteosarcoma 8 | 7,933
astrocytoma 5 | 1,493
glioblastoma 5 | 5,572
atypical teratoid / rhabdoid tumor 4 | 4,369
lung cancer 4 | 4,473
psoriasis 4 | 6,685
Carcinoma 3 | 2,147
Multiple myeloma 3 | 1,327
Neurodegenerative disease 3 | 383
Pick disease 3 | 1,893
Rheumatoid Arthritis 3 | 1,170
Waldenstrons macroglobulinemia 3 | 764
diabetes mellitus 3 | 1,663
lung carcinoma 3 | 2,844
medulloblastoma, large-cell 3 | 6,234
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
Cancer 2 | 2,346
Clostridium difficile colitis 2 | 12
Neuropathy 2 | 210
Paraplegia 2 | 71
SPOAN syndrome 2 | 2
dermatomyositis 2 | 966
group 3 medulloblastoma 2 | 2,254
group 4 medulloblastoma 2 | 1,875
hereditary spastic paraplegia 2 | 313
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
Aarskog-Scott syndrome 1 | 11
Adenocarcinoma 1 | 115
Adrenal Gland Neoplasms 1 | 11
Angioimmunoblastic Lymphadenopathy 1 | 4
Animal Mammary Neoplasms 1 | 135
Asthma 1 | 349
Atherosclerosis 1 | 275
Bladder Neoplasm 1 | 109
Cardiomyopathy, Dilated 1 | 47
Cerebrovascular disease 1 | 231
Crohn's disease 1 | 304
Down syndrome 1 | 548
Endometriosis 1 | 535
Fanconi syndrome 1 | 14
HIV Infections 1 | 99
Heart disease 1 | 279
Heart failure 1 | 80
Hypertension 1 | 293
IGA Glomerulonephritis 1 | 454
Impotence 1 | 45
Intellectual disability 1 | 573
Kidney disease 1 | 397
Liver carcinoma 1 | 217
Liver diseases 1 | 66
Lung disease 1 | 136
Lymphoma, T-Cell, Cutaneous 1 | 21
Malignant neoplasm of lung 1 | 16
Mammary Neoplasms, Experimental 1 | 149
Melanoma 1 | 261
Necrosis 1 | 51
Neoplasm Invasiveness 1 | 127
Neoplasm Metastasis 1 | 138
Neoplastic Cell Transformation 1 | 81
Neurofibromatosis 1 | 37
Oral hairy leukoplakia 1 | 6
Paratyphoid fever 1 | 10
Peripheral T-cell lymphoma 1 | 24
Proteinuria 1 | 63
Schizophrenia 1 | 503
Skin cancer 1 | 37
Stomach Neoplasms 1 | 282
T-Cell Lymphoma 1 | 11
Wiskott-Aldrich syndrome 1 | 27
acute myeloid leukemia 1 | 785
acute quadriplegic myopathy 1 | 1,157
adult high grade glioma 1 | 2,148
astrocytic glioma 1 | 2,241
atypical teratoid/rhabdoid tumor 1 | 1,095
cutaneous lupus erythematosus 1 | 1,056
ependymoma 1 | 2,514
facioscapulohumeral dystrophy 1 | 286
gastric cancer 1 | 436
hepatocellular carcinoma 1 | 550
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
non-small cell lung cancer 1 | 2,798
non-small cell lung carcinoma 1 | 413
pancreatic cancer 1 | 2,300
pancreatic carcinoma 1 | 567
posterior fossa group A ependymoma 1 | 1,511
primary pancreatic ductal adenocarcinoma 1 | 1,271
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 11 | 17,994
Cardiovascular System 11 | 17,957
Digestive Tract 11 | 18,472
Endocrine System 11 | 18,511
Female tissues 11 | 18,646
Liver and Pancreas 11 | 18,135
Male tissues 11 | 17,968
Nervous System 11 | 18,560
Respiratory system 11 | 17,483
Skin and soft tissues 11 | 18,114
Urinary Tract 11 | 18,443

Target Family

Non-IDG 7 | 11,969
Enzyme 4 | 4,146

Reactome Pathway

RHO GTPases activate KTN1 11 | 11
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.87449 73.5 395
Kinesin light chain 1 KLC1 Tbio Non-IDG -2.13747 25.8 144
Kinesin-1 heavy chain KIF5B Tchem Non-IDG -2.30310 188.2 283
Rho-related GTP-binding protein RhoG RHOG Tbio Enzyme -2.03228 104.0 127
Transforming protein RhoA RHOA Tbio Enzyme -3.51065 3096.5 467
Kinesin light chain 2 KLC2 Tbio Non-IDG -0.70148 4.64 136
Kinesin light chain 3 KLC3 Tbio Non-IDG -0.99841 10.1 83
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.35070 2084.6 341
Kinesin heavy chain isoform 5A KIF5A Tbio Non-IDG -1.65000 51.6 163
Kinectin KTN1 Tbio Non-IDG -1.90416 79.0 87