Development Level

Tbio 30 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased circulating choleste... 3 | 93
decreased lymphocyte cell numb... 3 | 83
impaired glucose tolerance 3 | 75
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal locomotor behavior 2 | 24
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased pulmonary respirator... 2 | 5
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
enlarged stomach 2 | 2
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
small thymus 2 | 16
abnormal behavior 1 | 298
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
limb grasping 1 | 41
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 36 | 11,493
ovarian cancer 29 | 8,520
glioblastoma 28 | 5,792
Breast cancer 24 | 3,578
psoriasis 24 | 6,694
lung carcinoma 23 | 2,843
Kidney cancer 22 | 2,613
malignant mesothelioma 22 | 3,232
pancreatic cancer 22 | 2,398
atypical teratoid / rhabdoid tumor 21 | 5,112
lung cancer 21 | 4,740
medulloblastoma, large-cell 21 | 6,241
Cancer 20 | 2,499
invasive ductal carcinoma 19 | 2,951
osteosarcoma 19 | 7,950
ependymoma 18 | 4,679
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
cystic fibrosis 16 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
non-small cell lung cancer 16 | 2,890
lung adenocarcinoma 15 | 2,716
Autosomal recessive predisposition 14 | 1,442
primary pancreatic ductal adenocarcinoma 13 | 1,109
Schizophrenia 12 | 1,160
ductal carcinoma in situ 12 | 1,745
group 3 medulloblastoma 12 | 4,104
adult high grade glioma 11 | 3,801
breast carcinoma 11 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Duchenne muscular dystrophy 10 | 601
interstitial cystitis 10 | 2,312
nasopharyngeal carcinoma 10 | 1,058
primitive neuroectodermal tumor 10 | 3,035
tuberculosis 10 | 2,010
active ulcerative colitis 9 | 764
astrocytoma 9 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
oligodendroglioma 9 | 2,850
ulcerative colitis 9 | 1,819
Intellectual disability 8 | 1,016
Liver cancer 8 | 604
diabetes mellitus 8 | 1,728
esophageal adenocarcinoma 8 | 737
Epilepsy 7 | 792
Muscle hypotonia 7 | 571
Myopia 7 | 176
Prenatal onset 7 | 139
Prostatic Neoplasms 7 | 495
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
colon cancer 7 | 1,478
dermatomyositis 7 | 966
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Endometrial cancer 6 | 311
Kidney disease 6 | 430
Myopathy 6 | 185
Seizures 6 | 596
fibroadenoma 6 | 559
gastric carcinoma 6 | 807
pediatric high grade glioma 6 | 1,064
ANONYCHIA 5 | 20
Acquired scoliosis 5 | 281
Anemia 5 | 365
Aplasia Cutis Congenita 5 | 14
Arthritis 5 | 290
Atopic dermatitis 5 | 952
Atrophic scar 5 | 18
Congenital scar 5 | 13
Curvature of spine 5 | 282
Death in early childhood 5 | 82
Death in infancy 5 | 82
Dental Enamel Hypoplasia 5 | 43
Dental caries 5 | 164
Depressive disorder 5 | 409
Down syndrome 5 | 499
Dull intelligence 5 | 645
Dystrophia unguium 5 | 53
Endometriosis 5 | 540
Epidermolysis bullosa 5 | 21
Gliosis 5 | 56
Heart disease 5 | 306
Hemoglobin low 5 | 124
Liver Cirrhosis 5 | 181
Liver Cirrhosis, Experimental 5 | 769
Low intelligence 5 | 645
Melanoma 5 | 711
Mental deficiency 5 | 645
Muscle Weakness 5 | 170
Nail dysplasia 5 | 52
Poor school performance 5 | 645
Rotting teeth 5 | 73
acute quadriplegic myopathy 5 | 1,158
cutaneous lupus erythematosus 5 | 1,057
medulloblastoma 5 | 720

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 35 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

Reactome Pathway

Non-integrin membrane-ECM inte... 42 | 42
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.26801 0.00000 534
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.12297 152.1 302
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Tenascin TNC Tbio Non-IDG -2.34421 216.5 642
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704