Development Level

Tbio 38 | 11,651
Tdark 5 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 3 | 239
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased circulating insulin ... 2 | 76
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased heart weight 2 | 62
increased lean body mass 2 | 172
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
increased anti-nuclear antigen... 1 | 19
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41

Disease

Carcinoma 31 | 11,493
ovarian cancer 30 | 8,520
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 16 | 6,241
psoriasis 14 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
Pick disease 11 | 1,894
glioblastoma 11 | 5,792
lung cancer 10 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
ependymoma 9 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Breast cancer 8 | 3,578
Kidney cancer 8 | 2,613
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
oligodendroglioma 8 | 2,850
Autosomal recessive predisposition 7 | 1,442
Congenital disorder of glycosylation 7 | 54
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
acute quadriplegic myopathy 6 | 1,158
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
primitive neuroectodermal tumor 6 | 3,035
non-small cell lung cancer 5 | 2,890
progressive supranuclear palsy 5 | 676
Astrocytoma, Pilocytic 4 | 3,081
Hypomyelinating leukodystrophy 6 4 | 26
tuberculosis and treatment for 6 months 4 | 409
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Global developmental delay 3 | 608
Heart disease 3 | 306
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Rheumatoid arthritis 3 | 1,191
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Alzheimer's disease 2 | 658
Autosomal dominant Robinow syndrome 2 2 | 22
Cancer 2 | 2,499
Dementia 2 | 175
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
Enterovirus Infections 2 | 6
Failure to gain weight 2 | 365
Histidinemia 2 | 9
Hypohidrosis 2 | 34
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Oculocerebrorenal syndrome 2 | 29
Pancreatic agenesis 2 | 17
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Progressive microcephaly 2 | 32
Reflex, Deep Tendon, Absent 2 | 92
Schizophrenia 2 | 1,160
Short neck 2 | 140
Tetanus 2 | 68
Vici syndrome 2 | 14
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
fiedler's myocarditis 2 | 5
hepatocellular carcinoma 2 | 547
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
Batten disease 1 | 13
Poor head control 1 | 14
Postnatal microcephaly 1 | 24
Retinitis pigmentosa 4 1 | 38

Tissue

Blood and immune system 43 | 16,909
Cardiovascular System 43 | 15,192
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678

Target Family

Non-IDG 31 | 12,091
Enzyme 12 | 4,145
Transcription Factor 1 | 1,400

Reactome Pathway

Intra-Golgi traffic 44 | 44
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127
BET1-like protein BET1L Tbio Non-IDG -0.07918 0.87 16
Conserved oligomeric Golgi complex subunit 5 COG5 Tbio Non-IDG -1.00301 10.4 26
Cytohesin-4 CYTH4 Tbio Non-IDG -1.03866 11.3 145
Conserved oligomeric Golgi complex subunit 2 COG2 Tbio Non-IDG -3.65712 4250.6 169
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.47467 28.0 125
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.60083 40.3 126
Synaptobrevin homolog YKT6 YKT6 Tbio Non-IDG -1.58852 39.0 37
Syntaxin-6 STX6 Tbio Non-IDG -1.77339 56.6 215
RAB6A-GEF complex partner protein 2 RGP1 Tbio Non-IDG 0.00000 87