Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal cecum morphology 1 | 7
abnormal vibrissa morphology 1 | 25
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased eosinophil cell numb... 1 | 11
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

tuberculosis 9 | 2,010
lung carcinoma 8 | 2,843
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
cutaneous lupus erythematosus 6 | 1,057
diabetes mellitus 6 | 1,728
lung cancer 6 | 4,740
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
Malaria 5 | 160
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Allergic hypersensitivity disease 4 | 126
Asthma 4 | 385
Brain Injuries 4 | 65
Cancer 4 | 2,499
Pneumonia 4 | 174
Reperfusion Injury 4 | 86
Rheumatoid arthritis 4 | 1,191
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
osteosarcoma 4 | 7,950
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Arthritis 3 | 290
Cerebrovascular disease 3 | 238
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Eosinophilia 3 | 28
Hypersensitivity reaction type II disease 3 | 253
Hypertension 3 | 396
Hypertensive disease 3 | 292
Inflammation 3 | 120
Inflammatory bowel disease 3 | 151
Influenza 3 | 142
Keratitis 3 | 62
Liver Cirrhosis, Experimental 3 | 769
Meningitis 3 | 67
Obesity 3 | 678
Perinatal necrotizing enterocolitis 3 | 21
Peritonitis 3 | 43
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
periodontitis 3 | 293
Adverse reaction to drug 2 | 61
Arthritis, Rheumatoid 2 | 174
Atherosclerosis 2 | 291
Bipolar Disorder 2 | 666
Cholestasis 2 | 155
Cholestasis, Extrahepatic 2 | 25
Chronic obstructive pulmonary disease 2 | 184
Common cold 2 | 67
Dermatitis 2 | 157
Diarrhea 2 | 253
Drug-Related Side Effects and Adverse Reactions 2 | 62
Duchenne muscular dystrophy 2 | 601
Fatty liver disease 2 | 103
Gastritis 2 | 47
Heart disease 2 | 306
Human immunodeficiency virus infectious disease 2 | 138
Immune system cancer 2 | 140
Immunologic Deficiency Syndromes 2 | 113
Kidney disease 2 | 430
Leishmaniasis 2 | 47
Leptospirosis 2 | 18
Liver disease 2 | 237
Lymphoid leukemia 2 | 160
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 2 | 11
Mastitis 2 | 48
Multiple Sclerosis 2 | 540
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Otitis Media 2 | 52
Pelvic inflammatory disease 2 | 21
Salmonellosis 2 | 42
Tularemia 2 | 23
Vasculitis 2 | 80
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
chronic lymphosyte leukemia 2 | 204
dermatomyositis 2 | 966
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 9 | 12,091

Reactome Pathway

MyD88 deficiency (TLR2/4) 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Toll-like receptor 6 TLR6 Tbio Non-IDG -2.18033 129.1 692
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Monocyte differentiation antigen CD14 CD14 Tbio Non-IDG -1.99511 109.6 2307
Toll/interleukin-1 receptor domain-containing adapter protein TIRAP Tbio Non-IDG -1.96027 90.9 401
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289
Toll-like receptor 1 TLR1 Tbio Non-IDG -2.61529 374.7 516
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.50532 3420.9 1102