Development Level

Tbio 24 | 11,445
Tchem 18 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
absent testes 1 | 6
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
edema 1 | 59
enlarged lymph nodes 1 | 37
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

Cancer 32 | 2,499
ovarian cancer 28 | 8,520
osteosarcoma 27 | 7,950
medulloblastoma, large-cell 25 | 6,241
atypical teratoid / rhabdoid tumor 24 | 5,112
psoriasis 24 | 6,694
Carcinoma 22 | 11,493
glioblastoma 22 | 5,792
lung cancer 19 | 4,740
adult high grade glioma 18 | 3,801
ependymoma 17 | 4,679
Breast cancer 13 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
group 4 medulloblastoma 12 | 1,855
Astrocytoma, Pilocytic 11 | 3,081
Breast Neoplasms 11 | 445
lung adenocarcinoma 11 | 2,716
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
oligodendroglioma 10 | 2,850
Bipolar Disorder 9 | 666
Mammary Neoplasms 9 | 425
Schizophrenia 9 | 1,160
astrocytic glioma 9 | 2,597
hepatocellular carcinoma 9 | 547
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
primitive neuroectodermal tumor 9 | 3,035
Brain Ischemia 8 | 110
Vascular disease 8 | 319
diabetes mellitus 8 | 1,728
pancreatic cancer 8 | 2,398
Alzheimer's disease 7 | 658
Esophageal Neoplasms 7 | 69
Multiple myeloma 7 | 1,332
Myocardial Reperfusion Injury 7 | 37
Prostatic Neoplasms 7 | 495
Toxic encephalopathy 7 | 141
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
juvenile dermatomyositis 7 | 1,187
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Carcinoma, Hepatocellular 6 | 228
Diabetes Mellitus, Experimental 6 | 108
Diabetes Mellitus, Type 2 6 | 142
Kidney disease 6 | 430
Liver Neoplasms, Experimental 6 | 59
Liver carcinoma 6 | 240
Parkinson's disease 6 | 392
Stomach Neoplasms 6 | 300
acute myeloid leukemia 6 | 783
colon cancer 6 | 1,478
dermatomyositis 6 | 966
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Adenocarcinoma 5 | 122
Cell Transformation, Neoplastic 5 | 97
Cerebral Hemorrhage 5 | 42
Colonic Neoplasms 5 | 142
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Eye disease 5 | 62
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Lung Neoplasms 5 | 232
Lymphoid leukemia 5 | 160
Myocardial Infarction 5 | 151
Neoplastic Cell Transformation 5 | 89
Obesity 5 | 678
Reperfusion Injury 5 | 86
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Asthma 4 | 385
Atopic dermatitis 4 | 952
Chronic Lymphocytic Leukemia 4 | 262
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Epilepsy 4 | 792
Heart disease 4 | 306
Hypersensitivity reaction type II disease 4 | 253
Lymphoma 4 | 81
Melanoma 4 | 711
Neoplasm Metastasis 4 | 168
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Pick disease 4 | 1,894
Polycystic ovary syndrome 4 | 360
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
interstitial cystitis 4 | 2,312
pancreatic carcinoma 4 | 562
pituitary cancer 4 | 1,972

Tissue

Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 9 | 4,145
Transcription Factor 7 | 1,400
Kinase 3 | 634

Reactome Pathway

Intrinsic Pathway for Apoptosi... 44 | 44
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800