Development Level

Tbio 19 | 11,445
Tchem 4 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

increased mean corpuscular vol... 2 | 92
thrombocytosis 2 | 27
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
corneal opacity 1 | 32
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased red blood cell distr... 1 | 41
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating phosphat... 1 | 26
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
narrow eye opening 1 | 12
preweaning lethality, complete... 1 | 979
vertebral fusion 1 | 23

Disease

Carcinoma 15 | 11,493
lung cancer 14 | 4,740
ovarian cancer 14 | 8,520
Breast cancer 12 | 3,578
Cancer 9 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
osteosarcoma 8 | 7,950
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
psoriasis 7 | 6,694
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
acute myeloid leukemia 5 | 783
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
non-small cell lung carcinoma 5 | 317
pancreatic cancer 5 | 2,398
Cleft Palate 4 | 271
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
gastric cancer 4 | 459
malignant mesothelioma 4 | 3,232
Anemia 3 | 365
Breast Neoplasms 3 | 445
Epilepsy 3 | 792
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Schizophrenia 3 | 1,160
Seizures 3 | 596
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
oligodendroglioma 3 | 2,850
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
Adenoid Cystic Carcinoma 2 | 99
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Blepharoptosis 2 | 231
Carcinoma, Adenoid Cystic 2 | 99
Congenital deafness 2 | 185
Connective tissue disease 2 | 62
Constipation 2 | 181
Deafness 2 | 198
Decreased projection of maxilla 2 | 66
Deep overbite 2 | 4
Deficiency of upper jaw bones 2 | 66
Down syndrome 2 | 499
Dyschezia 2 | 135
Failure to gain weight 2 | 365
Hearing Loss, Partial 2 | 185
Hereditary Breast and Ovarian Cancer Syndrome 2 | 14
Hypoplasia of the maxilla 2 | 66
Hypoplastic mandible condyle 2 | 275
Hypotrophic maxilla 2 | 66
Intellectual disability 2 | 1,016
Low set ears 2 | 181
Lupus erythematosus 2 | 57
Mandibular hypoplasia 2 | 275
Maxillary retrognathia 2 | 66
Melanoma 2 | 711
Micrognathism 2 | 275
Muscle hypotonia 2 | 571
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Obesity 2 | 678
Overbite 2 | 4
Pediatric failure to thrive 2 | 365
Peritonitis 2 | 43
Pick disease 2 | 1,894
Pick's disease 2 | 15
Posterior lingual occlusion of mandibular teeth 2 | 4
Prenatal onset 2 | 139
Prostate cancer 2 | 175
Retrusion of upper jaw bones 2 | 66
Thyroiditis 2 | 29
Uranostaphyloschisis 2 | 167
Ventricular Septal Defects 2 | 119
Waldenstrons macroglobulinemia 2 | 765
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 21 | 12,091
Enzyme 3 | 4,145
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

Reactome Pathway

Metalloprotease DUBs 27 | 27
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 1-A HIST1H2AA Tbio Non-IDG -0.84480 8.19 69
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.27041 18.5 133
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 16
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Histone H2A type 2-B HIST2H2AB Tdark Non-IDG -0.56848 3.28 49
Histone H2A type 1-C HIST1H2AC Tdark Non-IDG -0.15970 0.82 25