Development Level

Tbio 24 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613

IMPC Phenotype

abnormal epididymis morphology 2 | 42
decreased mean corpuscular vol... 2 | 79
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart 1 | 210
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 19 | 11,493
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 15 | 7,950
psoriasis 15 | 6,694
glioblastoma 13 | 5,792
Autosomal recessive predisposition 12 | 1,442
lung cancer 12 | 4,740
ependymoma 11 | 4,679
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Cancer 9 | 2,499
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pancreatic cancer 8 | 2,398
tuberculosis 8 | 2,010
Astrocytoma, Pilocytic 7 | 3,081
interstitial cystitis 7 | 2,312
Breast cancer 6 | 3,578
Schizophrenia 6 | 1,160
adult high grade glioma 6 | 3,801
cutaneous lupus erythematosus 6 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
astrocytic glioma 5 | 2,597
gastric carcinoma 5 | 807
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
Autistic Disorder 4 | 364
Epilepsy 4 | 792
Obesity 4 | 678
Vascular disease 4 | 319
cystic fibrosis 4 | 1,696
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
malignant mesothelioma 4 | 3,232
pediatric high grade glioma 4 | 1,064
Anemia 3 | 365
Atopic dermatitis 3 | 952
Colorectal Neoplasms 3 | 243
Endometriosis 3 | 540
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Motor delay 3 | 147
No development of motor milestones 3 | 147
Osteoporosis 3 | 363
Stomach Neoplasms 3 | 300
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Autism spectrum disorder 2 | 101
Bipolar Disorder 2 | 666
Colonic Neoplasms 2 | 142
Delayed speech and language development 2 | 112
Failure to gain weight 2 | 365
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Language Delay 2 | 112
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Pick disease 2 | 1,894
Recurrence 2 | 33
Reperfusion Injury 2 | 86
Seizures 2 | 596
Skin cancer 2 | 469
Speech Delay 2 | 112
Speech impairment 2 | 112
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
atypical teratoid/rhabdoid tumor 2 | 357
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
posterior fossa group B ependymoma 2 | 416

Tissue

Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Endocrine System 34 | 18,159
Male tissues 34 | 17,142
Blood and immune system 33 | 16,909
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Cardiovascular System 29 | 15,192

Target Family

Enzyme 34 | 4,145
Non-IDG 1 | 12,091

Reactome Pathway

Nucleobase catabolism 35 | 35
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ectonucleoside triphosphate diphosphohydrolase 2 ENTPD2 Tchem Enzyme -2.37613 245.8 150
Nucleotide triphosphate diphosphatase NUDT15 NUDT15 Tbio Enzyme -1.60299 37.9 77
Cytosolic 5'-nucleotidase 1B NT5C1B Tbio Enzyme -1.94015 85.4 93
Guanine deaminase GDA Tbio Enzyme -1.48687 32.3 196
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 DNPH1 Tchem Enzyme -2.27742 184.2 151
Cytosolic 5'-nucleotidase 1A NT5C1A Tbio Enzyme -2.15798 140.3 139
Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 Tbio Enzyme -1.47858 32.0 77
Ectonucleoside triphosphate diphosphohydrolase 8 ENTPD8 Tbio Enzyme -1.64543 43.5 116
Cytosolic purine 5'-nucleotidase NT5C2 Tbio Enzyme -2.24348 166.8 144