Development Level

Tbio 100 | 10,625
Tchem 7 | 1,890
Tdark 6 | 7,003

IMPC Phenotype

preweaning lethality, complete... 2 | 633
abnormal coat appearance 1 | 25
abnormal spleen morphology 1 | 36
abnormal thoracic vertebrae mo... 1 | 16
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
increased exploration in new e... 1 | 56
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 48 | 8,491
lung cancer 36 | 4,473
Multiple myeloma 34 | 1,327
diabetes mellitus 30 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,289
medulloblastoma, large-cell 28 | 6,234
Diamond-Blackfan anemia 24 | 30
osteosarcoma 22 | 7,933
sonic hedgehog group medulloblastoma 20 | 1,482
Waldenstrons macroglobulinemia 18 | 764
psoriasis 17 | 6,685
acute quadriplegic myopathy 15 | 1,157
atypical teratoid / rhabdoid tumor 14 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
Anemia, Diamond-Blackfan 13 | 15
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
glioblastoma 12 | 5,572
oligodendroglioma 12 | 2,849
Breast cancer 10 | 3,098
Cancer 10 | 2,346
cystic fibrosis 10 | 1,670
malignant mesothelioma 10 | 3,163
Disease Progression 8 | 125
Mammary Neoplasms 8 | 410
Stomach Neoplasms 8 | 282
acute myeloid leukemia 8 | 785
astrocytoma 8 | 1,493
group 3 medulloblastoma 8 | 2,254
subependymal giant cell astrocytoma 8 | 2,287
Anemia 7 | 252
colon cancer 7 | 1,475
inflammatory breast cancer 7 | 404
invasive ductal carcinoma 7 | 2,950
lung adenocarcinoma 7 | 2,714
mucosa-associated lymphoid tissue lymphoma 7 | 480
primitive neuroectodermal tumor 6 | 3,031
Duchenne muscular dystrophy 5 | 602
Prostatic Neoplasms 5 | 471
adult high grade glioma 5 | 2,148
glioblastoma multiforme 5 | 347
non-small cell lung cancer 5 | 2,798
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
Parkinson Disease 4 | 105
astrocytic glioma 4 | 2,241
ependymoma 4 | 2,514
hereditary spastic paraplegia 4 | 313
juvenile dermatomyositis 4 | 1,189
primary pancreatic ductal adenocarcinoma 4 | 1,271
Amyotrophic Lateral Sclerosis 3 | 432
Animal Mammary Neoplasms 3 | 135
Irregular astigmatism 3 | 11
Mammary Neoplasms, Experimental 3 | 149
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 334
Pure red-cell aplasia 3 | 4
Rheumatoid Arthritis 3 | 1,170
Weight Gain 3 | 87
atypical teratoid/rhabdoid tumor 3 | 1,095
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 966
Anoxia 2 | 33
Babesiosis 2 | 13
Bowen-Conradi syndrome 2 | 16
Brucellosis 2 | 24
Carcinoma 2 | 2,147
Diamond-Blackfan Anemia With Microtia And Cleft Palate 2 | 3
HIV Infections 2 | 99
Lacrimal gland carcinoma 2 | 5
Liver carcinoma 2 | 217
Lymphoid leukemia 2 | 69
Mesenchymal chondrosarcoma 2 | 4
Neoplasm Invasiveness 2 | 127
Neoplasm Metastasis 2 | 138
Osteoporosis 2 | 259
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2 | 18
Primary biliary cirrhosis 2 | 45
Renal Cell Carcinoma 2 | 199
Shwachman-Diamond syndrome 2 | 16
Spinocerebellar ataxia type 2 2 | 19
Spondylolysis 2 | 9
Spondylosis 2 | 13
Theileriasis 2 | 13
Treacher Collins syndrome 2 | 29
Turner syndrome 2 | 31
Tyrosinemia type I 2 | 4
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
fascioscapulohumeral muscular dystrophy 2 | 100
gastric carcinoma 2 | 832
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
posterior fossa group A ependymoma 2 | 1,511
relapsing-remitting multiple sclerosis 2 | 18
spina bifida 2 | 1,064
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 113 | 17,994
Cardiovascular System 113 | 17,957
Digestive Tract 113 | 18,472
Endocrine System 113 | 18,511
Female tissues 113 | 18,646
Liver and Pancreas 113 | 18,135
Male tissues 113 | 17,968
Nervous System 113 | 18,560
Respiratory system 113 | 17,483
Urinary Tract 113 | 18,443
Skin and soft tissues 111 | 18,114

Target Family

Non-IDG 113 | 11,969

Reactome Pathway

L13a-mediated translational si... 113 | 113
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.12258 1305.7 243
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.62587 63.2 46
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.83618 67.7 104
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39373 24.2 45
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.89981 78.2 62
60S acidic ribosomal protein P1 RPLP1 Tbio Non-IDG -1.22833 29.8 76
60S acidic ribosomal protein P2 RPLP2 Tbio Non-IDG -2.23919 29.8 129
60S acidic ribosomal protein P0 RPLP0 Tbio Non-IDG -1.62553 58.5 171
60S ribosomal protein L9 RPL9 Tbio Non-IDG -1.87874 74.6 158
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.21018 16.2 189