Development Level

Tbio 27 | 11,445
Tchem 17 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
head bobbing 1 | 5
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 37 | 11,493
medulloblastoma, large-cell 33 | 6,241
glioblastoma 32 | 5,792
atypical teratoid / rhabdoid tumor 31 | 5,112
adult high grade glioma 30 | 3,801
ependymoma 28 | 4,679
Astrocytoma, Pilocytic 27 | 3,081
Schizophrenia 27 | 1,160
group 3 medulloblastoma 26 | 4,104
oligodendroglioma 25 | 2,850
primitive neuroectodermal tumor 24 | 3,035
astrocytic glioma 23 | 2,597
ovarian cancer 23 | 8,520
psoriasis 20 | 6,694
osteosarcoma 19 | 7,950
Pick disease 18 | 1,894
subependymal giant cell astrocytoma 17 | 2,287
Epilepsy 16 | 792
lung carcinoma 16 | 2,843
Bipolar Disorder 15 | 666
lung cancer 15 | 4,740
malignant mesothelioma 14 | 3,232
Parkinson's disease 13 | 392
Alzheimer's disease 12 | 658
Seizures 11 | 596
pituitary cancer 11 | 1,972
Depressive disorder 10 | 409
Mental Depression 10 | 333
Kidney cancer 9 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Autistic Disorder 7 | 364
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Major Depressive Disorder 7 | 301
Mental and motor retardation 7 | 608
Toxic encephalopathy 7 | 141
pancreatic cancer 7 | 2,398
Alcoholic Intoxication, Chronic 6 | 289
Amyotrophic lateral sclerosis 6 | 451
Breast cancer 6 | 3,578
Intellectual disability 6 | 1,016
Unipolar Depression 6 | 250
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
invasive ductal carcinoma 6 | 2,951
Attention deficit hyperactivity disorder 5 | 278
Cancer 5 | 2,499
Dementia 5 | 175
Glaucoma 5 | 239
Mood Disorders 5 | 184
Obesity 5 | 678
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
Blepharoptosis 4 | 231
Cerebellar Ataxia 4 | 304
Congenital Myasthenic Syndromes, Presynaptic 4 | 8
Congenital myasthenic syndrome 4 | 25
Down syndrome 4 | 499
Huntington's disease 4 | 76
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
Neurodevelopmental Disorders 4 | 70
Psychotic Disorders 4 | 151
Rheumatoid arthritis 4 | 1,191
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
nephrosclerosis 4 | 333
tuberculosis 4 | 2,010
Abnormal behavior 3 | 52
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cocaine-Related Disorders 3 | 92
Dull intelligence 3 | 645
Dysarthria 3 | 192
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Small head 3 | 374
Status Epilepticus 3 | 98
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
diabetes mellitus 3 | 1,728
ulcerative colitis 3 | 1,819

Tissue

Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Nervous System 48 | 16,725
Skin and soft tissues 48 | 17,230
Female tissues 47 | 17,400
Male tissues 47 | 17,142
Liver and Pancreas 46 | 16,750
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Respiratory system 43 | 16,393
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 23 | 12,091
Transporter 17 | 473
Enzyme 9 | 4,145
Kinase 1 | 634

Reactome Pathway

Neurotransmitter release cycle 50 | 50
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Glutaminase kidney isoform, mitochondrial GLS Tchem Enzyme -2.92171 795.3 268
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Excitatory amino acid transporter 4 SLC1A6 Tchem Transporter -1.89314 75.8 107
Succinate-semialdehyde dehydrogenase, mitochondrial ALDH5A1 Tclin Enzyme -2.23586 168.4 347
Sodium- and chloride-dependent GABA transporter 3 SLC6A11 Tbio Transporter -2.26927 175.1 75
Sodium- and chloride-dependent betaine transporter SLC6A12 Tchem Transporter -2.34582 212.0 104
Peripheral-type benzodiazepine receptor-associated protein 1 TSPOAP1 Tbio Non-IDG -0.53932 4.30 18