Development Level

Tchem 9 | 1,598
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Targets) 3 | 126

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
decreased urine magnesium leve... 1 | 3
enlarged heart 1 | 210
increased total body fat amoun... 1 | 134

Disease

Carcinoma 11 | 11,493
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
ovarian cancer 3 | 8,520
primary Sjogren syndrome 3 | 735
sarcoidosis 3 | 370
subependymal giant cell astrocytoma 3 | 2,287
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Hypertrophic cardiomyopathy 20 2 | 12
Percutaneous coronary intervention 2 | 9
Thrombosis 2 | 46
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
glioblastoma 2 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Abnormality of vision 1 | 40
Afro-textured hair 1 | 13
Alopecia 1 | 115
Atrial Fibrillation 1 | 124
Brittle hair 1 | 25
Central sleep apnea 1 | 11
Coarse hair 1 | 31
Disease of mental health 1 | 36
Dry eye syndrome 1 | 18
Endometriosis 1 | 540
Excessive daytime somnolence 1 | 14
Fine hair 1 | 42
Fractured hair 1 | 25
Fragile hair 1 | 25
Gaucher disease type 3 1 | 67
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Hypotrichosis 1 | 47
Hypotrichosis 6 1 | 4
Hypotrichosis 8 1 | 6
Hypotrichosis of the scalp 1 | 6
Hypotrichosis simplex 1 | 7
Kinky hair texture 1 | 13
Lupus Erythematosus, Systemic 1 | 67
Melanoma 1 | 711
Monilethrix 1 | 18
Myocardial Infarction 1 | 151
Nappy hair texture 1 | 13
Narcolepsy 1 | 72
Neurodegeneration with brain iron accumulation 4 1 | 6
Papillary thyroid carcinoma 1 | 43
Peripheral vascular disease 1 | 87
Reduced tensile strength of hair 1 | 25
Rough hair texture 1 | 31
Sickle Cell Anemia 1 | 53
Sparse body hair 1 | 32
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Tear film insufficiency 1 | 15
Transient Cerebral Ischemia 1 | 25
Usher syndrome type 3 1 | 5
Vascular disease 1 | 319
Waldenstrons macroglobulinemia 1 | 765
Woolly hair, autosomal dominant 1 | 5
Woolly hair, congenital 1 | 5
Wooly hair 1 | 17
active ulcerative colitis 1 | 764
astrocytoma 1 | 1,146
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
inflammatory breast cancer 1 | 286
nasopharyngeal carcinoma 1 | 1,058
tuberculosis and treatment for 6 months 1 | 409
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Liver and Pancreas 10 | 16,750
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Urinary Tract 10 | 16,678

Target Family

GPCR 11 | 408

Reactome Pathway

P2Y receptors 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
P2Y purinoceptor 4 P2RY4 Tchem GPCR -1.85746 67.8 189
P2Y purinoceptor 6 P2RY6 Tchem GPCR -1.99873 102.6 191
Putative P2Y purinoceptor 10 P2RY10 Tchem GPCR -0.43532 2.47 117
P2Y purinoceptor 11 P2RY11 Tchem GPCR -2.70343 881.0 159
P2Y purinoceptor 13 P2RY13 Tchem GPCR -1.45620 26.2 236
Lysophosphatidic acid receptor 4 LPAR4 Tchem GPCR -1.38205 22.6 190
Lysophosphatidic acid receptor 6 LPAR6 Tchem GPCR -1.51557 35.0 109
P2Y purinoceptor 12 P2RY12 Tclin GPCR -3.19274 1507.4 135
P2Y purinoceptor 14 P2RY14 Tchem GPCR -1.66731 47.4 147