Development Level

Tbio 16 | 10,625
Tchem 2 | 1,890
Tclin 2 | 602

IMPC Phenotype

abnormal behavior 2 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal posture 1 | 5
abnormal startle reflex 1 | 14
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
hypoactivity 1 | 89
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

ovarian cancer 15 | 8,491
osteosarcoma 14 | 7,933
medulloblastoma, large-cell 12 | 6,234
Cancer 11 | 2,346
glioblastoma 11 | 5,572
psoriasis 10 | 6,685
atypical teratoid / rhabdoid tumor 9 | 4,369
primitive neuroectodermal tumor 9 | 3,031
lung cancer 7 | 4,473
non-small cell lung cancer 7 | 2,798
oligodendroglioma 6 | 2,849
Carcinoma 5 | 2,147
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
Breast cancer 4 | 3,098
Neoplasm Invasiveness 4 | 127
Pick disease 4 | 1,893
astrocytoma 4 | 1,493
hepatocellular carcinoma 4 | 550
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung carcinoma 4 | 2,844
malignant mesothelioma 4 | 3,163
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
tuberculosis 4 | 1,563
ulcerative colitis 4 | 2,087
Colonic Neoplasms 3 | 126
Kidney disease 3 | 397
Liver Neoplasms, Experimental 3 | 48
Mammary Neoplasms 3 | 410
Rheumatoid Arthritis 3 | 1,170
acute myeloid leukemia 3 | 785
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
medulloblastoma 3 | 1,524
ovarian neoplasm 3 | 97
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 686
Adenocarcinoma 2 | 115
Adenoma 2 | 165
Alzheimer's disease 2 | 644
Bladder Neoplasm 2 | 109
Carcinoma of colon 2 | 32
Colorectal Cancer 2 | 62
Colorectal Neoplasms 2 | 217
Endometrial cancer 2 | 32
Inflammatory bowel disease 2 | 142
Intestinal benign neoplasm 2 | 11
Leukemia, Myelocytic, Acute 2 | 113
Liver carcinoma 2 | 217
Liver disease 2 | 219
Lobular neoplasia 2 | 15
Lung Neoplasms 2 | 171
Multiple myeloma 2 | 1,327
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neoplasm Metastasis 2 | 138
Neoplastic Syndromes, Hereditary 2 | 48
Nerve Degeneration 2 | 73
Osteoporosis 2 | 259
Pancreatic Neoplasm 2 | 79
Pick's disease 2 | 14
Prostatic Neoplasms 2 | 471
Spinocerebellar ataxia type 2 2 | 19
Squamous cell carcinoma 2 | 96
Stomach Neoplasms 2 | 282
Stomach cancer 2 | 18
Vascular disease 2 | 281
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,189
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 788
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
Cardiomegaly 1 | 66
Colon Carcinoma 1 | 25
Developmental Disabilities 1 | 20
Enamel caries 1 | 8
Familial adenomatous polyposis 1 | 33
Gastritis 1 | 44
Growth Disorders 1 | 33
Intestinal Neoplasms 1 | 11
Juvenile Myelomonocytic Leukemia 1 | 21
Liver Cirrhosis 1 | 101
Lynch syndrome 1 | 35
Malignant tumor of prostate 1 | 26
Nephroblastoma 1 | 45
Pernicious anemia 1 | 10
Precancerous Conditions 1 | 69
Salivary Gland Neoplasms 1 | 45

Tissue

Blood and immune system 20 | 17,994
Cardiovascular System 20 | 17,957
Digestive Tract 20 | 18,472
Endocrine System 20 | 18,511
Female tissues 20 | 18,646
Liver and Pancreas 20 | 18,135
Male tissues 20 | 17,968
Nervous System 20 | 18,560
Respiratory system 20 | 17,483
Skin and soft tissues 20 | 18,114
Urinary Tract 20 | 18,443

Target Family

Non-IDG 14 | 11,969
Enzyme 4 | 4,146
Kinase 2 | 634

Reactome Pathway

Listeria monocytogenes entry i... 20 | 20
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Catenin delta-1 CTNND1 Tbio Non-IDG -2.35591 263.8 490
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -3.98540 8801.0 1257
Cadherin-1 CDH1 Tbio Non-IDG -3.81358 5832.3 1347
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.00519 933.5 424
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.10500 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.62947 56.7 150
Hepatocyte growth factor receptor MET Tclin Kinase -3.29136 1856.0 1530
E3 ubiquitin-protein ligase Hakai CBLL1 Tbio Enzyme -1.08560 11.8 139
Hepatocyte growth factor-regulated tyrosine kinase substrate HGS Tbio Enzyme -2.87633 704.3 332
Signal transducing adapter molecule 1 STAM Tbio Non-IDG -1.06047 12.6 232