Development Level

Tbio 71 | 11,445
Tdark 15 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal seminal vesicle morph... 3 | 114
decreased circulating glucose ... 3 | 126
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal heart morphology 2 | 162
decreased eosinophil cell numb... 2 | 24
decreased total body fat amoun... 2 | 207
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal eye morphology 1 | 68
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
bleb 1 | 2
brachydactyly 1 | 19
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
female infertility 1 | 60
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 42 | 11,493
psoriasis 42 | 6,694
ovarian cancer 40 | 8,520
osteosarcoma 36 | 7,950
medulloblastoma, large-cell 27 | 6,241
glioblastoma 26 | 5,792
non-small cell lung cancer 26 | 2,890
lung adenocarcinoma 25 | 2,716
atypical teratoid / rhabdoid tumor 24 | 5,112
lung carcinoma 24 | 2,843
ependymoma 22 | 4,679
lung cancer 22 | 4,740
adult high grade glioma 20 | 3,801
cystic fibrosis 18 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
tuberculosis 18 | 2,010
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
oligodendroglioma 17 | 2,850
pancreatic cancer 17 | 2,398
Breast cancer 16 | 3,578
group 3 medulloblastoma 16 | 4,104
malignant mesothelioma 16 | 3,232
Astrocytoma, Pilocytic 15 | 3,081
astrocytic glioma 14 | 2,597
ductal carcinoma in situ 14 | 1,745
invasive ductal carcinoma 14 | 2,951
primitive neuroectodermal tumor 14 | 3,035
ulcerative colitis 12 | 1,819
pituitary cancer 11 | 1,972
Cancer 10 | 2,499
Epilepsy 10 | 792
Intellectual disability 10 | 1,016
Kidney cancer 10 | 2,613
breast carcinoma 10 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Autosomal recessive predisposition 9 | 1,442
cutaneous lupus erythematosus 9 | 1,057
Pick disease 8 | 1,894
Seizures 8 | 596
esophageal adenocarcinoma 8 | 737
nasopharyngeal carcinoma 8 | 1,058
primary pancreatic ductal adenocarcinoma 8 | 1,109
subependymal giant cell astrocytoma 8 | 2,287
active Crohn's disease 7 | 922
adrenocortical carcinoma 7 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atopic dermatitis 6 | 952
Schizophrenia 6 | 1,160
active ulcerative colitis 6 | 764
colon cancer 6 | 1,478
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
Autistic Disorder 5 | 364
Cerebral atrophy 5 | 178
Concave bridge of nose 5 | 195
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Iridogoniodysgenesis syndrome 5 | 9
Muscle hypotonia 5 | 571
Paroxysmal nocturnal hemoglobinuria 5 | 10
Rheumatoid arthritis 5 | 1,191
fibroadenoma 5 | 559
head and neck cancer 5 | 271
Acquired metabolic disease 4 | 336
Anemia 4 | 365
Bipolar Disorder 4 | 666
Congenital muscular dystrophy 4 | 29
Duchenne muscular dystrophy 4 | 601
Hyperphosphatasia with Mental Retardation 4 | 5
Hypoplastic mandible condyle 4 | 275
Mal de Meleda 4 | 7
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Multiple myeloma 4 | 1,332
astrocytoma 4 | 1,146
mucosa-associated lymphoid tissue lymphoma 4 | 484
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
Bilateral fifth finger clinodactyly 3 | 110
Byzanthine arch palate 3 | 194
Curvature of little finger 3 | 110
Down syndrome 3 | 499
Elevated creatine kinase 3 | 110
Kidney disease 3 | 430
Long philtrum 3 | 137
Major Depressive Disorder 3 | 301
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Unipolar Depression 3 | 250
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
urothelial carcinoma 3 | 318

Tissue

Digestive Tract 91 | 17,369
Endocrine System 90 | 18,159
Female tissues 88 | 17,400
Skin and soft tissues 88 | 17,230
Blood and immune system 86 | 16,909
Male tissues 86 | 17,142
Liver and Pancreas 85 | 16,750
Nervous System 82 | 16,725
Urinary Tract 82 | 16,678
Respiratory system 79 | 16,393
Cardiovascular System 70 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 32 | 4,145

Reactome Pathway

Post-translational modificatio... 93 | 93
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Testis-expressed protein 101 TEX101 Tbio Non-IDG -1.34939 22.8 30
Shadow of prion protein SPRN Tbio Non-IDG -2.49698 315.1 88
Beta-tectorin TECTB Tbio Non-IDG -1.23705 16.8 72
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
Lymphocyte antigen 6H LY6H Tdark Non-IDG -0.76039 4.88 44
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.18571 13.8 39
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Prion-like protein doppel PRND Tbio Non-IDG -2.49819 344.5 33
Limbic system-associated membrane protein LSAMP Tbio Non-IDG -1.72744 52.8 72
Mesothelin MSLN Tbio Non-IDG -2.66061 452.1 542