Development Level

Tbio 23 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

male infertility 2 | 123
abnormal snout morphology 1 | 23
decreased circulating sodium l... 1 | 22
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 14 | 11,493
ovarian cancer 11 | 8,520
Kidney cancer 9 | 2,613
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 8 | 7,950
lung cancer 7 | 4,740
Breast cancer 6 | 3,578
Infertility 6 | 188
Male infertility 6 | 206
glioblastoma 6 | 5,792
Cancer 5 | 2,499
Multiple myeloma 5 | 1,332
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Hereditary spherocytosis type 5 4 | 12
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
Chikungunya 3 | 16
diabetes mellitus 3 | 1,728
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
Azoospermia 2 | 110
Cockayne syndrome 2 | 60
Congenital myasthenic syndrome 5 2 | 11
Klinefelter's syndrome 2 | 56
Melanoma 2 | 711
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
tuberculosis 2 | 2,010
Acute cor pulmonale 1 | 5
Adenoid Cystic Carcinoma 1 | 99
Astrocytoma, Pilocytic 1 | 3,081
Attention deficit hyperactivity disorder 1 | 278
Autoimmune polyendocrine syndrome type 1 1 | 9
Barth syndrome 1 | 23
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Candidiasis 1 | 55
Carcinoma, Adenoid Cystic 1 | 99
Chediak-Higashi syndrome 1 | 26
Chromosome 17q12 deletion syndrome 1 | 16
Contact Dermatitis 1 | 81
Dermatitis, Contact 1 | 71
Eumycotic mycetoma 1 | 3
Fusariosis 1 | 6
Glioma 1 | 74
HIV Infections 1 | 102
Large intestine cancer 1 | 126
Major Depressive Disorder 1 | 301
Malaria 1 | 160
Mammary Neoplasms 1 | 425
Megaloblastic anemia 1 | 18
Mood Disorders 1 | 184
Neoplasm Metastasis 1 | 168
Neurodegenerative disease 1 | 414
Oligospermia 1 | 36
Ollier disease 1 | 18
Polycystic ovary syndrome 1 | 360
Premature ovarian failure 1 | 65
Subcutaneous mycosis 1 | 2
Substance-Related Disorders 1 | 115
Tinea pedis 1 | 29
Transient neonatal diabetes mellitus 1 | 14
Unipolar Depression 1 | 250
Vascular disease 1 | 319
Waldenstrons macroglobulinemia 1 | 765
Williams-Beuren syndrome 1 | 50
Xeroderma pigmentosum group B 1 | 20
adrenocortical carcinoma 1 | 1,428
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
gastric carcinoma 1 | 807
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
non-small cell lung cancer 1 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Blood and immune system 27 | 16,909
Nervous System 27 | 16,725
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Liver and Pancreas 25 | 16,750
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Enzyme 17 | 4,145
Epigenetic 5 | 242
Non-IDG 5 | 12,091
Transcription Factor 1 | 1,400

Reactome Pathway

PIWI-interacting RNA (piRNA) b... 28 | 28
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
ATP-dependent RNA helicase TDRD9 TDRD9 Tbio Epigenetic -0.66287 3.88 43
DNA-directed RNA polymerases I, II, and III subunit RPABC2 POLR2F Tbio Enzyme -1.13403 13.9 68
DNA-directed RNA polymerases I, II, and III subunit RPABC4 POLR2K Tbio Enzyme -0.90716 7.36 65
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L Tbio Enzyme -1.12793 13.8 66
Putative ATP-dependent RNA helicase TDRD12 TDRD12 Tdark Epigenetic -0.70932 5.33 24
RNA helicase Mov10l1 MOV10L1 Tbio Enzyme -0.73306 5.20 57
Tudor domain-containing protein 1 TDRD1 Tbio Epigenetic -1.00874 10.4 88
Tudor domain-containing protein 6 TDRD6 Tdark Epigenetic -1.01017 7.74 9