Development Level

Tbio 79 | 11,445
Tchem 19 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
abnormal seminal vesicle morph... 5 | 114
preweaning lethality, complete... 4 | 979
short tibia 4 | 97
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
enlarged heart 3 | 210
increased circulating alkaline... 3 | 122
increased circulating triglyce... 3 | 42
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal tooth morphology 2 | 24
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal incisor morphology 1 | 4
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal radius morphology 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
absent testes 1 | 6
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged testis 1 | 6
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
pallor 1 | 34
premature death 1 | 5
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36
syndactyly 1 | 23

Disease

Carcinoma 75 | 11,493
ovarian cancer 69 | 8,520
psoriasis 58 | 6,694
glioblastoma 49 | 5,792
osteosarcoma 46 | 7,950
lung cancer 45 | 4,740
medulloblastoma, large-cell 45 | 6,241
atypical teratoid / rhabdoid tumor 41 | 5,112
diabetes mellitus 39 | 1,728
Cancer 38 | 2,499
ependymoma 38 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
pancreatic cancer 38 | 2,398
lung carcinoma 37 | 2,843
Breast cancer 36 | 3,578
malignant mesothelioma 36 | 3,232
invasive ductal carcinoma 34 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
non-small cell lung cancer 31 | 2,890
Astrocytoma, Pilocytic 30 | 3,081
lung adenocarcinoma 29 | 2,716
cystic fibrosis 28 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
ulcerative colitis 26 | 1,819
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
juvenile dermatomyositis 24 | 1,187
Autosomal recessive predisposition 23 | 1,442
pituitary cancer 23 | 1,972
primary pancreatic ductal adenocarcinoma 23 | 1,109
Kidney cancer 22 | 2,613
adrenocortical carcinoma 22 | 1,428
tuberculosis 22 | 2,010
ductal carcinoma in situ 21 | 1,745
Duchenne muscular dystrophy 20 | 601
breast carcinoma 20 | 1,638
oligodendroglioma 20 | 2,850
Atherosclerosis 19 | 291
Kidney disease 19 | 430
gastric carcinoma 19 | 807
interstitial cystitis 19 | 2,312
primitive neuroectodermal tumor 19 | 3,035
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
group 3 medulloblastoma 18 | 4,104
pediatric high grade glioma 18 | 1,064
subependymal giant cell astrocytoma 18 | 2,287
Liver disease 17 | 237
Rheumatoid arthritis 17 | 1,191
Coronary artery disease 16 | 268
Hypertension 16 | 396
esophageal adenocarcinoma 16 | 737
group 4 medulloblastoma 16 | 1,855
Obesity 15 | 678
active Crohn's disease 15 | 922
acute quadriplegic myopathy 15 | 1,158
Liver Cirrhosis, Experimental 14 | 769
colon cancer 14 | 1,478
nasopharyngeal carcinoma 14 | 1,058
Heart disease 13 | 306
Osteoporosis 13 | 363
astrocytic glioma 13 | 2,597
Cerebrovascular disease 12 | 238
Liver Cirrhosis 12 | 181
Schizophrenia 12 | 1,160
astrocytoma 12 | 1,146
dermatomyositis 12 | 966
interstitial lung disease 12 | 298
Atopic dermatitis 11 | 952
Becker muscular dystrophy 11 | 191
Breast Neoplasms 11 | 445
Down syndrome 11 | 499
Endometriosis 11 | 540
Hypertensive disease 11 | 292
Melanoma 11 | 711
Pick disease 11 | 1,894
Vascular disease 11 | 319
limb girdle muscular dystrophy 2A 11 | 213
Alzheimer's disease 10 | 658
Bipolar Disorder 10 | 666
Cardiovascular system disease 10 | 246
Chemical and Drug Induced Liver Injury 10 | 195
Mammary Neoplasms 10 | 425
Prostatic Neoplasms 10 | 495
Stomach Neoplasms 10 | 300
active ulcerative colitis 10 | 764
aldosterone-producing adenoma 10 | 665
fibroadenoma 9 | 559
posterior fossa group A ependymoma 9 | 468
sonic hedgehog group medulloblastoma 9 | 467
Arthritis 8 | 290
Carcinoma, Hepatocellular 8 | 228
Hepatomegaly 8 | 285
Lipid metabolism disorder 8 | 114
Liver carcinoma 8 | 240
Polycystic ovary syndrome 8 | 360
Proteinuria 8 | 144
Thrombophilia 8 | 38
head and neck cancer and chronic obstructive pulmonary disease 8 | 239
medulloblastoma 8 | 720
non primary Sjogren syndrome sicca 8 | 891

Tissue

Endocrine System 104 | 18,159
Female tissues 101 | 17,400
Liver and Pancreas 100 | 16,750
Digestive Tract 99 | 17,369
Male tissues 99 | 17,142
Blood and immune system 98 | 16,909
Skin and soft tissues 98 | 17,230
Urinary Tract 97 | 16,678
Nervous System 95 | 16,725
Respiratory system 94 | 16,393
Cardiovascular System 88 | 15,192

Target Family

Non-IDG 89 | 12,091
Enzyme 16 | 4,145

Reactome Pathway

Post-translational protein pho... 105 | 105
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anoctamin-8 ANO8 Tbio Non-IDG -0.24444 1.60 13
Matrix remodeling-associated protein 8 MXRA8 Tdark Non-IDG -0.36209 1.25 8
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Mesothelin MSLN Tbio Non-IDG -2.66061 452.1 542
Kinectin KTN1 Tbio Non-IDG -1.93411 83.4 89
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Secretogranin-2 SCG2 Tbio Non-IDG -2.37107 283.4 175