Development Level

Tbio 28 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal heart position or ori... 1 | 1
abnormal lung morphology 1 | 26
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased grip strength 1 | 116
embryonic lethality prior to t... 1 | 278
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 25 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 20 | 7,950
glioblastoma 17 | 5,792
lung cancer 17 | 4,740
psoriasis 17 | 6,694
adult high grade glioma 15 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
malignant mesothelioma 12 | 3,232
medulloblastoma, large-cell 12 | 6,241
Astrocytoma, Pilocytic 11 | 3,081
Cancer 11 | 2,499
subependymal giant cell astrocytoma 11 | 2,287
ulcerative colitis 11 | 1,819
tuberculosis 10 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
Atopic dermatitis 7 | 952
Breast cancer 7 | 3,578
Rheumatoid arthritis 7 | 1,191
astrocytic glioma 7 | 2,597
pancreatic cancer 7 | 2,398
Kidney cancer 6 | 2,613
acute myeloid leukemia 6 | 783
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Crohn's disease 5 | 321
Melanoma 5 | 711
Systemic lupus erythematosus 5 | 194
cutaneous lupus erythematosus 5 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
juvenile dermatomyositis 5 | 1,187
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
Asthma 4 | 385
Breast Neoplasms 4 | 445
Cell Transformation, Neoplastic 4 | 97
Endometriosis 4 | 540
Epilepsy 4 | 792
Influenza 4 | 142
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Pick disease 4 | 1,894
Seizures 4 | 596
adrenocortical carcinoma 4 | 1,428
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
Adenocarcinoma 3 | 122
Adenoma 3 | 167
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Bladder Neoplasm 3 | 112
Blau syndrome 3 | 9
Carcinoma, Hepatocellular 3 | 228
Disease Progression 3 | 136
Endometrial cancer 3 | 311
Hypertension 3 | 396
Immune system cancer 3 | 140
Intellectual disability 3 | 1,016
Liver carcinoma 3 | 240
Lung disease 3 | 142
Lupus Erythematosus, Systemic 3 | 67
Lymphoid leukemia 3 | 160
Lymphoma, T-Cell, Cutaneous 3 | 22
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Neoplasm Invasiveness 3 | 161
Neoplasm Metastasis 3 | 168
Neoplastic Cell Transformation 3 | 89
Neurodegenerative disease 3 | 414
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Urinary Bladder Neoplasms 3 | 114
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
X-linked lymphoproliferative syndrome 2 3 | 4
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
hepatocellular carcinoma 3 | 547
progressive supranuclear palsy 3 | 676
sarcoidosis 3 | 370
Adenoid Cystic Carcinoma 2 | 99
Myopathy 2 | 185
Skin cancer 2 | 469

Tissue

Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 12 | 4,145
Kinase 4 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Reactome Pathway

Ovarian tumor domain proteases 37 | 37
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin thioesterase OTU1 YOD1 Tbio Enzyme -1.63573 39.8 111
OTU domain-containing protein 7A OTUD7A Tbio Non-IDG -0.54041 3.76 78
Ubiquitin thioesterase OTUB2 OTUB2 Tbio Enzyme -1.01946 11.0 252
Ubiquitin thioesterase OTUB1 OTUB1 Tbio Enzyme -1.68151 50.0 281
OTU domain-containing protein 5 OTUD5 Tbio Non-IDG -0.89861 6.92 100