Development Level

Tbio 6 | 10,625
Tchem 4 | 1,890
Tclin 1 | 602

IMPC Phenotype

decreased body weight 1 | 174
decreased mean corpuscular vol... 1 | 50
increased CD4-positive, alpha ... 1 | 15
increased body weight 1 | 42

Disease

tuberculosis 10 | 1,563
lung carcinoma 9 | 2,844
ovarian cancer 8 | 8,491
cutaneous lupus erythematosus 7 | 1,056
glioblastoma 7 | 5,572
lung cancer 7 | 4,473
psoriasis 7 | 6,685
IGA Glomerulonephritis 6 | 454
malignant mesothelioma 6 | 3,163
Asthma 5 | 349
Cancer 5 | 2,346
Malaria 5 | 140
diabetes mellitus 5 | 1,663
medulloblastoma, large-cell 5 | 6,234
osteosarcoma 5 | 7,933
pilocytic astrocytoma 5 | 3,086
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 2,087
Breast cancer 4 | 3,098
Meningitis 4 | 46
Pneumonia 4 | 133
Prostatic Neoplasms 4 | 471
Reperfusion Injury 4 | 84
Rheumatoid Arthritis 4 | 1,170
cystic fibrosis 4 | 1,670
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
juvenile dermatomyositis 4 | 1,189
pediatric high grade glioma 4 | 2,712
Arthritis 3 | 248
Colorectal Neoplasms 3 | 217
Hypersensitivity reaction type II disease 3 | 235
Inflammation 3 | 109
Inflammatory bowel disease 3 | 142
Influenza 3 | 142
Keratitis 3 | 42
Obesity 3 | 616
Perinatal necrotizing enterocolitis 3 | 18
Peritonitis 3 | 37
adrenocortical carcinoma 3 | 1,427
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
non-small cell lung cancer 3 | 2,798
periodontitis 3 | 269
Allergic hypersensitivity disease 2 | 123
Aspergillosis 2 | 23
Atherosclerosis 2 | 275
Chorioamnionitis 2 | 15
Chronic obstructive pulmonary disease 2 | 147
Coronary artery disease 2 | 240
Dermatitis 2 | 141
Duchenne muscular dystrophy 2 | 602
Heart disease 2 | 279
Human immunodeficiency virus infectious disease 2 | 129
Invasive Pneumococcal Disease, Recurrent Isolated, 1 2 | 2
Kidney disease 2 | 397
Leishmaniasis 2 | 49
Leprosy 2 | 77
Leptospirosis 2 | 17
Liver disease 2 | 219
Lyme disease 2 | 23
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 2 | 12
Macroglobulinemia 2 | 17
Mastitis 2 | 48
Melioidosis 2 | 11
Multiple Sclerosis 2 | 498
Neoplasm Invasiveness 2 | 127
Neoplasm Metastasis 2 | 138
Otitis media 2 | 32
Pelvic inflammatory disease 2 | 21
Staphylococcal Infections 2 | 4
Tularemia 2 | 22
aldosterone-producing adenoma 2 | 664
astrocytoma 2 | 1,493
chronic lymphosyte leukemia 2 | 232
dermatomyositis 2 | 966
fibroadenoma 2 | 557
hepatocellular carcinoma 2 | 550
lung adenocarcinoma 2 | 2,714
mucosa-associated lymphoid tissue lymphoma 2 | 480
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
Age related macular degeneration 1 | 84
Brain disease 1 | 84
Carcinoma of colon 1 | 32
Common cold 1 | 63
Fatty Liver 1 | 48
Fatty liver disease 1 | 86
Keratoconjunctivitis sicca 1 | 19
Liver Cirrhosis 1 | 101
Neurogenic bowel 1 | 6
Non-alcoholic Fatty Liver Disease 1 | 40
Rhinitis 1 | 46
ovarian neoplasm 1 | 97
uncontrolled asthma 1 | 67

Tissue

Blood and immune system 11 | 17,994
Cardiovascular System 11 | 17,957
Digestive Tract 11 | 18,472
Endocrine System 11 | 18,511
Female tissues 11 | 18,646
Liver and Pancreas 11 | 18,135
Male tissues 11 | 17,968
Nervous System 11 | 18,560
Respiratory system 11 | 17,483
Skin and soft tissues 11 | 18,114
Urinary Tract 11 | 18,443

Target Family

Non-IDG 9 | 11,969
Kinase 2 | 634

Reactome Pathway

MyD88 deficiency (TLR2/4) 11 | 11
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.73333 490.7 314
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.47133 3173.5 946
Tyrosine-protein kinase BTK BTK Tclin Kinase -3.02467 1061.8 721
Toll/interleukin-1 receptor domain-containing adapter protein TIRAP Tbio Non-IDG -1.94511 85.7 369
Monocyte differentiation antigen CD14 CD14 Tbio Non-IDG -1.99328 102.0 1838
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.77330 6171.6 1142
Toll-like receptor 1 TLR1 Tbio Non-IDG -2.58297 353.3 448
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.22244 1606.1 561
Platelet glycoprotein 4 CD36 Tchem Non-IDG -2.61942 361.5 892
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.24767 182.4 530