Development Level

Tbio 6 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 8 | 7,950
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Rheumatoid arthritis 3 | 1,191
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
ependymoma 3 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive nonsyndromic deafness 97 2 | 2
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Squamous Cell 2 | 110
Copper-Overload Cirrhosis 2 | 11
Hepatitis, Chronic 2 | 23
Kidney cancer 2 | 2,613
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver Neoplasms, Experimental 2 | 59
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Liver disease 2 | 237
Mesothelioma, Malignant 2 | 105
Multiple myeloma 2 | 1,332
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neuroblastoma 2 | 80
Nonsyndromic deafness 2 | 142
Schizophrenia 2 | 1,160
Squamous cell carcinoma 2 | 129
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
Adenocarcinoma 1 | 122
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Cardiomyopathies 1 | 110
Cognition Disorders 1 | 32
DiGeorge syndrome 1 | 47
ENSP00000256078 1 | 30
Enophthalmos 1 | 75
Esophageal Neoplasms 1 | 69
Hypertrophy of breast 1 | 17
Increased hepatocellular carcinoma risk 1 | 27
Keratoconus 1 | 113
Language Disorders 1 | 13
Large intestine cancer 1 | 126
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Liver Failure, Acute 1 | 29
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Myocardial Infarction 1 | 151
Ovarian Neoplasms 1 | 102
Pancreatitis 1 | 123
Papillary renal cell carcinoma 1 | 9
Parkinson Disease 1 | 64
Pointed chin 1 | 33
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Progressive relapsing multiple sclerosis 1 | 19
Pulmonary Fibrosis 1 | 106
Renal Cell Carcinoma 1 | 214
Skin cancer 1 | 469
Somatic mutation 1 | 61
Sunken eyes 1 | 63
Systemic lupus erythematosus 1 | 194
Tetralogy of Fallot 1 | 63
Thin upper lip vermilion 1 | 67
Vascular Diseases 1 | 16
Velocardiofacial syndrome 1 | 46
adrenocortical adenoma 1 | 131
hereditary spastic paraplegia 1 | 318
interstitial lung disease 1 | 298
non-small cell lung carcinoma 1 | 317
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

Reactome Pathway

MET receptor recycling 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Ras-related protein Rab-4B RAB4B Tbio Enzyme -0.64440 3.48 79
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Ras-related protein Rab-4A RAB4A Tbio Enzyme -2.20077 148.7 256
ADP-ribosylation factor-binding protein GGA3 GGA3 Tbio Non-IDG -1.64319 39.5 145
Hepatocyte growth factor HGF Tchem Enzyme -3.30841 2392.1 724
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Crk-like protein CRKL Tbio Non-IDG -2.20025 160.0 521
Adapter molecule crk CRK Tbio Non-IDG -2.55195 357.0 432