Development Level

Tbio 102 | 10,625
Tdark 9 | 7,003
Tchem 6 | 1,890

IMPC Term

preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 46 | 8,484
lung cancer 36 | 4,466
diabetes mellitus 28 | 1,663
medulloblastoma, large-cell 28 | 6,234
Multiple myeloma 27 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
Diamond-Blackfan anemia 23 | 28
osteosarcoma 23 | 7,933
psoriasis 20 | 6,685
acute quadriplegic myopathy 17 | 1,157
Waldenstrons macroglobulinemia 16 | 765
sonic hedgehog group medulloblastoma 16 | 1,482
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
glioblastoma 14 | 5,572
Anemia, Diamond-Blackfan 13 | 15
Breast cancer 12 | 3,094
astrocytoma 12 | 1,493
malignant mesothelioma 12 | 3,162
atypical teratoid / rhabdoid tumor 11 | 4,369
group 3 medulloblastoma 11 | 2,254
cystic fibrosis 10 | 1,665
oligodendroglioma 10 | 2,849
Disease Progression 9 | 125
Stomach Neoplasms 9 | 282
acute myeloid leukemia 9 | 780
lung adenocarcinoma 9 | 2,713
inflammatory breast cancer 8 | 404
invasive ductal carcinoma 8 | 2,950
non-small cell lung cancer 8 | 2,798
Anemia 7 | 252
Cancer 7 | 2,346
Mammary Neoplasms 7 | 410
mucosa-associated lymphoid tissue lymphoma 7 | 480
subependymal giant cell astrocytoma 7 | 2,287
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
Carcinoma 5 | 2,147
adult high grade glioma 5 | 2,148
aldosterone-producing adenoma 5 | 664
ependymoma 5 | 2,514
pediatric high grade glioma 5 | 2,712
primitive neuroectodermal tumor 5 | 3,031
Amyotrophic Lateral Sclerosis 4 | 431
Duchenne muscular dystrophy 4 | 602
Parkinson Disease 4 | 102
Pick disease 4 | 1,893
Polycystic Ovary Syndrome 4 | 332
Rheumatoid Arthritis 4 | 1,160
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
glioblastoma multiforme 4 | 347
group 4 medulloblastoma 4 | 1,875
juvenile dermatomyositis 4 | 1,189
lung carcinoma 4 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 6 months 4 | 686
Animal Mammary Neoplasms 3 | 136
Bowen-Conradi syndrome 3 | 16
Intellectual disability 3 | 573
Irregular astigmatism 3 | 11
Mammary Neoplasms, Experimental 3 | 150
Osteoporosis 3 | 257
Prostatic Neoplasms 3 | 471
Pure red-cell aplasia 3 | 4
Weight Gain 3 | 87
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 933
hereditary spastic paraplegia 3 | 313
primary pancreatic ductal adenocarcinoma 3 | 1,271
spina bifida 3 | 1,064
Acquired immunodeficiency syndrome 2 | 164
Acquired metabolic disease 2 | 267
Anoxia 2 | 33
Autistic Disorder 2 | 320
Babesiosis 2 | 13
Brucellosis 2 | 24
Lymphoid leukemia 2 | 69
Microcephaly 2 | 149
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 127
Ovarian Cysts 2 | 34
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2 | 18
Schizophrenia 2 | 501
Shwachman-Diamond syndrome 2 | 16
Spondylosis 2 | 13
Theileriasis 2 | 13
Treacher Collins syndrome 2 | 29
Turner syndrome 2 | 31
Tyrosinemia type I 2 | 3
Ullrich congenital muscular dystrophy 2 | 7
active Crohn's disease 2 | 918
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 117 | 17,995
Cardiovascular System 117 | 17,958
Digestive Tract 117 | 18,473
Endocrine System 117 | 18,512
Female tissues 117 | 18,647
Liver and Pancreas 117 | 18,136
Male tissues 117 | 17,969
Nervous System 117 | 18,561
Urinary Tract 117 | 18,444
Respiratory system 116 | 17,484
Skin and soft tissues 113 | 18,115

Target Family

Non-IDG 109 | 11,971
Enzyme 7 | 4,146
Kinase 1 | 634

Reactome Pathway

Nonsense-Mediated Decay (NMD) 117 | 117
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein SMG5 SMG5 Tbio Non-IDG -0.98094 8.29 78
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60
60S ribosomal protein L18 RPL18 Tbio Non-IDG -1.73537 50.7 134
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45
Eukaryotic peptide chain release factor subunit 1 ETF1 Tbio Enzyme -1.69308 48.0 90
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.29353 14.5 115
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
40S ribosomal protein S4, Y isoform 1 RPS4Y1 Tbio Non-IDG -1.22796 15.4 118
60S ribosomal protein L8 RPL8 Tbio Non-IDG -1.56871 36.4 182
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207