Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

increased kidney weight 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
osteosarcoma 6 | 7,950
psoriasis 6 | 6,694
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
Cancer 4 | 2,499
Cardiomegaly 4 | 116
Cardiomyopathy 4 | 116
Holt-Oram syndrome 4 | 12
Hypertension 4 | 396
Rheumatoid arthritis 4 | 1,191
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
group 4 medulloblastoma 4 | 1,855
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 3 | 21
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Autosomal recessive predisposition 3 | 1,442
Brachydactyly 3 | 156
Breast cancer 3 | 3,578
Congenital heart disease 3 | 93
Down syndrome 3 | 499
Familial atrial fibrillation 3 | 23
Heart disease 3 | 306
Long narrow head 3 | 75
Myocardial Infarction 3 | 151
Narrow cranium shape 3 | 75
Narrow head shape 3 | 75
Narrow skull shape 3 | 75
Pick disease 3 | 1,894
Turridolichocephaly 3 | 75
Ventricular Septal Defects 3 | 119
astrocytic glioma 3 | 2,597
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Abnormal nasal morphology 2 | 16
Acromesomelic dysplasia 2 | 10
Amyotrophic lateral sclerosis 2 | 451
Atrial Septal Defects 2 | 85
Atrial heart septal defect 2 | 18
Atrioventricular block 2 | 35
Bilateral fifth finger clinodactyly 2 | 110
Broad forehead 2 | 59
Broad hallux 2 | 29
Cardiomyopathy, Dilated 2 | 83
Cognitive delay 2 | 608
Coronary artery disease 2 | 268
Curvature of little finger 2 | 110
Diaphragmatic Hernia 2 | 40
Ebstein anomaly 2 | 16
Exophthalmos 2 | 112
Fetal Growth Retardation 2 | 189
Gastrointestinal Stromal Tumors 2 | 48
Global developmental delay 2 | 608
Heart Septal Defects, Ventricular 2 | 6
Heart failure 2 | 162
Hernia, Diaphragmatic 2 | 40
Hypertensive disease 2 | 292
Hypoplastic Left Heart Syndrome 2 | 14
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Mental and motor retardation 2 | 608
Ostium secundum atrial septal defect 2 | 9
Pain 2 | 103
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Pulmonary valve stenosis 2 | 9
Right atrial isomerism 2 | 29
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
Tetralogy of Fallot 2 | 63
Thin lips 2 | 49
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38
Ureteral obstruction 2 | 33
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
fibroadenoma 2 | 559
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
ventricular septal defect 2 | 20

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Female tissues 11 | 17,400
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Male tissues 10 | 17,142
Respiratory system 10 | 16,393
Urinary Tract 10 | 16,678
Liver and Pancreas 9 | 16,750
Skin and soft tissues 9 | 17,230
Nervous System 8 | 16,725

Target Family

Kinase 4 | 634
Non-IDG 3 | 12,091
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

Reactome Pathway

Physiological factors 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-type natriuretic peptide NPPC Tbio Non-IDG -2.91034 740.1 175
Atrial natriuretic peptide receptor 1 NPR1 Tclin Kinase -2.61776 410.0 214
Transcription factor GATA-4 GATA4 Tbio Transcription Factor -2.90202 763.9 496
Homeodomain-interacting protein kinase 1 HIPK1 Tchem Kinase -0.65413 5.10 194
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385
Natriuretic peptides A NPPA Tchem Non-IDG -3.25145 1788.9 509
Homeodomain-interacting protein kinase 2 HIPK2 Tchem Kinase -2.07209 135.4 287
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.62847 372.0 331
WW domain-containing transcription regulator protein 1 WWTR1 Tbio Non-IDG -2.12172 146.8 193
Atrial natriuretic peptide receptor 2 NPR2 Tbio Kinase -2.11421 138.1 180