Development Level

Tbio 3 | 11,445

Disease

Carcinoma 3 | 11,493
Fatigue 2 | 182
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Abnormality of lung morphology 1 | 1
Abnormality of the face 1 | 10
Acquired flat foot 1 | 72
Afro-textured hair 1 | 13
Aneurysm 1 | 7
Aneurysmal disease 1 | 6
Aortic Rupture 1 | 5
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Ataxia 1 | 15
Bladder Diverticulum 1 | 15
Broad clavicle 1 | 5
Broad ribs 1 | 12
Brucellosis 1 | 24
Buruli Ulcer 1 | 1
Carcinoma of bladder 1 | 2
Chronic diarrhea 1 | 29
Colitis, Ulcerative 1 | 59
Congenital hypoplasia of clavicle 1 | 18
Congenital pectus carinatum 1 | 52
Convex nasal ridge 1 | 37
Coughing 1 | 25
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Death in childhood 1 | 14
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Diffusely thickened skin 1 | 20
Disorder of face 1 | 10
Dry skin 1 | 75
Exostoses 1 | 11
Flatfoot 1 | 73
Food Hypersensitivity 1 | 3
Food allergy 1 | 8
Gait, Unsteady 1 | 29
Growth Disorders 1 | 35
Hair hypopigmentation 1 | 12
Hemolysis 1 | 6
Hemolysis (disorder) 1 | 6
Hepatitis, Chronic 1 | 23
Human immunodeficiency virus infectious disease 1 | 138
Hyperkyphosis 1 | 111
Hypertension, Pulmonary 1 | 37
Hypotension, Orthostatic 1 | 18
Hypothermia, natural 1 | 17
Inclusion body myositis 1 | 13
Inflammatory Bowel Diseases 1 | 35
Joint laxity 1 | 54
Juvenile rheumatoid arthritis 1 | 111
Kinky hair texture 1 | 13
Knee joint valgus deformity 1 | 56
Kyphosis deformity of spine 1 | 114
Leishmaniasis, Visceral 1 | 13
Leprosy 1 | 73
Limited elbow extension 1 | 19
Liver Neoplasms, Experimental 1 | 59
Mask-like facies 1 | 25
Meningitis, Meningococcal 1 | 3
Meningococcal meningitis 1 | 8
Menkes Kinky Hair Syndrome 1 | 2
Menkes disease 1 | 19
Metaphyseal spurs 1 | 2
Metaphyseal widening 1 | 22
Nappy hair texture 1 | 13
Narrow face 1 | 54
Neointima 1 | 5
Neurologic Manifestations 1 | 4
Pachyderma 1 | 20
Paralysed 1 | 42
Paralysis 1 | 9
Pelvic exostoses 1 | 3
Peripheral Neuropathy 1 | 134
Persistent open anterior fontanelle 1 | 3
Platyspondyly 1 | 56
Pleomorphic adenoma carcinoma 1 | 3
Prenatal Injuries 1 | 11
Pulmonary hypertension 1 | 85
Sialuria 1 | 9
Sinusitis 1 | 65
Soft skin 1 | 17
Stricture of artery 1 | 4
Thin face 1 | 54
Tonsillitis 1 | 16
Typhoid fever 1 | 22
Ureteral obstruction 1 | 33
Vascular System Injuries 1 | 9
Velvety skin 1 | 17
Venous insufficiency 1 | 9
Visceral leishmaniasis 1 | 14
Wilson disease 1 | 16
X- linked recessive 1 | 110
Xerosis 1 | 75

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 1 | 4,145
Non-IDG 1 | 12,091
Transporter 1 | 473

Reactome Pathway

Ion influx/efflux at host-path... 3 | 3
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
PDZ domain-containing protein 11 PDZD11 Tbio Non-IDG -2.04712 109.9 49