Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal retina morphology 1 | 71
cataract 1 | 92
increased anti-nuclear antigen... 1 | 19
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
Congenital adrenal hyperplasia 4 | 73
Congenital adrenal insufficiency 4 | 7
atypical teratoid / rhabdoid tumor 4 | 5,112
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Anovulation 2 | 21
Anxiety disorder 2 | 23
Brain disease 2 | 96
Cerebrovascular disease 2 | 238
Cholesterol monooxygenase (side-chain cleaving) deficiency 2 | 2
Endometrial Neoplasms 2 | 55
Hyperandrogenism 2 | 34
Hypogonadism 2 | 173
Infertility 2 | 188
Kidney cancer 2 | 2,613
Lipoid congenital adrenal hyperplasia 2 | 2
Multiple Sclerosis 2 | 540
Polycystic ovary syndrome 2 | 360
Pontocerebellar hypoplasia 2 | 36
Proliferative diabetic retinopathy 2 | 4
Renal salt wasting 2 | 18
Toxic encephalopathy 2 | 141
adrenocortical carcinoma 2 | 1,428
cocaine use 2 | 11
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of cholesterol metabolism 1 | 3
Absence of secondary sex characteristics 1 | 22
Addison's disease 1 | 31
Adenoma 1 | 167
Adrenal cortical adenoma 1 | 19
Adrenocorticotropic hormone excess 1 | 5
Adrenogenital Syndrome 1 | 6
Autoimmune polyendocrine syndrome 1 | 6
Cerebrotendinous xanthomatosis 1 | 13
Cushing's syndrome 1 | 48
Decreased fertility 1 | 33
Dehydration 1 | 40
Delayed Puberty 1 | 97
Delayed bone age 1 | 136
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Elevated plasma renin 1 | 9
End Stage Liver Disease 1 | 4
Failure to gain weight 1 | 365
Female external genitalia in males 1 | 13
GLUCOCORTICOID DEFICIENCY 1 1 | 5
Gynecomastia 1 | 64
Hepatic encephalopathy 1 | 27
Hyperaldosteronism 1 | 35
Hyperkalemia 1 | 17
Hyperpigmentation 1 | 37
Hyponatremia 1 | 25
Hypospadias 1 | 53
Hypotension 1 | 82
Increased circulating ACTH level 1 | 8
Liver Cirrhosis, Experimental 1 | 769
Low maternal serum estriol 1 | 2
Low to undetectable plasma cortisol 1 | 12
Male Pseudohermaphroditism 1 | 19
Mitochondrial myopathy 1 | 26
Myoglobinuria 1 | 15
Neonatal hypoglycemia 1 | 17
Osteoporosis 1 | 363
Ovarian dysfunction 1 | 18
Pediatric failure to thrive 1 | 365
Penile hypospadias 1 | 106
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Premature ovarian failure 1 | 65
Retinitis pigmentosa 23 1 | 27
Secondary malignant neoplasm of female breast 1 | 3
Seizures 1 | 596
Sex reversal 1 | 10
Small testicle 1 | 75
Testicular Leydig cell tumor 1 | 2
Urogenital sinus anomaly 1 | 15
Vomiting 1 | 116
X-linked adrenal hypoplasia congenita 1 | 11
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
drug-induced hepatitis 1 | 44
locked-in syndrome 1 | 14
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Liver and Pancreas 10 | 16,750
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 10 | 12,091
Enzyme 2 | 4,145

Reactome Pathway

Pregnenolone biosynthesis 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
Ferredoxin-2, mitochondrial FDX2 Tdark Non-IDG -0.85150 6.83 4
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
StAR-related lipid transfer protein 6 STARD6 Tbio Non-IDG -1.03409 11.2 62
Peripheral-type benzodiazepine receptor-associated protein 1 TSPOAP1 Tbio Non-IDG -0.53932 4.30 18
Adrenodoxin, mitochondrial FDX1 Tbio Non-IDG -2.81884 673.3 46
StAR-related lipid transfer protein 4 STARD4 Tbio Non-IDG -1.14586 14.8 83
STARD3 N-terminal-like protein STARD3NL Tbio Non-IDG -0.59325 3.92 13
StAR-related lipid transfer protein 3 STARD3 Tbio Non-IDG -1.61721 39.4 37
Translocator protein TSPO Tchem Non-IDG -3.08695 2284.2 212