Development Level

Tclin 6 | 613
Tbio 2 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
Bipolar Disorder 6 | 666
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
Dementia 5 | 175
Obesity 5 | 678
Parkinson's disease 5 | 392
Substance abuse 5 | 59
malignant mesothelioma 5 | 3,232
Alcohol abuse 4 | 50
Alzheimer's disease 4 | 658
Attention deficit hyperactivity disorder 4 | 278
Cocaine Dependence 4 | 51
Cocaine-Related Disorders 4 | 92
Cognition Disorders 4 | 32
Conduct disorder 4 | 33
Depressive disorder 4 | 409
Heroin dependence 4 | 30
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
Mood Disorders 4 | 184
Schizophrenia 4 | 1,160
Toxic encephalopathy 4 | 141
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
Alcoholic Intoxication 3 | 34
Alcoholism 3 | 45
Amphetamine-Related Disorders 3 | 74
Anhedonia 3 | 27
Autistic Disorder 3 | 364
Constipation 3 | 181
Depression, Bipolar 3 | 12
Gilles de la Tourette syndrome 3 | 47
Memory Disorders 3 | 40
Nicotine dependence 3 | 54
Oppositional defiant disorder 3 | 17
Personality disorder 3 | 25
Unipolar Depression 3 | 250
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
obsessive-compulsive disorder 3 | 61
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Affective Disorders, Psychotic 2 | 6
Agoraphobia 2 | 21
Anxiety Disorders 2 | 38
Attention Deficit Disorder with Hyperactivity 2 | 21
Atypical depressive disorder 2 | 6
Autosomal recessive nonsyndromic deafness 63 2 | 10
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cocaine abuse 2 | 19
Cognitive delay 2 | 608
Dyschezia 2 | 135
Dysthymic Disorder 2 | 17
Eating disorder 2 | 26
Fibromyalgia 2 | 19
Gingivitis 2 | 29
Global developmental delay 2 | 608
Hodgkin's lymphoma, nodular sclerosis 2 | 22
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Hypertension 2 | 396
Kidney disease 2 | 430
Mammary Neoplasms 2 | 425
Marijuana Abuse 2 | 31
Melancholia 2 | 10
Mental and motor retardation 2 | 608
Migraine 2 | 83
Mouth Infection Prevention 2 | 5
Nonsyndromic deafness 2 | 142
Opiate dependence 2 | 29
Panic disorder 2 | 61
Parkinson Disease 2 | 64
Pathological gambling 2 | 15
Pheochromocytoma 2 | 24
Poisoning 2 | 16
Schizoaffective Disorder 2 | 55
Seasonal affective disorder 2 | 28
Severe major depression with psychotic features 2 | 9
Sudden infant death syndrome 2 | 32
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nephrosclerosis 2 | 333
pituitary cancer 2 | 1,972
post-traumatic stress disorder 2 | 40
substance-related disorder 2 | 162

Tissue

Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Respiratory system 7 | 16,393

Target Family

Enzyme 5 | 4,145
Transporter 4 | 473
Non-IDG 1 | 12,091

Reactome Pathway

Neurotransmitter clearance 10 | 10
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme -0.92913 14.1 37
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Solute carrier family 22 member 1 SLC22A1 Tchem Transporter -2.16768 152.4 206
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
Solute carrier family 22 member 2 SLC22A2 Tchem Transporter -2.15498 137.2 183
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Leucine-rich repeat-containing protein 51 LRTOMT Tbio Non-IDG -0.92913 14.1 37
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.39309 2492.1 292
Cholinesterase BCHE Tclin Enzyme -3.34790 2272.5 276
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470