Development Level

Tbio 25 | 11,445
Tchem 10 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

decreased circulating creatini... 2 | 39
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
short tibia 1 | 97

Disease

Carcinoma 33 | 11,493
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 21 | 6,241
glioblastoma 20 | 5,792
ovarian cancer 20 | 8,520
Cancer 19 | 2,499
atypical teratoid / rhabdoid tumor 19 | 5,112
psoriasis 18 | 6,694
invasive ductal carcinoma 14 | 2,951
lung cancer 14 | 4,740
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Breast cancer 10 | 3,578
adult high grade glioma 10 | 3,801
lung adenocarcinoma 10 | 2,716
primitive neuroectodermal tumor 10 | 3,035
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Hirschsprung's disease 8 | 46
astrocytic glioma 8 | 2,597
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pancreatic cancer 8 | 2,398
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Bipolar Disorder 6 | 666
Parkinson's disease 6 | 392
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
Downward slant of palpebral fissure 5 | 158
Orbital separation excessive 5 | 244
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
spina bifida 5 | 1,074
Abdominal Pain 4 | 98
Acquired scoliosis 4 | 281
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Congenital Epicanthus 4 | 177
Constipation 4 | 181
Curvature of spine 4 | 282
Dyschezia 4 | 135
High forehead 4 | 102
Hypoplastic mandible condyle 4 | 275
Lung Neoplasms 4 | 232
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Multiple endocrine neoplasia type 2A 4 | 20
Multiple endocrine neoplasia type 2B 4 | 17
Muscle hypotonia 4 | 571
Nausea and vomiting 4 | 97
Noonan syndrome 4 | 34
Pectus excavatum 4 | 100
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Renal Cell Carcinoma 4 | 214
Tall forehead 4 | 102
Ventricular Septal Defects 4 | 119
Weight decreased 4 | 103
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
medulloblastoma 4 | 720
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Byzanthine arch palate 3 | 194
Cardiovascular Diseases 3 | 59
Concave bridge of nose 3 | 195
Delayed bone age 3 | 136
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Pediatric failure to thrive 3 | 365
Polycystic ovary syndrome 3 | 360
Posteriorly rotated ear 3 | 61
Seizures 3 | 596
Status Epilepticus 3 | 98
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
hepatocellular carcinoma 3 | 547
tuberculosis 3 | 2,010

Tissue

Endocrine System 39 | 18,159
Male tissues 38 | 17,142
Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Digestive Tract 37 | 17,369
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678

Target Family

Non-IDG 24 | 12,091
Kinase 11 | 634
Enzyme 5 | 4,145

Reactome Pathway

RET signaling 40 | 40
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Docking protein 6 DOK6 Tbio Non-IDG -0.45629 3.37 117
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
SHC-transforming protein 3 SHC3 Tbio Non-IDG -1.97665 99.4 137
Persephin PSPN Tbio Non-IDG -1.41761 21.8 153
Rap1 GTPase-activating protein 1 RAP1GAP Tbio Enzyme -1.86555 64.9 168
Docking protein 5 DOK5 Tbio Non-IDG -1.04456 11.4 284
Growth factor receptor-bound protein 10 GRB10 Tbio Non-IDG -1.98746 111.0 315
Docking protein 1 DOK1 Tbio Non-IDG -1.65046 43.4 676