Development Level

Tbio 28 | 11,445
Tclin 6 | 613
Tdark 2 | 6,588
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 4 | 99
RFA-RM-18-021 4 | 328

IMPC Phenotype

impaired glucose tolerance 2 | 75
short tibia 2 | 97
abnormal anxiety-related respo... 1 | 1
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta vasculature 1 | 2
abnormal radius morphology 1 | 8
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 55
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
respiratory system phenotype 1 | 2
small heart 1 | 10
small liver 1 | 8

Disease

Carcinoma 29 | 11,493
atypical teratoid / rhabdoid tumor 22 | 5,112
Astrocytoma, Pilocytic 19 | 3,081
glioblastoma 19 | 5,792
psoriasis 18 | 6,694
ependymoma 17 | 4,679
medulloblastoma, large-cell 17 | 6,241
osteosarcoma 17 | 7,950
ovarian cancer 16 | 8,520
adult high grade glioma 15 | 3,801
primitive neuroectodermal tumor 15 | 3,035
Kidney cancer 14 | 2,613
lung cancer 14 | 4,740
oligodendroglioma 13 | 2,850
Breast cancer 12 | 3,578
group 3 medulloblastoma 12 | 4,104
invasive ductal carcinoma 12 | 2,951
malignant mesothelioma 12 | 3,232
Bipolar Disorder 11 | 666
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
Schizophrenia 10 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung adenocarcinoma 10 | 2,716
Autosomal recessive predisposition 9 | 1,442
Pick disease 9 | 1,894
pancreatic cancer 9 | 2,398
subependymal giant cell astrocytoma 9 | 2,287
Epilepsy 8 | 792
Liver cancer 8 | 604
astrocytic glioma 8 | 2,597
lung carcinoma 8 | 2,843
Duchenne muscular dystrophy 7 | 601
Hirschsprung's disease 7 | 46
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 807
Alzheimer's disease 6 | 658
Hyperhidrosis disorder 6 | 81
Increased sweating 6 | 81
Liver Cirrhosis, Experimental 6 | 769
Myopia 6 | 176
Progressive disorder 6 | 142
Sweating 6 | 81
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
juvenile dermatomyositis 6 | 1,187
ulcerative colitis 6 | 1,819
Alport syndrome 5 | 21
Atopic dermatitis 5 | 952
Becker muscular dystrophy 5 | 191
Cataract 5 | 297
Down syndrome 5 | 499
Highly variable severity 5 | 157
Hypertensive disease 5 | 292
Lens Opacities 5 | 231
Major Depressive Disorder 5 | 301
Mildly increased creatine kinase 5 | 20
Nephrotic Syndrome 5 | 78
Parkinson's disease 5 | 392
Sensorineural Hearing Loss (disorder) 5 | 284
Skin cancer 5 | 469
Variable expressivity 5 | 157
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
dermatomyositis 5 | 966
medulloblastoma 5 | 720
non-small cell lung cancer 5 | 2,890
Abortion, Spontaneous 4 | 109
Angina Pectoris 4 | 32
Bethlem myopathy 4 | 6
Cardiovascular Abnormalities 4 | 31
Cardiovascular Diseases 4 | 59
Constipation 4 | 181
Creatine phosphokinase serum increased 4 | 110
Degenerative polyarthritis 4 | 115
Depressive disorder 4 | 409
Dyschezia 4 | 135
Electromyogram abnormal 4 | 49
Elevated creatine kinase 4 | 110
Hypertensive disorder 4 | 56
Increase in blood pressure 4 | 119
Kidney disease 4 | 430
Melanoma 4 | 711
Mood Disorders 4 | 184
Myopathy 4 | 185
Osteoarthritis 4 | 184
Proximal muscle weakness 4 | 47
Proximal neurogenic muscle weakness 4 | 47
Short stature 4 | 531
Spontaneous abortion 4 | 113
Unipolar Depression 4 | 250
Weight decreased 4 | 103
fibroadenoma 4 | 559
limb girdle muscular dystrophy 2A 4 | 213
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010

Tissue

Endocrine System 36 | 18,159
Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Female tissues 34 | 17,400
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Liver and Pancreas 32 | 16,750
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 25 | 12,091
Ion Channel 10 | 344
Enzyme 2 | 4,145

Reactome Pathway

NCAM1 interactions 37 | 37
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Alternative prion protein PRNP Tbio Non-IDG -3.45326 5611.1 0
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.80531 59.2 151
Contactin-2 CNTN2 Tbio Non-IDG -2.59791 404.0 198
Collagen alpha-6(VI) chain COL6A6 Tdark Non-IDG -0.48745 3.28 27
Persephin PSPN Tbio Non-IDG -1.41761 21.8 153