Development Level

Tchem 10 | 1,598
Tbio 4 | 11,445
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
decreased circulating creatine... 1 | 4
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased circulating creatine... 1 | 5
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 979
small heart 1 | 10

Disease

Carcinoma 18 | 11,493
Schizophrenia 9 | 1,160
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
Alcoholic Intoxication, Chronic 6 | 289
Obesity 6 | 678
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
psoriasis 6 | 6,694
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
ovarian cancer 5 | 8,520
Attention deficit hyperactivity disorder 4 | 278
Bipolar Disorder 4 | 666
Depressive disorder 4 | 409
Epilepsy 4 | 792
Glaucoma 4 | 239
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
adult high grade glioma 4 | 3,801
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Binge eating disorder 3 | 3
Glycine encephalopathy 3 | 29
Hartnup disease 3 | 13
Hyperekplexia 3 | 16
Hypertension 3 | 396
Iminoglycinuria 3 | 4
Kidney cancer 3 | 2,613
Narcolepsy 3 | 72
Severe major depression with psychotic features 3 | 9
Unipolar Depression 3 | 250
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
Amphetamine-Related Disorders 2 | 74
Atopic dermatitis 2 | 952
Axial hypotonia 2 | 46
Choreatic disease 2 | 52
Cocaine Dependence 2 | 51
Cognitive delay 2 | 608
Cystinuria 2 | 18
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonia, Limb 2 | 9
Female stress incontinence 2 | 7
Gilles de la Tourette syndrome 2 | 47
Gingivitis 2 | 29
Global developmental delay 2 | 608
HYPERGLYCINURIA (disorder) 2 | 12
Hyperglycinuria 2 | 3
Hypertensive disease 2 | 292
Hypertensive disorder 2 | 56
Infantile onset 2 | 238
Kidney disease 2 | 430
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Mood Disorders 2 | 184
Mouth Infection Prevention 2 | 5
Muscle Hypertonia 2 | 88
Nerve Degeneration 2 | 121
Nervous System Diseases 2 | 53
Nicotine dependence 2 | 54
Oppositional defiant disorder 2 | 17
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Pellagra 2 | 26
Pick disease 2 | 1,894
Seasonal affective disorder 2 | 28
Seizures 2 | 596
Smoking cessation assistance 2 | 8
Substance abuse 2 | 59
Systemic primary carnitine deficiency disease 2 | 15
Toxic encephalopathy 2 | 141
Tremor 2 | 113
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
nasopharyngeal carcinoma 2 | 1,058
nervous system disorder 2 | 53
obsessive-compulsive disorder 2 | 61
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
Abnormal brain FDG positron emission tomography 1 | 9
Congenital hereditary endothelial dystrophy of cornea 1 | 8
Delirium 1 | 10
Generalized hypotonia 1 | 37
Hypernasal voice 1 | 39
Nasal voice 1 | 39
Vasomotor rhinitis 1 | 12

Tissue

Endocrine System 17 | 18,159
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Female tissues 15 | 17,400
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Liver and Pancreas 13 | 16,750
Respiratory system 12 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Transporter 18 | 473

Reactome Pathway

Na+/Cl- dependent neurotransmi... 18 | 18
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent proline transporter SLC6A7 Tchem Transporter -2.10260 134.1 45
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Sodium-dependent neutral amino acid transporter B(0)AT1 SLC6A19 Tchem Transporter -1.89653 74.4 32
Sodium- and chloride-dependent glycine transporter 1 SLC6A9 Tchem Transporter -1.00521 10.4 55
Sodium- and chloride-dependent GABA transporter 3 SLC6A11 Tbio Transporter -2.26927 175.1 75
Sodium- and chloride-dependent betaine transporter SLC6A12 Tchem Transporter -2.34582 212.0 104
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 Tchem Transporter -1.42715 25.8 76
Sodium-dependent noradrenaline transporter SLC6A2 Tclin Transporter -2.87529 687.5 105
Solute carrier family 22 member 1 SLC22A1 Tchem Transporter -2.16768 152.4 206
Sodium- and chloride-dependent GABA transporter 2 SLC6A13 Tchem Transporter -2.43015 259.2 51