Development Level

Tbio 26 | 11,445
Tdark 11 | 6,588
Tclin 10 | 613
Tchem 6 | 1,598

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
abnormal seminal vesicle morph... 2 | 114
hyperactivity 2 | 148
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 39 | 11,493
medulloblastoma, large-cell 33 | 6,241
osteosarcoma 30 | 7,950
ovarian cancer 29 | 8,520
atypical teratoid / rhabdoid tumor 28 | 5,112
glioblastoma 26 | 5,792
psoriasis 25 | 6,694
adult high grade glioma 21 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Kidney cancer 19 | 2,613
ependymoma 19 | 4,679
primitive neuroectodermal tumor 19 | 3,035
group 3 medulloblastoma 18 | 4,104
lung cancer 17 | 4,740
Astrocytoma, Pilocytic 16 | 3,081
Breast cancer 16 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
oligodendroglioma 15 | 2,850
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
subependymal giant cell astrocytoma 13 | 2,287
Pick disease 12 | 1,894
lung carcinoma 12 | 2,843
Atrial Fibrillation 11 | 124
lung adenocarcinoma 11 | 2,716
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
pituitary cancer 11 | 1,972
interstitial cystitis 10 | 2,312
invasive ductal carcinoma 10 | 2,951
cystic fibrosis 9 | 1,696
ductal carcinoma in situ 9 | 1,745
Chronic heart failure 8 | 46
Congestive heart failure 8 | 113
Poisoning by digitalis glycoside 8 | 8
colon cancer 8 | 1,478
Hypertension 7 | 396
astrocytoma 7 | 1,146
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Bipolar Disorder 6 | 666
Epilepsy 6 | 792
group 4 medulloblastoma 6 | 1,855
Autosomal recessive predisposition 5 | 1,442
Cancer 5 | 2,499
Dementia 5 | 175
Hypertensive disease 5 | 292
Liver Cirrhosis, Experimental 5 | 769
Parkinson's disease 5 | 392
Seizures 5 | 596
Skin cancer 5 | 469
chronic rhinosinusitis 5 | 512
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pancreatic cancer 5 | 2,398
Adenoma 4 | 167
Anemia 4 | 365
Barrett's esophagus 4 | 182
Cerebellar Ataxia 4 | 304
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Dysarthria 4 | 192
Hailey-Hailey disease 4 | 6
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Osteoporosis 4 | 363
Poor school performance 4 | 645
Primary cutaneous amyloidosis 4 | 29
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
fibroadenoma 4 | 559
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
Allergic hypersensitivity disease 3 | 126
Arthritis 3 | 290
Asthma 3 | 385
Atopic dermatitis 3 | 952
Cocaine-Related Disorders 3 | 92
Coronary artery disease 3 | 268
Duchenne muscular dystrophy 3 | 601
Heart disease 3 | 306
Hepatomegaly 3 | 285
Mental Depression 3 | 333
Neurodegenerative disease 3 | 414
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
limb girdle muscular dystrophy 2A 3 | 213
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Digestive Tract 53 | 17,369
Endocrine System 53 | 18,159
Male tissues 53 | 17,142
Urinary Tract 53 | 16,678
Female tissues 52 | 17,400
Nervous System 52 | 16,725
Skin and soft tissues 51 | 17,230
Blood and immune system 50 | 16,909
Liver and Pancreas 50 | 16,750
Respiratory system 48 | 16,393
Cardiovascular System 45 | 15,192

Target Family

Transporter 36 | 473
Ion Channel 5 | 344
Non-IDG 5 | 12,091
Kinase 4 | 634
Enzyme 3 | 4,145

Reactome Pathway

Ion transport by P-type ATPase... 53 | 53
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
FXYD domain-containing ion transport regulator 3 FXYD3 Tbio Ion Channel -1.78093 58.4 76
Phospholipid-transporting ATPase IA ATP8A1 Tbio Transporter -1.56158 35.5 43
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Phospholipid-transporting ATPase IC ATP8B1 Tbio Transporter -2.47204 273.0 19
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.89031 7.06 189
Probable phospholipid-transporting ATPase VB ATP10B Tdark Transporter 0.48 0.35 10