Development Level

Tdark 410 | 7,003
Tbio 19 | 10,625
Tchem 1 | 1,890

Disease

diabetes mellitus 71 | 1,663
osteosarcoma 28 | 7,933
medulloblastoma, large-cell 24 | 6,234
ovarian cancer 24 | 8,492
psoriasis 17 | 6,685
adult high grade glioma 14 | 2,148
Hemolytic anemia 12 | 70
Carcinoma 11 | 2,147
atypical teratoid / rhabdoid tumor 9 | 4,369
glioblastoma 7 | 5,572
lung adenocarcinoma 7 | 2,714
lung carcinoma 7 | 2,844
non primary Sjogren syndrome sicca 6 | 840
Breast cancer 5 | 3,099
Rheumatoid Arthritis 5 | 1,171
ependymoma 5 | 2,514
malignant mesothelioma 5 | 3,163
Anorexia nervosa 4 | 59
Pick disease 4 | 1,893
Sickle Cell Anemia 4 | 54
Thalassemia 4 | 46
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
pancreatic cancer 4 | 2,300
Multiple Sclerosis 3 | 498
Type 1 diabetes mellitus 3 | 104
colon cancer 3 | 1,475
ductal carcinoma in situ 3 | 1,745
lung cancer 3 | 4,473
medulloblastoma 3 | 1,524
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,271
primitive neuroectodermal tumor 3 | 3,031
sonic hedgehog group medulloblastoma 3 | 1,482
Acquired metabolic disease 2 | 267
Anxiety Disorders 2 | 37
Atopic dermatitis 2 | 944
Beta thalassemia 2 | 19
Cardiovascular system disease 2 | 194
Chronic obstructive pulmonary disease 2 | 147
Infertility 2 | 163
Juvenile rheumatoid arthritis 2 | 105
Malaria 2 | 140
Multiple myeloma 2 | 1,328
Neurodegenerative disease 2 | 383
Paraplegia 2 | 71
Peripheral vascular disease 2 | 90
Prostate cancer 2 | 172
Pulmonary edema 2 | 14
astrocytoma 2 | 1,493
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,670
group 4 medulloblastoma 2 | 1,875
hereditary spastic paraplegia 2 | 313
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
non diabetic and post-ischemic heart failure 2 | 200
non-small cell lung cancer 2 | 2,798
non-small cell lung carcinoma 2 | 413
oligodendroglioma 2 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
urothelial carcinoma 2 | 318
Amenorrhea 1 | 60
Amyotrophic Lateral Sclerosis 1 | 432
Atrophic gastritis 1 | 5
Autistic Disorder 1 | 320
Azoospermia 1 | 89
Bladder Neoplasm 1 | 109
Charcot-Marie-Tooth disease 1 | 74
Chromosome 18p deletion syndrome 1 | 5
Colorectal adenoma 1 | 15
Depressive disorder 1 | 48
Disease of anatomical entity 1 | 25
Distal arthrogryposis 1 | 45
Dystonia 1 | 77
Globe disease 1 | 57
Gout 1 | 93
Hereditary hemorrhagic telangiectasia 1 | 14
Influenza 1 | 142
Liver carcinoma 1 | 217
Liver neoplasms 1 | 109
Lymphoma 1 | 57
Major Depressive Disorder 1 | 106
Mastitis 1 | 48
Narcolepsy 1 | 69
Neuropathy 1 | 210
Pain agnosia 1 | 99
Pineoblastoma 1 | 7
Prader-Willi syndrome 1 | 45
Renal Cell Carcinoma 1 | 199
Retinitis pigmentosa 1 | 156
Substance-Related Disorders 1 | 114
Telangiectasis 1 | 20
active ulcerative colitis 1 | 477
glioblastoma multiforme 1 | 347
post-traumatic stress disorder 1 | 45

Tissue

Female tissues 330 | 18,647
Urinary Tract 306 | 18,444
Endocrine System 251 | 18,512
Nervous System 247 | 18,561
Digestive Tract 225 | 18,473
Skin and soft tissues 194 | 18,115
Liver and Pancreas 136 | 18,136
Blood and immune system 127 | 17,995
Cardiovascular System 115 | 17,958
Male tissues 95 | 17,969
Respiratory system 70 | 17,484

Target Family

oGPCR 416 | 421
Non-IDG 14 | 11,969

Reactome Pathway

Olfactory Signaling Pathway 430 | 430
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Olfactory receptor 6C6 OR6C6 Tdark oGPCR 0.00000 24
Olfactory receptor 2W1 OR2W1 Tdark oGPCR 0.15 0.39 63
Olfactory receptor 2T8 OR2T8 Tdark oGPCR 0.00000 44
Receptor expression-enhancing protein 2 REEP2 Tdark Non-IDG -0.37718 2.82 80
Receptor-transporting protein 3 RTP3 Tbio Non-IDG -0.87795 7.79 31
Guanine nucleotide-binding protein G(olf) subunit alpha GNAL Tbio Non-IDG -1.46688 28.8 86
Receptor expression-enhancing protein 5 REEP5 Tbio Non-IDG -2.36759 214.6 144
Olfactory receptor 5K3 OR5K3 Tdark oGPCR 1.11 0.04 28
Olfactory receptor 2A25 OR2A25 Tdark oGPCR 0.00000 38
Olfactory receptor 10J1 OR10J1 Tdark oGPCR 0.00000 38