Development Level

Tbio 4 | 11,445
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased vertical activity 1 | 24

Disease

Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
medulloblastoma, large-cell 5 | 6,241
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
oligodendroglioma 4 | 2,850
Heart disease 3 | 306
Multiple Sclerosis 3 | 540
Pick disease 3 | 1,894
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
Astrocytoma, Pilocytic 2 | 3,081
Eaton-Lambert syndrome 2 | 40
Kidney cancer 2 | 2,613
Spinocerebellar ataxia type 19/22 2 | 2
astrocytic glioma 2 | 2,597
fibroadenoma 2 | 559
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Alzheimer's disease 1 | 658
Astigmatism 1 | 54
Ataxia, Appendicular 1 | 25
Ataxia, Truncal 1 | 21
Atrial Fibrillation 1 | 124
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
BRUGADA SYNDROME 9 1 | 1
Brugada Syndrome (disorder) 1 | 15
Brugada syndrome 1 | 29
Cerebellar Ataxia 1 | 304
Cerebellar degeneration 1 | 103
Cycloplegia 1 | 12
Decreased tendon reflex 1 | 122
Deglutition Disorders 1 | 132
Dysarthria 1 | 192
Endometrial cancer 1 | 311
Epilepsy 1 | 792
Gait Ataxia 1 | 51
Gaze-evoked horizontal nystagmus 1 | 1
Infratentorial atrophy 1 | 103
Intermittent microsaccadic pursuits 1 | 1
Leiomyosarcoma 1 | 24
Mental Depression 1 | 333
Myoclonus 1 | 74
Neurodegenerative disease 1 | 414
Palpitations 1 | 18
Parkinson's disease 1 | 392
Pneumonia 1 | 174
Progressive cerebellar ataxia 1 | 13
Slow progression 1 | 89
Spinocerebellar ataxia 19 1 | 1
Static Tremor 1 | 21
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dentatorubral-pallidoluysian atrophy 1 | 21
ductal carcinoma in situ 1 | 1,745
epithelial-myoepithelial carcinoma 1 | 6
interstitial cystitis 1 | 2,312
medulloblastoma 1 | 720
megacystis-microcolon-intestinal hypoperistalsis syndrome 1 | 10
non diabetic and post-ischemic heart failure 1 | 200
non primary Sjogren syndrome sicca 1 | 891
non-inflammatory breast cancer 1 | 66
primitive neuroectodermal tumor 1 | 3,035
progressive supranuclear palsy 1 | 676
psoriasis 1 | 6,694
sonic hedgehog group medulloblastoma 1 | 467
substance-related disorder 1 | 162
type II diabetes mellitus and post-ischemic heart failure 1 | 88
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Ion Channel 6 | 344

Reactome Pathway

Phase 1 - inactivation of fast... 6 | 6
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Calsenilin KCNIP3 Tbio Ion Channel -1.72310 56.0 369
Kv channel-interacting protein 1 KCNIP1 Tbio Ion Channel -1.52487 33.1 222
Potassium voltage-gated channel subfamily D member 2 KCND2 Tclin Ion Channel -2.39309 245.7 317
Kv channel-interacting protein 4 KCNIP4 Tbio Ion Channel -1.66162 49.4 147
Kv channel-interacting protein 2 KCNIP2 Tbio Ion Channel -1.86621 71.6 314