Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased food intake 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
preweaning lethality, complete... 1 | 979

Disease

medulloblastoma, large-cell 3 | 6,241
Carcinoma 2 | 11,493
adrenocortical carcinoma 2 | 1,428
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
primitive neuroectodermal tumor 2 | 3,035
Astrocytoma, Pilocytic 1 | 3,081
Brain cancer 1 | 30
Cancer 1 | 2,499
Cardiovascular system disease 1 | 246
Cavernous hemangioma 1 | 11
Chemical and Drug Induced Liver Injury 1 | 195
Cholesterol ester storage disease 1 | 6
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 15
Chromosome 4q21 deletion syndrome 1 | 6
Diaphyseal medullary stenosis with bone malignancy 1 | 1
Diaphyseal medullary stenosis with malignant fibrous histiocytoma 1 | 1
Glaucoma 1 | 239
Histidinemia 1 | 9
Liver Cirrhosis, Experimental 1 | 769
Lymphoid leukemia 1 | 160
Malignant glioma 1 | 26
Melanoma 1 | 711
Multiple myeloma 1 | 1,332
Nevus 1 | 19
Pick disease 1 | 1,894
Prostatic Neoplasms 1 | 495
Pulp degeneration 1 | 1
Schizophrenia 1 | 1,160
Type 2 diabetes mellitus 1 | 272
Visual agnosia 1 | 3
Wernicke encephalopathy 1 | 12
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
cystic fibrosis 1 | 1,696
ependymoma 1 | 4,679
gastric carcinoma 1 | 807
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

Reactome Pathway

Methionine salvage pathway 5 | 5
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylthioribose-1-phosphate isomerase MRI1 Tbio Enzyme -2.37285 221.6 146
Enolase-phosphatase E1 ENOPH1 Tbio Enzyme -0.98363 9.96 124
S-methyl-5'-thioadenosine phosphorylase MTAP Tchem Enzyme -2.24214 189.9 176
Aspartate aminotransferase, cytoplasmic GOT1 Tbio Enzyme -2.25904 173.1 355
Methylthioribulose-1-phosphate dehydratase APIP Tbio Enzyme -0.87551 9.29 210