Development Level

Tbio 96 | 11,445
Tchem 16 | 1,598
Tdark 8 | 6,588
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 6 | 499
enlarged heart 4 | 210
abnormal seminal vesicle morph... 3 | 114
decreased circulating insulin ... 3 | 76
decreased vertical activity 3 | 208
edema 3 | 59
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
increased or absent threshold ... 2 | 101
male infertility 2 | 123
abnormal QT variability 1 | 10
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
corneal opacity 1 | 32
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hypoactivity 1 | 132
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
premature death 1 | 5
short tibia 1 | 97

Disease

Carcinoma 79 | 11,493
ovarian cancer 77 | 8,520
Cancer 64 | 2,499
glioblastoma 64 | 5,792
psoriasis 63 | 6,694
osteosarcoma 61 | 7,950
lung cancer 56 | 4,740
pancreatic cancer 53 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
Astrocytoma, Pilocytic 44 | 3,081
ependymoma 44 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
invasive ductal carcinoma 44 | 2,951
lung carcinoma 44 | 2,843
malignant mesothelioma 44 | 3,232
medulloblastoma, large-cell 44 | 6,241
Breast cancer 43 | 3,578
atypical teratoid / rhabdoid tumor 43 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,989
diabetes mellitus 39 | 1,728
lung adenocarcinoma 39 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
adult high grade glioma 32 | 3,801
non-small cell lung cancer 32 | 2,890
Liver Cirrhosis, Experimental 31 | 769
tuberculosis 31 | 2,010
cystic fibrosis 28 | 1,696
interstitial cystitis 28 | 2,312
Autosomal recessive predisposition 27 | 1,442
Kidney disease 27 | 430
Duchenne muscular dystrophy 26 | 601
breast carcinoma 26 | 1,638
oligodendroglioma 25 | 2,850
subependymal giant cell astrocytoma 25 | 2,287
ulcerative colitis 25 | 1,819
Atherosclerosis 24 | 291
Coronary artery disease 23 | 268
group 3 medulloblastoma 23 | 4,104
juvenile dermatomyositis 23 | 1,187
primary pancreatic ductal adenocarcinoma 23 | 1,109
astrocytic glioma 22 | 2,597
Kidney cancer 21 | 2,613
colon cancer 21 | 1,478
Thrombocytopenia 20 | 197
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
ductal carcinoma in situ 20 | 1,745
gastric carcinoma 20 | 807
pancreatic carcinoma 20 | 562
Cerebrovascular disease 19 | 238
Hypertension 19 | 396
Vascular disease 19 | 319
adrenocortical carcinoma 19 | 1,428
primitive neuroectodermal tumor 19 | 3,035
Heart disease 18 | 306
acute quadriplegic myopathy 18 | 1,158
Alzheimer's disease 17 | 658
Hypertensive disease 17 | 292
Liver disease 17 | 237
Pick disease 17 | 1,894
Schizophrenia 17 | 1,160
astrocytoma 17 | 1,146
esophageal adenocarcinoma 17 | 737
pediatric high grade glioma 17 | 1,064
pituitary cancer 17 | 1,972
Obesity 16 | 678
group 4 medulloblastoma 16 | 1,855
Rheumatoid arthritis 15 | 1,191
Thrombophilia 15 | 38
Arthritis 14 | 290
Liver Cirrhosis 14 | 181
Multiple myeloma 14 | 1,332
dermatomyositis 14 | 966
Chemical and Drug Induced Liver Injury 13 | 195
mucosa-associated lymphoid tissue lymphoma 13 | 484
Atopic dermatitis 12 | 952
Becker muscular dystrophy 12 | 191
Breast Neoplasms 12 | 445
Carcinoma, Hepatocellular 12 | 228
Liver carcinoma 12 | 240
Mammary Neoplasms 12 | 425
Neoplasm Invasiveness 12 | 161
Osteoporosis 12 | 363
Polycystic ovary syndrome 12 | 360
Prostatic Neoplasms 12 | 495
Pulmonary Fibrosis 12 | 106
gastric cancer 12 | 459
limb girdle muscular dystrophy 2A 12 | 213
Anemia 11 | 365
Asthma 11 | 385
Down syndrome 11 | 499
Pulmonary embolism 11 | 55
Depressive disorder 10 | 409
Endometriosis 10 | 540
Hypersensitivity reaction type II disease 10 | 253
Neoplasm Metastasis 10 | 168
active Crohn's disease 10 | 922
cutaneous lupus erythematosus 10 | 1,057
fibroadenoma 10 | 559
Bipolar Disorder 9 | 666
sonic hedgehog group medulloblastoma 9 | 467

Tissue

Endocrine System 123 | 18,159
Liver and Pancreas 123 | 16,750
Skin and soft tissues 123 | 17,230
Urinary Tract 123 | 16,678
Digestive Tract 122 | 17,369
Female tissues 122 | 17,400
Male tissues 121 | 17,142
Blood and immune system 120 | 16,909
Respiratory system 119 | 16,393
Nervous System 118 | 16,725
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 101 | 12,091
Enzyme 22 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

Reactome Pathway

Platelet degranulation 126 | 126
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Bromodomain and PHD finger-containing protein 3 BRPF3 Tchem Epigenetic -0.46982 2.70 64
Torsin-4A TOR4A Tdark Non-IDG 0.77 0.09 17
NADH-cytochrome b5 reductase 1 CYB5R1 Tbio Enzyme -0.95573 7.22 142
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101