Development Level

Tbio 14 | 11,178
Tchem 5 | 1,885
Tclin 1 | 612

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal skin condition 1 | 6
abnormal tail morphology 1 | 25
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 14 | 11,192
ovarian cancer 14 | 8,297
medulloblastoma, large-cell 11 | 6,086
osteosarcoma 11 | 7,766
Cancer 9 | 2,388
glioblastoma 9 | 5,635
lung cancer 8 | 4,607
malignant mesothelioma 8 | 3,135
oligodendroglioma 8 | 2,768
psoriasis 8 | 6,514
astrocytic glioma 7 | 2,530
ependymoma 7 | 4,559
non-small cell lung cancer 7 | 2,799
atypical teratoid / rhabdoid tumor 6 | 4,971
adult high grade glioma 5 | 3,701
group 3 medulloblastoma 5 | 4,002
interstitial cystitis 5 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
invasive ductal carcinoma 5 | 2,867
primitive neuroectodermal tumor 5 | 2,957
Astrocytoma, Pilocytic 4 | 3,006
Pick disease 4 | 1,856
Rheumatoid arthritis 4 | 1,156
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,204
pituitary cancer 4 | 1,915
progressive supranuclear palsy 4 | 656
tuberculosis 4 | 1,963
ulcerative colitis 4 | 1,765
Breast cancer 3 | 3,469
Leukemia, Myelocytic, Acute 3 | 120
Multiple myeloma 3 | 1,296
Schizophrenia 3 | 1,136
acute myeloid leukemia 3 | 760
astrocytoma 3 | 1,113
gastric carcinoma 3 | 781
group 4 medulloblastoma 3 | 1,806
juvenile dermatomyositis 3 | 1,147
lung carcinoma 3 | 2,755
pancreatic cancer 3 | 2,322
subependymal giant cell astrocytoma 3 | 2,230
Alzheimer's disease 2 | 640
Anemia 2 | 353
Autosomal recessive nonsyndromic deafness 97 2 | 2
Carcinoma, Hepatocellular 2 | 217
Carcinoma, Squamous Cell 2 | 107
Copper-Overload Cirrhosis 2 | 11
Crohn's disease 2 | 311
Hepatitis, Chronic 2 | 23
Leukemia, Myeloid, Acute 2 | 105
Liver Cirrhosis, Experimental 2 | 733
Liver Neoplasms, Experimental 2 | 58
Liver cancer 2 | 589
Liver carcinoma 2 | 229
Liver disease 2 | 227
Mesothelioma, Malignant 2 | 103
Multiple Sclerosis 2 | 527
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neoplasm Invasiveness 2 | 151
Neoplasm Metastasis 2 | 160
Neuroblastoma 2 | 79
Nonsyndromic deafness 2 | 137
Pick's disease 2 | 15
Spinocerebellar ataxia type 2 2 | 23
Squamous cell carcinoma 2 | 125
breast carcinoma 2 | 1,589
dermatomyositis 2 | 941
diabetes mellitus 2 | 1,683
esophageal adenocarcinoma 2 | 696
hepatocellular carcinoma 2 | 536
mucosa-associated lymphoid tissue lymphoma 2 | 473
non primary Sjogren syndrome sicca 2 | 861
primary pancreatic ductal adenocarcinoma 2 | 1,071
Adenocarcinoma 1 | 116
B-Cell Lymphomas 1 | 11
Carcinoma of colon 1 | 32
Carcinoma, Non-Small-Cell Lung 1 | 97
Carcinoma, Renal Cell 1 | 121
Celiac disease 1 | 110
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Hermaphroditism 1 | 8
Hyperglycemia 1 | 134
Idiopathic scoliosis 1 | 31
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Insulin Resistance 1 | 70
Juvenile rheumatoid arthritis 1 | 110
Leukemia, Acute Myeloid 1 | 17
Lymphoma, B-Cell 1 | 6
Malocclusion 1 | 57
Mediastinal Neoplasms 1 | 2
Ovarian Neoplasms 1 | 96
Pain 1 | 102
Pancreatitis 1 | 118
Papillary renal cell carcinoma 1 | 9
Pulmonary Fibrosis 1 | 101
Renal Cell Carcinoma 1 | 211
Troyer syndrome 1 | 5
ovarian neoplasm 1 | 93

Tissue

Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192
Liver and Pancreas 19 | 16,750

Target Family

Non-IDG 12 | 12,091
Enzyme 7 | 4,145
Kinase 1 | 634

Reactome Pathway

Negative regulation of MET act... 20 | 20
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tchem Enzyme -1.72968 58.3 209
Endophilin-A1 SH3GL2 Tbio Non-IDG -1.79540 59.9 248
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.03962 9.87 97