Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

Disease

Carcinoma 3 | 11,493
Cancer 2 | 2,499
Robinow Syndrome, Autosomal Dominant 2 | 3
Robinow syndrome 2 | 11
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Accessory kidney 1 | 5
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anteverted nostril 1 | 191
Autosomal dominant Robinow syndrome 1 1 | 15
Bifid distal phalanx of toe 1 | 3
Bifid terminal phalanges 1 | 3
Big calvaria 1 | 147
Brachydactyly 1 | 156
Broad flat nasal bridge 1 | 236
Broad thumbs 1 | 28
Broad toes 1 | 5
Clitoral hypoplasia 1 | 11
Cognitive delay 1 | 608
Congenital clinodactyly 1 | 57
Congenital hypoplasia of penis 1 | 176
Curvature of digit 1 | 57
Decreased projection of midface 1 | 105
Delayed bone age 1 | 136
Downward slant of palpebral fissure 1 | 158
Dull intelligence 1 | 645
Exophthalmos 1 | 112
Flat face 1 | 52
Frontal bossing 1 | 157
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Global developmental delay 1 | 608
Hernia, Inguinal 1 | 89
High forehead 1 | 102
Hydronephrosis 1 | 89
Hypoplastic mandible condyle 1 | 275
Hypoplastic palate 1 | 4
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Inadequate arch length for tooth size 1 | 45
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Late tooth eruption 1 | 61
Long palpebral fissure 1 | 17
Long philtrum 1 | 137
Low intelligence 1 | 645
Macroglossia 1 | 65
Malar flattening 1 | 129
Malocclusion 1 | 57
Mandibular hypoplasia 1 | 275
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Mesomelia 1 | 8
Micrognathism 1 | 275
Midface retrusion 1 | 105
Nasal bridge wide 1 | 236
Pectus excavatum 1 | 100
Poor school performance 1 | 645
Port-Wine Stain 1 | 8
Posteriorly rotated ear 1 | 61
Prenatal onset 1 | 139
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Radially deviated fingers 1 | 38
Short distal phalanges 1 | 50
Short hands 1 | 50
Short hard palate 1 | 4
Short middle phalanx of the 5th finger 1 | 13
Short nose 1 | 132
Short palate 1 | 4
Small labia majora 1 | 16
Small midface 1 | 105
Small nose 1 | 132
Tall forehead 1 | 102
Thin upper lip vermilion 1 | 67
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Triangular mouth 1 | 6
Umbilical hernia 1 | 93
Ventricular Outflow Obstruction, Right 1 | 3
Wide anterior fontanel 1 | 44
astrocytoma 1 | 1,146
glioblastoma 1 | 5,792
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
spina bifida 1 | 1,074

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091

Reactome Pathway

Negative regulation of TCF-dep... 4 | 4
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CXXC-type zinc finger protein 4 CXXC4 Tbio Non-IDG -0.95243 9.73 0
Segment polarity protein dishevelled homolog DVL-2 DVL2 Tbio Non-IDG -1.87063 68.4 288
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169
Segment polarity protein dishevelled homolog DVL-3 DVL3 Tbio Non-IDG -1.54019 31.2 206