Development Level

Tbio 20 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, complete... 3 | 979
decreased circulating glucose ... 2 | 126
hypoactivity 2 | 132
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
absent startle reflex 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating glycerol... 1 | 9
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
short tibia 1 | 97
shortened QT interval 1 | 4

Disease

ovarian cancer 14 | 8,520
lung cancer 13 | 4,740
osteosarcoma 12 | 7,950
medulloblastoma, large-cell 11 | 6,241
Carcinoma 10 | 11,493
Cancer 9 | 2,499
glioblastoma 7 | 5,792
Multiple myeloma 6 | 1,332
atypical teratoid / rhabdoid tumor 6 | 5,112
psoriasis 6 | 6,694
Neurodegenerative disease 5 | 414
non-small cell lung cancer 5 | 2,890
Breast cancer 4 | 3,578
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
Alzheimer's disease 3 | 658
Anemia 3 | 365
Carcinoma, Squamous Cell 3 | 110
Skin Neoplasms 3 | 69
Squamous cell carcinoma 3 | 129
Vascular disease 3 | 319
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Adult T-Cell Lymphoma/Leukemia 2 | 30
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Cardiomegaly 2 | 116
Chemical and Drug Induced Liver Injury 2 | 195
Decreased tendon reflex 2 | 122
Epilepsy 2 | 792
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gait, Drop Foot 2 | 24
Hepatomegaly 2 | 285
Leukemia-Lymphoma, Adult T-Cell 2 | 30
Macular degeneration 2 | 65
Major Depressive Disorder 2 | 301
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Nerve Degeneration 2 | 121
Optic Atrophy 2 | 242
Pain 2 | 103
Pick disease 2 | 1,894
Pick's disease 2 | 15
Renal Cell Carcinoma 2 | 214
Unipolar Depression 2 | 250
acute myeloid leukemia 2 | 783
hepatocellular carcinoma 2 | 547
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Abnormal lower motor neuron morphology 1 | 6
Behavioral variant of frontotemporal dementia 1 | 8
Cleft uvula 1 | 27
Compulsive hoarding 1 | 7
Cranial nerve palsies 1 | 11
Decreased visual acuity, slowly progressive 1 | 13
Developmental arithmetic disorder 1 | 8
Dysphasia 1 | 23
EMG positive sharp waves 1 | 2
EMG: myopathic abnormalities 1 | 22
EMG: myotonic discharges 1 | 2
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Fatigable weakness of respiratory muscles 1 | 28
Fatty replacement of skeletal muscle 1 | 3
Frontotemporal cerebral atrophy 1 | 8
Hyperorality 1 | 7
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Leri-Weill dyschondrosteosis 1 | 7
Limited shoulder movement 1 | 3
Limited wrist extension 1 | 2
Long bone fractures 1 | 2
Long tract signs 1 | 3
Mutism 1 | 17
NONAKA MYOPATHY 1 | 2
Noonan syndrome 1 | 34
Paraparesis 1 | 6
Posterior fossa compression syndrome 1 | 2
Reflex, Ankle, Absent 1 | 8
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Slow decrease in visual acuity 1 | 13
Submucous cleft of hard palate 1 | 11
Variation in muscle fiber size 1 | 16
Weakness of hip flexors 1 | 2
Xerostomia 1 | 42

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 20 | 12,091
Kinase 6 | 634
Enzyme 1 | 4,145

Reactome Pathway

Mitophagy 27 | 27
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -1.21206 16.0 151
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Mitochondrial import receptor subunit TOM70 TOMM70 Tbio Non-IDG -1.78206 61.0 172
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Mitochondrial import receptor subunit TOM6 homolog TOMM6 Tdark Non-IDG -0.60245 3.80 56
Mitochondrial import receptor subunit TOM5 homolog TOMM5 Tdark Non-IDG -0.94659 8.55 11
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
Serine/threonine-protein phosphatase PGAM5, mitochondrial PGAM5 Tbio Enzyme -1.40119 21.5 27