Development Level

Tbio 102 | 10,625
Tdark 9 | 7,003
Tchem 6 | 1,890

IMPC Phenotype

preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 46 | 8,491
lung cancer 36 | 4,473
diabetes mellitus 28 | 1,663
medulloblastoma, large-cell 28 | 6,234
Multiple myeloma 27 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
Diamond-Blackfan anemia 24 | 30
osteosarcoma 23 | 7,933
psoriasis 20 | 6,685
acute quadriplegic myopathy 17 | 1,157
Waldenstrons macroglobulinemia 16 | 764
sonic hedgehog group medulloblastoma 16 | 1,482
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
glioblastoma 14 | 5,572
Anemia, Diamond-Blackfan 13 | 15
Breast cancer 12 | 3,098
astrocytoma 12 | 1,493
malignant mesothelioma 12 | 3,163
atypical teratoid / rhabdoid tumor 11 | 4,369
group 3 medulloblastoma 11 | 2,254
cystic fibrosis 10 | 1,670
oligodendroglioma 10 | 2,849
Disease Progression 9 | 125
Stomach Neoplasms 9 | 282
acute myeloid leukemia 9 | 785
lung adenocarcinoma 9 | 2,714
inflammatory breast cancer 8 | 404
invasive ductal carcinoma 8 | 2,950
non-small cell lung cancer 8 | 2,798
Anemia 7 | 252
Cancer 7 | 2,346
Mammary Neoplasms 7 | 410
mucosa-associated lymphoid tissue lymphoma 7 | 480
subependymal giant cell astrocytoma 7 | 2,287
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
Carcinoma 5 | 2,147
adult high grade glioma 5 | 2,148
aldosterone-producing adenoma 5 | 664
ependymoma 5 | 2,514
pediatric high grade glioma 5 | 2,712
primitive neuroectodermal tumor 5 | 3,031
Amyotrophic Lateral Sclerosis 4 | 432
Duchenne muscular dystrophy 4 | 602
Parkinson Disease 4 | 105
Pick disease 4 | 1,893
Polycystic Ovary Syndrome 4 | 334
Rheumatoid Arthritis 4 | 1,170
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
glioblastoma multiforme 4 | 347
group 4 medulloblastoma 4 | 1,875
juvenile dermatomyositis 4 | 1,189
lung carcinoma 4 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 6 months 4 | 686
Animal Mammary Neoplasms 3 | 135
Bowen-Conradi syndrome 3 | 16
Intellectual disability 3 | 573
Irregular astigmatism 3 | 11
Mammary Neoplasms, Experimental 3 | 149
Osteoporosis 3 | 259
Prostatic Neoplasms 3 | 471
Pure red-cell aplasia 3 | 4
Weight Gain 3 | 87
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 966
hereditary spastic paraplegia 3 | 313
primary pancreatic ductal adenocarcinoma 3 | 1,271
spina bifida 3 | 1,064
Acquired immunodeficiency syndrome 2 | 164
Acquired metabolic disease 2 | 267
Anoxia 2 | 33
Autistic Disorder 2 | 320
Babesiosis 2 | 13
Brucellosis 2 | 24
Lymphoid leukemia 2 | 69
Microcephaly 2 | 149
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 127
Ovarian Cysts 2 | 34
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2 | 18
Schizophrenia 2 | 503
Shwachman-Diamond syndrome 2 | 16
Spondylosis 2 | 13
Theileriasis 2 | 13
Treacher Collins syndrome 2 | 29
Turner syndrome 2 | 31
Tyrosinemia type I 2 | 4
Ullrich congenital muscular dystrophy 2 | 7
active Crohn's disease 2 | 918
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 117 | 17,994
Cardiovascular System 117 | 17,957
Digestive Tract 117 | 18,472
Endocrine System 117 | 18,511
Female tissues 117 | 18,646
Liver and Pancreas 117 | 18,135
Male tissues 117 | 17,968
Nervous System 117 | 18,560
Urinary Tract 117 | 18,443
Respiratory system 116 | 17,483
Skin and soft tissues 113 | 18,114

Target Family

Non-IDG 109 | 11,969
Enzyme 7 | 4,146
Kinase 1 | 634

Reactome Pathway

Nonsense-Mediated Decay (NMD) 117 | 117
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase SMG1 SMG1 Tchem Kinase -1.58792 56.8 175
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.12258 1305.7 243
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.31776 194.4 161
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.62587 63.2 46
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.83618 67.7 104
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39373 24.2 45
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.27308 14.5 115
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.89981 78.2 62
60S acidic ribosomal protein P1 RPLP1 Tbio Non-IDG -1.22833 29.8 76
60S acidic ribosomal protein P2 RPLP2 Tbio Non-IDG -2.23919 29.8 129