Development Level

Tbio 103 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal spleen morphology 1 | 55
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prolonged QT interval 1 | 38

Disease

ovarian cancer 47 | 8,520
lung cancer 35 | 4,740
Multiple myeloma 34 | 1,332
diabetes mellitus 30 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
medulloblastoma, large-cell 28 | 6,241
Diamond-Blackfan anemia 25 | 31
Carcinoma 23 | 11,493
osteosarcoma 22 | 7,950
Waldenstrons macroglobulinemia 18 | 765
psoriasis 16 | 6,694
acute quadriplegic myopathy 15 | 1,158
atypical teratoid / rhabdoid tumor 15 | 5,112
glioblastoma 15 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
sonic hedgehog group medulloblastoma 14 | 467
Abnormality of the urinary system 13 | 21
Anemia 13 | 365
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Breast cancer 13 | 3,578
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Cleft Palate 13 | 271
Conduction disorder of the heart 13 | 79
Delayed Puberty 13 | 97
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
Uranostaphyloschisis 13 | 167
genital abnormal 13 | 17
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
reproductive system abnormality 13 | 17
oligodendroglioma 12 | 2,850
Cancer 10 | 2,499
cystic fibrosis 10 | 1,696
malignant mesothelioma 10 | 3,232
Breast Neoplasms 8 | 445
Disease Progression 8 | 136
Mammary Neoplasms 8 | 425
Stomach Neoplasms 8 | 300
acute myeloid leukemia 8 | 783
astrocytoma 8 | 1,146
subependymal giant cell astrocytoma 8 | 2,287
colon cancer 7 | 1,478
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
mucosa-associated lymphoid tissue lymphoma 7 | 484
Adenocarcinoma of lung 6 | 142
Disease Models, Animal 6 | 155
adult high grade glioma 6 | 3,801
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Duchenne muscular dystrophy 5 | 601
Prostatic Neoplasms 5 | 495
Reticulocytopenia 5 | 10
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Hereditary spherocytosis type 4 4 | 18
Infantile onset 4 | 238
Parkinson Disease 4 | 64
Retinitis pigmentosa 29 4 | 6
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
hereditary spastic paraplegia 4 | 318
inflammatory breast cancer 4 | 286
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Amyotrophic lateral sclerosis 3 | 451
Animal Mammary Neoplasms 3 | 136
Cardiovascular system disease 3 | 246
Elevated red cell adenosine deaminase activity 3 | 3
Hypoplastic mandible condyle 3 | 275
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Mandibular hypoplasia 3 | 275
Mean cell volume increased 3 | 5
Micrognathism 3 | 275
Neoplasm Invasiveness 3 | 161
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Pure red-cell aplasia 3 | 4
Retinitis pigmentosa 49 3 | 14
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Shwachman-Diamond syndrome 3 | 17
Spinocerebellar ataxia type 2 3 | 23
Triphalangeal thumb 3 | 9
Ventricular Septal Defects 3 | 119
Weight Gain 3 | 100
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966

Tissue

Endocrine System 111 | 18,159
Blood and immune system 110 | 16,909
Digestive Tract 110 | 17,369
Male tissues 110 | 17,142
Skin and soft tissues 110 | 17,230
Cardiovascular System 109 | 15,192
Female tissues 109 | 17,400
Liver and Pancreas 109 | 16,750
Nervous System 109 | 16,725
Respiratory system 109 | 16,393
Urinary Tract 109 | 16,678

Target Family

Non-IDG 112 | 12,091

Reactome Pathway

L13a-mediated translational si... 112 | 112
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
60S ribosomal protein L35 RPL35 Tbio Non-IDG -1.30696 19.1 124
60S ribosomal protein L10 RPL10 Tbio Non-IDG -0.94919 8.10 191
60S ribosomal protein L26-like 1 RPL26L1 Tdark Non-IDG 0.30 0.50 77
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.64278 64.4 67
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.92202 82.6 72