Development Level

Tbio 32 | 10,625
Tchem 7 | 1,890
Tdark 4 | 7,003

IMPC Term

embryonic lethality prior to t... 7 | 187
preweaning lethality, complete... 6 | 633
embryonic lethality prior to o... 5 | 148
decreased mean corpuscular vol... 3 | 50
decreased total body fat amoun... 3 | 186
decreased hemoglobin content 2 | 53
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular hem... 2 | 19
hypoactivity 2 | 89
short tibia 2 | 82
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
long tibia 1 | 13
small adrenal glands 1 | 15
small lymph nodes 1 | 1
thrombocytosis 1 | 23

Disease

ovarian cancer 23 | 8,484
psoriasis 22 | 6,685
medulloblastoma, large-cell 21 | 6,234
osteosarcoma 17 | 7,933
glioblastoma 16 | 5,572
lung carcinoma 16 | 2,844
atypical teratoid / rhabdoid tumor 13 | 4,369
primitive neuroectodermal tumor 13 | 3,031
Pick disease 12 | 1,893
ependymoma 12 | 2,514
oligodendroglioma 12 | 2,849
pilocytic astrocytoma 12 | 3,086
subependymal giant cell astrocytoma 12 | 2,287
Anemia 10 | 252
Breast cancer 10 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
lung cancer 10 | 4,466
non-small cell lung cancer 10 | 2,798
adult high grade glioma 9 | 2,148
astrocytic glioma 9 | 2,241
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,713
malignant mesothelioma 9 | 3,162
pancreatic cancer 9 | 2,300
pediatric high grade glioma 9 | 2,712
pituitary cancer 9 | 1,972
Hemochromatosis 8 | 55
Multiple myeloma 7 | 1,327
astrocytoma 7 | 1,493
cystic fibrosis 7 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Aceruloplasminemia 6 | 17
Cancer 6 | 2,346
adrenocortical carcinoma 6 | 1,427
diabetes mellitus 6 | 1,663
group 3 medulloblastoma 6 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
medulloblastoma 6 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
tuberculosis 6 | 1,557
ulcerative colitis 6 | 2,087
Alzheimer's disease 5 | 644
Kidney disease 5 | 396
Obesity 5 | 616
Osteopetrosis 5 | 40
Parkinson's disease 5 | 364
breast carcinoma 5 | 1,614
hepatocellular carcinoma 5 | 532
nasopharyngeal carcinoma 5 | 1,056
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
Inflammation 4 | 109
Iron Metabolism Disorders 4 | 5
Iron Overload 4 | 5
Neoplasm Invasiveness 4 | 127
Neurodegenerative disease 4 | 383
Rheumatoid Arthritis 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,056
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,875
interstitial cystitis 4 | 2,299
posterior fossa group A ependymoma 4 | 1,511
Atopic dermatitis 3 | 944
Atransferrinemia 3 | 8
Autistic Disorder 3 | 320
Contact Dermatitis 3 | 80
Cutis laxa 3 | 28
Drug-Induced Liver Injury 3 | 118
Duchenne muscular dystrophy 3 | 602
Heart disease 3 | 279
Hepatitis 3 | 61
IGA Glomerulonephritis 3 | 454
Iron deficiency anemia 3 | 6
Liver disease 3 | 219
Liver neoplasms 3 | 109
Malaria 3 | 140
Mammary Neoplasms 3 | 410
Vascular disease 3 | 281
colon cancer 3 | 1,475
dermatomyositis 3 | 933
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
inflammatory breast cancer 3 | 404
mucosa-associated lymphoid tissue lymphoma 3 | 480
pancreatic carcinoma 3 | 567
tuberculosis and treatment for 6 months 3 | 686
Arthritis 2 | 248
Down syndrome 2 | 548
Endometriosis 2 | 535
Hypersensitivity reaction type II disease 2 | 235
Myocardial Ischemia 2 | 169
aldosterone-producing adenoma 2 | 664
progressive supranuclear palsy 2 | 674
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 43 | 17,995
Cardiovascular System 43 | 17,958
Digestive Tract 43 | 18,473
Male tissues 43 | 17,969
Nervous System 43 | 18,561
Skin and soft tissues 43 | 18,115
Urinary Tract 43 | 18,444
Endocrine System 42 | 18,512
Female tissues 42 | 18,647
Liver and Pancreas 42 | 18,136
Respiratory system 42 | 17,484

Target Family

Enzyme 30 | 4,146
Non-IDG 7 | 11,971
Transporter 5 | 473
Ion Channel 1 | 341

Reactome Pathway

Iron uptake and transport 43 | 43
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Ferritin light chain FTL Tbio Non-IDG -2.37909 242.0 430
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.70084 48.5 131
V-type proton ATPase subunit e 2 ATP6V0E2 Tdark Enzyme 0.18 0.40 19
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -0.98803 10.3 111
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.50852 352.2 235