Development Level

Tbio 27 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased body weight 2 | 161
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
embryonic lethality prior to t... 2 | 278
increased mean corpuscular vol... 2 | 92
small testis 2 | 58
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
absent urinary bladder 1 | 1
anophthalmia 1 | 33
decreased circulating alanine ... 1 | 47
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
fusion of vertebral arches 1 | 7
increased CD4-positive, alpha ... 1 | 4
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
short tibia 1 | 97
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

ovarian cancer 25 | 8,520
Carcinoma 24 | 11,493
osteosarcoma 22 | 7,950
glioblastoma 18 | 5,792
medulloblastoma, large-cell 16 | 6,241
psoriasis 14 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
Breast cancer 11 | 3,578
Cancer 11 | 2,499
Wiskott-Aldrich syndrome 11 | 30
ependymoma 11 | 4,679
lung cancer 11 | 4,740
Astrocytoma, Pilocytic 10 | 3,081
juvenile dermatomyositis 10 | 1,187
subependymal giant cell astrocytoma 10 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primary Sjogren syndrome 9 | 735
Waldenstrons macroglobulinemia 8 | 765
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
primitive neuroectodermal tumor 8 | 3,035
Kidney cancer 7 | 2,613
Multiple myeloma 7 | 1,332
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Intellectual disability 6 | 1,016
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
cutaneous lupus erythematosus 6 | 1,057
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
pediatric high grade glioma 6 | 1,064
primary pancreatic ductal adenocarcinoma 6 | 1,109
Duchenne muscular dystrophy 5 | 601
diabetes mellitus 5 | 1,728
group 3 medulloblastoma 5 | 4,104
Bipolar Disorder 4 | 666
Fatigue 4 | 182
Fever 4 | 138
Immunologic Deficiency Syndromes 4 | 113
Mammary Neoplasms, Experimental 4 | 154
Neoplasm Invasiveness 4 | 161
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Animal Mammary Neoplasms 3 | 136
Arthritis 3 | 290
Attention deficit hyperactivity disorder 3 | 278
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Squamous Cell 3 | 110
Cell Transformation, Neoplastic 3 | 97
Chronic diarrhea 3 | 29
Chronic otitis media 3 | 52
Decreased platelet count 3 | 111
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Mammary Neoplasms, Animal 3 | 136
Neoplasm Metastasis 3 | 168
Neoplastic Cell Transformation 3 | 89
Nicotine dependence 3 | 54
Obesity 3 | 678
Paranasal Sinus Diseases 3 | 34
Parkinson's disease 3 | 392
Pointed chin 3 | 33
Short stature 3 | 531
Sinusitis 3 | 65
Squamous cell carcinoma 3 | 129
Thin upper lip vermilion 3 | 67
Thrombocytopenia 3 | 197
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ear infection chronic 3 | 52
gastric cancer 3 | 459
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
Amyotrophic lateral sclerosis 2 | 451
Autistic Disorder 2 | 364
Gliosis 2 | 56
Melanoma 2 | 711
Skin cancer 2 | 469
hereditary spastic paraplegia 2 | 318
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678

Target Family

Non-IDG 28 | 12,091
Kinase 5 | 634
Enzyme 2 | 4,145

Reactome Pathway

RHO GTPases Activate WASPs and... 35 | 35
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Actin-related protein 2 ACTR2 Tbio Non-IDG -1.88412 78.5 211
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.90666 762.6 254
Actin-related protein 2/3 complex subunit 2 ARPC2 Tbio Non-IDG -1.31089 16.9 270
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Actin-related protein 2/3 complex subunit 4 ARPC4 Tbio Non-IDG -1.00650 0.00000 120
Wiskott-Aldrich syndrome protein family member 1 WASF1 Tbio Non-IDG -3.07521 1145.9 216
Cytoplasmic FMR1-interacting protein 2 CYFIP2 Tbio Non-IDG -1.50813 23.0 99
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127