Development Level

Tchem 5 | 1,598
Tbio 4 | 11,445

IMPC Phenotype

abnormal gait 1 | 69
decreased circulating magnesiu... 1 | 13
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 7 | 11,493
invasive ductal carcinoma 5 | 2,951
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
osteosarcoma 4 | 7,950
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Renal Cell Carcinoma 3 | 214
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Brain Ischemia 2 | 110
Edema 2 | 81
Melanoma 2 | 711
Myocardial Reperfusion Injury 2 | 37
Nervous System Diseases 2 | 53
Parkinson's disease 2 | 392
Peripheral Nervous System Diseases 2 | 52
Peripheral Neuropathy 2 | 134
Retinal Detachment 2 | 51
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
X-linked cerebral adrenoleukodystrophy 2 | 116
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
nervous system disorder 2 | 53
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
Adenocarcinoma 1 | 122
Adenoid Cystic Carcinoma 1 | 99
Alzheimer Disease 1 | 83
Amyotrophic lateral sclerosis 1 | 451
Brain disease 1 | 96
COPD 1 | 118
Calcinosis 1 | 70
Carcinoma of colon 1 | 32
Carcinoma, Adenoid Cystic 1 | 99
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Carcinoma, Transitional Cell 1 | 32
Celiac disease 1 | 116
Cerebral Hemorrhage 1 | 42
Colorectal Neoplasms 1 | 243
Dementia 1 | 175
Diabetes Mellitus, Experimental 1 | 108
Diabetic Angiopathies 1 | 16
Endometrial cancer 1 | 311
Esophageal Neoplasms 1 | 69
Eye disease 1 | 62
Gaucher disease type 1 1 | 180
Heart valve disease 1 | 39
Huntington's disease 1 | 76
Hyperglycemia 1 | 137
Infertility 1 | 188
Inflammatory bowel disease 1 | 151
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver cancer 1 | 604
Liver disease 1 | 237
Lung Neoplasms 1 | 232
Lung disease 1 | 142
MYELODYSPLASTIC SYNDROME 1 | 53
Malignant Squamous Cell Neoplasm 1 | 17
Myelodysplastic Syndromes 1 | 26
Myocardial Infarction 1 | 151
Myopathy 1 | 185
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Neuropathy 1 | 261
Pancreatitis 1 | 123
Prader-Willi syndrome 1 | 48
Reperfusion Injury 1 | 86
Salivary Gland Neoplasms 1 | 46
Seborrheic keratosis 1 | 8
Skin cancer 1 | 469
Squamous cell carcinoma 1 | 129
Status Epilepticus 1 | 98
Stomach Neoplasms 1 | 300
Subarachnoid Hemorrhage 1 | 7
Type 1 diabetes mellitus 6 1 | 2
atypical teratoid/rhabdoid tumor 1 | 357
facioscapulohumeral dystrophy 1 | 288
substance-related disorder 1 | 162
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Liver and Pancreas 8 | 16,750
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 4 | 12,091
Kinase 3 | 634
Enzyme 2 | 4,145

Reactome Pathway

Ligand-independent caspase act... 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
Death-associated protein kinase 2 DAPK2 Tchem Kinase -1.39206 28.7 440
Death-associated protein kinase 3 DAPK3 Tchem Kinase -1.64668 50.7 291
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Death-associated protein kinase 1 DAPK1 Tchem Kinase -2.34153 226.1 276
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Netrin receptor UNC5A UNC5A Tbio Non-IDG -1.25948 14.2 74
Netrin receptor UNC5B UNC5B Tbio Non-IDG -1.72310 48.3 115
Netrin receptor DCC DCC Tbio Non-IDG -2.05574 103.6 222