Development Level

Tbio 6 | 11,445
Tdark 2 | 6,588

Disease

Carcinoma 7 | 11,493
Diastrophic dysplasia 7 | 21
Pendred Syndrome 7 | 22
psoriasis 5 | 6,694
Nonsyndromic deafness 4 | 142
Abdomen distended 3 | 43
Autosomal recessive predisposition 3 | 1,442
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
ovarian cancer 3 | 8,520
Abnormality of metabolism/homeostasis 2 | 134
Breast cancer 2 | 3,578
Diarrhea 2 | 253
Intestinal Obstruction 2 | 31
Kidney cancer 2 | 2,613
Muscle hypotonia 2 | 571
Pick disease 2 | 1,894
Polyhydramnios 2 | 108
Schizophrenia 2 | 1,160
Short stature 2 | 531
active ulcerative colitis 2 | 764
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormality of the clavicle 1 | 14
Abnormality of the metacarpal bones 1 | 17
Abnormality of the patella 1 | 2
Absent or minimally ossified vertebral bodies 1 | 3
Achondrogenesis 1 | 6
Achondroplasia 1 | 21
Athyreosis 1 | 4
Athyroidal hypothyroidism 1 | 5
Bartter disease 1 | 13
Bone Diseases, Developmental 1 | 27
Cardiovascular Abnormalities 1 | 31
Cochlear malformation 1 | 5
Colitis, Ulcerative 1 | 59
Compensated hypothyroidism 1 | 5
Compression of spinal cord 1 | 10
Congenital hypothyroidism 1 | 26
DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT 1 | 3
Edema 1 | 81
Endolymphatic hydrops 1 | 1
Enlarged vestibular aqueduct 1 | 10
Excess nuchal skin 1 | 30
Flat proximal femoral epiphyses 1 | 8
Flexion contracture of hip 1 | 10
Goiter 1 | 38
Graves' disease 1 | 24
HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS 1 | 4
Hearing Loss, Sensorineural 1 | 11
Hernia, Femoral 1 | 7
Hitchhiker thumb 1 | 3
Horizontal sacrum 1 | 3
Hyperactive renin-angiotensin system 1 | 8
Hypersomnia 1 | 8
Hypochloremia (disorder) 1 | 6
Hyponatremia 1 | 25
Hypoplastic cochlea 1 | 6
Hypoplastic finger 1 | 17
Hypoplastic ilia 1 | 12
Increased plasma renin activity 1 | 8
Irregular epiphyses 1 | 10
Kyphosis 1 | 5
Laryngotracheal stenosis 1 | 2
Lethal skeletal dysplasia 1 | 6
Metabolic alkalosis 1 | 4
Osteosclerosis 1 | 31
Pendred's syndrome 1 | 3
Platyspondyly 1 | 56
Proximally placed thumbs 1 | 17
Pseudoachondroplasia 1 | 14
Sandal gap 1 | 24
Serum chloride level decreased (finding) 1 | 6
Short finger 1 | 17
Short limb dwarfism recognizable at birth 1 | 9
Short tubular bones 1 | 22
Small hand 1 | 36
Small wings of the pelvic girdle 1 | 12
Spondyloepiphyseal dysplasia congenita 1 | 4
Spondyloepiphyseal dysplasia with congenital joint dislocations 1 | 13
Thyroid Agenesis 1 | 5
Thyroid Hypoplasia 1 | 4
Thyroid carcinoma 1 | 5
Vestibular dysfunction 1 | 7
autosomal recessive nonsyndromic deafness 4 1 | 6

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Nervous System 7 | 16,725

Target Family

Transporter 7 | 473
Ion Channel 1 | 344

Reactome Pathway

Multifunctional anion exchange... 8 | 8
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-independent sulfate anion transporter SLC26A11 Tdark Transporter -0.88219 7.87 8
Pendrin SLC26A4 Tbio Transporter -2.69164 501.3 100
Sulfate transporter SLC26A2 Tbio Transporter -2.46180 284.1 76
Solute carrier family 26 member 9 SLC26A9 Tbio Transporter -1.25858 20.1 28
Chloride anion exchanger SLC26A3 Tbio Transporter -2.83731 669.8 49
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.90119 75.2 94
Anion exchange transporter SLC26A7 Tbio Transporter -1.26445 19.4 41
Sodium-coupled monocarboxylate transporter 2 SLC5A12 Tdark Transporter -0.66161 4.97 10