Development Level

Tbio 75 | 11,445
Tchem 16 | 1,598
Tdark 15 | 6,588
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal spleen morphology 2 | 55
decreased mean corpuscular vol... 2 | 79
increased startle reflex 2 | 112
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
cleft palate 1 | 8
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
protruding tongue 1 | 3
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 58 | 11,493
psoriasis 43 | 6,694
ovarian cancer 41 | 8,520
osteosarcoma 35 | 7,950
Cancer 32 | 2,499
glioblastoma 26 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
medulloblastoma, large-cell 22 | 6,241
malignant mesothelioma 20 | 3,232
Schizophrenia 19 | 1,160
lung cancer 18 | 4,740
lung carcinoma 18 | 2,843
Breast cancer 17 | 3,578
Prostatic Neoplasms 17 | 495
atypical teratoid / rhabdoid tumor 17 | 5,112
invasive ductal carcinoma 17 | 2,951
tuberculosis 16 | 2,010
ependymoma 15 | 4,679
lung adenocarcinoma 15 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
colon cancer 13 | 1,478
pancreatic cancer 13 | 2,398
Anemia 12 | 365
Autosomal recessive predisposition 12 | 1,442
Chemical and Drug Induced Liver Injury 12 | 195
astrocytic glioma 12 | 2,597
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Astrocytoma, Pilocytic 11 | 3,081
Bilirubin metabolic disorder 11 | 41
cystic fibrosis 11 | 1,696
interstitial cystitis 11 | 2,312
primitive neuroectodermal tumor 11 | 3,035
Multiple myeloma 10 | 1,332
adult high grade glioma 10 | 3,801
diabetes mellitus 10 | 1,728
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 4,104
Pick disease 9 | 1,894
Sickle Cell Anemia 9 | 53
oligodendroglioma 9 | 2,850
subependymal giant cell astrocytoma 9 | 2,287
Bipolar Disorder 8 | 666
Bladder Neoplasm 8 | 112
Hypertension 8 | 396
Urinary Bladder Neoplasms 8 | 114
group 4 medulloblastoma 8 | 1,855
Cholestasis 7 | 155
Liver Cirrhosis, Experimental 7 | 769
Lung Neoplasms 7 | 232
Pericholangitis 7 | 8
Waldenstrons macroglobulinemia 7 | 765
acute quadriplegic myopathy 7 | 1,158
hepatocellular carcinoma 7 | 547
pituitary cancer 7 | 1,972
Adverse reaction to drug 6 | 61
Attention deficit hyperactivity disorder 6 | 278
Chromosome Aberrations 6 | 16
Down syndrome 6 | 499
Drug-Related Side Effects and Adverse Reactions 6 | 62
Liver disease 6 | 237
Neurodegenerative Diseases 6 | 38
Neurodegenerative Disorders 6 | 79
adrenocortical carcinoma 6 | 1,428
nasopharyngeal carcinoma 6 | 1,058
primary Sjogren syndrome 6 | 735
spina bifida 6 | 1,074
Alcoholic Intoxication, Chronic 5 | 289
Barrett's esophagus 5 | 182
Cleft Palate 5 | 271
Contact Dermatitis 5 | 81
Dermatitis, Contact 5 | 71
Epilepsy 5 | 792
Myocardial Ischemia 5 | 169
Non-alcoholic Fatty Liver Disease 5 | 42
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
esophageal adenocarcinoma 5 | 737
gastric cancer 5 | 459
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
Amphetamine-Related Disorders 4 | 74
Asthma 4 | 385
Carcinoma, Hepatocellular 4 | 228
Coronary artery disease 4 | 268
Depressive disorder 4 | 409
Liver carcinoma 4 | 240
Liver diseases 4 | 87
Male infertility 4 | 206
Mental Depression 4 | 333
astrocytoma 4 | 1,146
medulloblastoma 4 | 720
nephrosclerosis 4 | 333
non diabetic and post-ischemic heart failure 4 | 200
tuberculosis and treatment for 3 months 4 | 179

Tissue

Digestive Tract 102 | 17,369
Liver and Pancreas 101 | 16,750
Skin and soft tissues 98 | 17,230
Urinary Tract 97 | 16,678
Endocrine System 96 | 18,159
Female tissues 95 | 17,400
Male tissues 94 | 17,142
Blood and immune system 92 | 16,909
Nervous System 87 | 16,725
Respiratory system 82 | 16,393
Cardiovascular System 75 | 15,192

Target Family

Enzyme 100 | 4,145
Transporter 4 | 473
Non-IDG 2 | 12,091
Ion Channel 1 | 344

Reactome Pathway

Phase II - Conjugation of comp... 107 | 107
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
Putative glutathione hydrolase 3 proenzyme GGT3P Tdark Enzyme -3.09193 1683.2 0
Methionine synthase MTR Tbio Enzyme -2.56900 300.2 87
Arsenite methyltransferase AS3MT Tbio Enzyme -2.10657 132.7 88
Sulfotransferase 1A3 SULT1A3 Tbio Enzyme -2.23459 201.6 133
Sulfotransferase 1A4 SULT1A3 Tbio Enzyme -2.23459 201.6 40
Glutathione S-transferase theta-2 GSTT2 Tbio Enzyme -1.25193 16.8 0
Sulfate transporter SLC26A2 Tbio Transporter -2.46180 284.1 76
Glycine N-acyltransferase GLYAT Tbio Enzyme -1.91086 76.4 110
Glutathione-specific gamma-glutamylcyclotransferase 1 CHAC1 Tbio Enzyme -1.29114 18.9 179