Development Level

Tbio 15 | 10,625
Tclin 7 | 602
Tchem 4 | 1,890
Tdark 1 | 7,003

IMPC Term

impaired righting response 1 | 19
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 18 | 8,484
lung cancer 13 | 4,466
Multiple myeloma 11 | 1,327
non-small cell lung cancer 11 | 2,798
Breast cancer 9 | 3,094
psoriasis 9 | 6,685
colon cancer 8 | 1,475
dermatomyositis 8 | 933
glioblastoma 8 | 5,572
Acute lymphoid leukemia 7 | 25
Anaplastic large T-cell systemic malignant lymphoma 7 | 10
Burkitt's lymphoma 7 | 15
Carcinoma of breast 7 | 11
Carcinoma of female breast 7 | 20
Diffuse non-Hodgkin's lymphoma, large cell 7 | 12
Follicular non-Hodgkin's lymphoma 7 | 17
Gestational trophoblastic neoplasia 7 | 14
HER2-positive carcinoma of breast 7 | 10
Hodgkin's disease 7 | 18
Hypertensive disorder 7 | 58
Kaposi's sarcoma 7 | 20
Langerhans cell histiocytosis, disseminated 7 | 10
Liposarcoma 7 | 20
Malignant tumor of head and/or neck 7 | 15
Malignant tumor of ovary 7 | 25
Malignant tumor of prostate 7 | 11
Malignant tumor of stomach 7 | 12
Malignant tumor of testis 7 | 11
Metastatic Breast Carcinoma 7 | 21
Metastatic Prostate Carcinoma 7 | 18
Mycosis fungoides 7 | 28
Nephroblastoma 7 | 45
Neuroblastoma 7 | 78
Non-Hodgkin's lymphoma 7 | 22
Ocular hypertension 7 | 27
Open-angle glaucoma 7 | 26
Rhabdomyosarcoma 7 | 29
Secondary malignant neoplasm of pancreas 7 | 10
Transitional cell carcinoma 7 | 18
breast carcinoma 7 | 1,614
medulloblastoma, large-cell 7 | 6,234
osteosarcoma 7 | 7,933
pancreatic cancer 7 | 2,300
Waldenstrons macroglobulinemia 6 | 765
ependymoma 6 | 2,514
acute quadriplegic myopathy 5 | 1,157
atypical teratoid / rhabdoid tumor 5 | 4,369
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung adenocarcinoma 5 | 2,713
nasopharyngeal carcinoma 5 | 1,056
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
Condyloma acuminatum 4 | 7
Duchenne muscular dystrophy 4 | 602
Lissencephaly 4 | 61
astrocytic glioma 4 | 2,241
invasive ductal carcinoma 4 | 2,950
malignant mesothelioma 4 | 3,162
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
Becker muscular dystrophy 3 | 187
Cancer 3 | 2,346
Down syndrome 3 | 548
HIV Infections 3 | 100
Microcephaly 3 | 149
Pick disease 3 | 1,893
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
diabetes mellitus 3 | 1,663
juvenile dermatomyositis 3 | 1,189
oligodendroglioma 3 | 2,849
sonic hedgehog group medulloblastoma 3 | 1,482
Amyotrophic Lateral Sclerosis 2 | 431
Animal Mammary Neoplasms 2 | 136
Dystonia 2 | 77
Intellectual disability 2 | 573
Mammary Neoplasms 2 | 410
Mammary Neoplasms, Experimental 2 | 150
Myocardial Ischemia 2 | 169
Neuropathy 2 | 210
Peripheral Neuropathy 2 | 303
Stomach Neoplasms 2 | 282
adult high grade glioma 2 | 2,148
gastric cancer 2 | 430
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
interstitial cystitis 2 | 2,299
limb girdle muscular dystrophy 2B 2 | 74
lung carcinoma 2 | 2,844
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 27 | 17,995
Cardiovascular System 27 | 17,958
Digestive Tract 27 | 18,473
Endocrine System 27 | 18,512
Female tissues 27 | 18,647
Liver and Pancreas 27 | 18,136
Male tissues 27 | 17,969
Nervous System 27 | 18,561
Respiratory system 27 | 17,484
Skin and soft tissues 27 | 18,115
Urinary Tract 27 | 18,444

Target Family

Non-IDG 27 | 11,971

Reactome Pathway

Prefoldin mediated transfer of... 27 | 27
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
T-complex protein 1 subunit delta CCT4 Tbio Non-IDG -1.76354 56.6 151
T-complex protein 1 subunit theta CCT8 Tbio Non-IDG -1.45966 29.4 180
T-complex protein 1 subunit epsilon CCT5 Tbio Non-IDG -1.39059 24.5 183
Tubulin alpha-1A chain TUBA1A Tchem Non-IDG -1.55267 35.2 218
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.83965 6.79 66
T-complex protein 1 subunit gamma CCT3 Tbio Non-IDG -2.17641 143.4 144
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.24508 169.4 383
T-complex protein 1 subunit eta CCT7 Tbio Non-IDG -1.42149 25.9 158
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.94467 854.1 71