Development Level

Tbio 46 | 10,625
Tdark 14 | 7,003
Tchem 6 | 1,890

IMPC Phenotype

increased exploration in new e... 2 | 56
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
enlarged heart 1 | 111
enlarged spleen 1 | 26
increased Ly6C high monocyte n... 1 | 12
increased circulating fructosa... 1 | 11
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
short tibia 1 | 82

Disease

ovarian cancer 32 | 8,491
osteosarcoma 26 | 7,933
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
lung adenocarcinoma 25 | 2,714
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
psoriasis 24 | 6,685
pancreatic cancer 19 | 2,300
Breast cancer 18 | 3,098
cystic fibrosis 16 | 1,670
glioblastoma 16 | 5,572
medulloblastoma, large-cell 16 | 6,234
pilocytic astrocytoma 16 | 3,086
pituitary cancer 16 | 1,972
lung cancer 13 | 4,473
invasive ductal carcinoma 12 | 2,950
nasopharyngeal carcinoma 12 | 1,056
active Crohn's disease 11 | 918
atypical teratoid / rhabdoid tumor 11 | 4,369
Carcinoma 10 | 2,147
malignant mesothelioma 10 | 3,163
non-small cell lung cancer 10 | 2,798
posterior fossa group A ependymoma 10 | 1,511
ulcerative colitis 10 | 2,087
Cancer 9 | 2,346
breast carcinoma 9 | 1,614
interstitial cystitis 9 | 2,299
oligodendroglioma 9 | 2,849
primitive neuroectodermal tumor 9 | 3,031
astrocytic glioma 8 | 2,241
ductal carcinoma in situ 8 | 1,745
group 3 medulloblastoma 8 | 2,254
group 4 medulloblastoma 8 | 1,875
lung carcinoma 8 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
pediatric high grade glioma 8 | 2,712
spina bifida 8 | 1,064
Atopic dermatitis 7 | 944
esophageal adenocarcinoma 7 | 737
active ulcerative colitis 6 | 477
adult high grade glioma 6 | 2,148
atypical teratoid/rhabdoid tumor 6 | 1,095
diabetes mellitus 6 | 1,663
posterior fossa group B ependymoma 6 | 1,530
IGA Glomerulonephritis 5 | 454
Multiple myeloma 5 | 1,327
colon cancer 5 | 1,475
non primary Sjogren syndrome sicca 5 | 840
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 165
Biliary papillomatosis 4 | 4
Otitis media 4 | 32
Rheumatoid Arthritis 4 | 1,170
astrocytoma 4 | 1,493
cutaneous lupus erythematosus 4 | 1,056
facioscapulohumeral dystrophy 4 | 286
gastric carcinoma 4 | 832
interstitial lung disease 4 | 292
non-small cell lung carcinoma 4 | 413
pancreatic carcinoma 4 | 567
primary pancreatic ductal adenocarcinoma 4 | 1,271
Amyotrophic Lateral Sclerosis 3 | 432
Asthma 3 | 349
Bilateral breast cancer 3 | 4
Gastritis 3 | 44
Pick disease 3 | 1,893
Prostatic Neoplasms 3 | 471
Systemic scleroderma 3 | 66
Waldenstrons macroglobulinemia 3 | 764
adrenocortical carcinoma 3 | 1,427
chronic rhinosinusitis 3 | 512
ependymoma 3 | 2,514
fibroadenoma 3 | 557
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
primary Sjogren syndrome 3 | 788
sonic hedgehog group medulloblastoma 3 | 1,482
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 267
Alzheimer's disease 2 | 644
Barrett's esophagus 2 | 185
Bronchitis 2 | 44
Chronic obstructive pulmonary disease 2 | 147
Common cold 2 | 63
Influenza 2 | 142
Multiple Sclerosis 2 | 498
Pneumonia 2 | 133
Primary ciliary dyskinesia 2 | 75
Stomach Neoplasms 2 | 282
Type 2 diabetes mellitus 2 | 192
Williams-Beuren syndrome 2 | 45
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
dermatomyositis 2 | 966
inflammatory breast cancer 2 | 404
periodontitis 2 | 269
tuberculosis 2 | 1,563
tuberculosis and treatment for 6 months 2 | 686
uncontrolled asthma 2 | 67

Tissue

Digestive Tract 63 | 18,472
Liver and Pancreas 63 | 18,135
Urinary Tract 63 | 18,443
Cardiovascular System 62 | 17,957
Endocrine System 62 | 18,511
Female tissues 62 | 18,646
Male tissues 62 | 17,968
Nervous System 62 | 18,560
Respiratory system 62 | 17,483
Skin and soft tissues 62 | 18,114
Blood and immune system 61 | 17,994

Target Family

Enzyme 48 | 4,146
Non-IDG 18 | 11,969

Reactome Pathway

O-linked glycosylation of muci... 66 | 66
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

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