Development Level

Tbio 38 | 10,625
Tdark 5 | 7,003
Tchem 2 | 1,890

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased lean body mass 2 | 107
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 73
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
decreased B cell number 1 | 30
decreased CD4-positive NK T ce... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased Ly6C-positive immatu... 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased marginal zone B cell... 1 | 1
decreased marginal zone precur... 1 | 1
decreased mature B cell number 1 | 25
decreased memory-marker CD4-po... 1 | 4
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
increased CD4-negative NK T ce... 1 | 4
increased CD4-positive, alpha ... 1 | 15
increased CD5-positive Ly6C-po... 1 | 4
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive T-hel... 1 | 2
increased Ly6C high monocyte n... 1 | 12
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating triglyce... 1 | 24
increased effector memory T-he... 1 | 5
increased exploration in new e... 1 | 56
increased follicular B cell nu... 1 | 1
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
limb grasping 1 | 35
shortened RR interval 1 | 19
straub tail 1 | 26

Disease

ovarian cancer 31 | 8,492
osteosarcoma 26 | 7,933
medulloblastoma, large-cell 16 | 6,234
psoriasis 14 | 6,685
atypical teratoid / rhabdoid tumor 13 | 4,369
Pick disease 11 | 1,893
glioblastoma 11 | 5,572
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung cancer 9 | 4,473
Breast cancer 8 | 3,099
diabetes mellitus 8 | 1,663
oligodendroglioma 8 | 2,849
ependymoma 7 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
malignant mesothelioma 7 | 3,163
Congenital disorder of glycosylation 6 | 53
acute quadriplegic myopathy 6 | 1,157
cystic fibrosis 6 | 1,670
invasive ductal carcinoma 6 | 2,950
lung carcinoma 6 | 2,844
primitive neuroectodermal tumor 6 | 3,031
astrocytic glioma 5 | 2,241
non-small cell lung cancer 5 | 2,798
progressive supranuclear palsy 5 | 674
tuberculosis and treatment for 6 months 5 | 686
Carcinoma 4 | 2,147
adult high grade glioma 4 | 2,148
astrocytoma 4 | 1,493
pediatric high grade glioma 4 | 2,712
pilocytic astrocytoma 4 | 3,086
Heart disease 3 | 279
Multiple myeloma 3 | 1,328
Rheumatoid Arthritis 3 | 1,171
acute myeloid leukemia 3 | 785
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,299
juvenile dermatomyositis 3 | 1,189
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,563
Alzheimer's disease 2 | 644
Bipolar Disorder 2 | 266
Cancer 2 | 2,346
Dementia 2 | 129
Gaucher disease type 3 2 | 76
Histidinemia 2 | 9
Hypohidrosis 2 | 13
IGA Glomerulonephritis 2 | 454
Oculocerebrorenal syndrome 2 | 24
Polycystic Ovary Syndrome 2 | 335
Schizophrenia 2 | 503
Tetanus 2 | 66
Vici syndrome 2 | 16
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 967
fiedler's myocarditis 2 | 5
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
medulloblastoma 2 | 1,524
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
sonic hedgehog group medulloblastoma 2 | 1,482
ulcerative colitis 2 | 2,087
Adenocarcinoma 1 | 115
Amnestic disorder 1 | 37
Ceroid lipofuscinosis, neuronal, 6 1 | 7
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 14
Common variable immunodeficiency 1 | 98
Congenital dyserythropoietic anemia 1 | 17
Early myoclonic encephalopathy 1 | 9
Enamel caries 1 | 8
Epithelial ovarian cancer 1 | 19
Fatty liver disease 1 | 86
Galactosemia 1 | 20
Intracranial aneurysm 1 | 20
Mastitis 1 | 48
Meniere's disease 1 | 25
Nasopharynx carcinoma 1 | 19
Opitz-GBBB syndrome 1 | 19
Osteoarthritis 1 | 96
Papillary thyroid carcinoma 1 | 37
Periventricular nodular heterotopia 1 | 26
Poor school performance 1 | 13
Precancerous Conditions 1 | 69
Pseudohypoparathyroidism 1 | 17
Rift Valley fever 1 | 13
Scoliosis 1 | 40
Severe congenital neutropenia 1 | 10
Spondylocostal dysostosis 1 | 12
Uterine fibroid 1 | 29
Velocardiofacial syndrome 1 | 45
substance-induced psychosis 1 | 7

Tissue

Blood and immune system 45 | 17,995
Digestive Tract 45 | 18,473
Endocrine System 45 | 18,512
Female tissues 45 | 18,647
Liver and Pancreas 45 | 18,136
Male tissues 45 | 17,969
Nervous System 45 | 18,561
Respiratory system 45 | 17,484
Urinary Tract 45 | 18,444
Cardiovascular System 44 | 17,958
Skin and soft tissues 44 | 18,115

Target Family

Non-IDG 31 | 11,969
Enzyme 13 | 4,146
Transcription Factor 1 | 1,400

Reactome Pathway

Intra-Golgi traffic 45 | 45
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.64671 44.7 112
Conserved oligomeric Golgi complex subunit 1 COG1 Tbio Non-IDG -1.66863 43.0 81
Cytohesin-4 CYTH4 Tbio Non-IDG -0.94527 9.29 127
Conserved oligomeric Golgi complex subunit 6 COG6 Tbio Non-IDG -1.58322 38.9 67
Conserved oligomeric Golgi complex subunit 2 COG2 Tbio Non-IDG -3.62231 3948.9 139
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
Ras-related protein Rab-39A RAB39A Tdark Enzyme -0.50515 3.49 65
Conserved oligomeric Golgi complex subunit 5 COG5 Tbio Non-IDG -0.92957 8.17 15
Ras-related protein Rab-36 RAB36 Tdark Enzyme -0.51688 3.97 84
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.38923 23.6 114