Development Level

Tbio 21 | 11,445
Tchem 13 | 1,598
Tclin 12 | 613

IMPC Phenotype

decreased blood urea nitrogen ... 2 | 51
decreased circulating creatini... 2 | 39
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
decreased T cell number 1 | 15
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

psoriasis 38 | 6,694
Cancer 37 | 2,499
lung cancer 32 | 4,740
Asthma 29 | 385
interstitial cystitis 29 | 2,312
tuberculosis 29 | 2,010
Arthritis 28 | 290
Multiple Sclerosis 27 | 540
lung carcinoma 27 | 2,843
Inflammatory bowel disease 25 | 151
Hypersensitivity reaction type II disease 24 | 253
glioblastoma 24 | 5,792
Lung disease 23 | 142
malignant mesothelioma 23 | 3,232
Dermatitis 22 | 157
Rheumatoid arthritis 22 | 1,191
ulcerative colitis 22 | 1,819
Pneumonia 21 | 174
ovarian cancer 21 | 8,520
Carcinoma 20 | 11,493
Kidney disease 20 | 430
cystic fibrosis 20 | 1,696
diabetes mellitus 20 | 1,728
cutaneous lupus erythematosus 19 | 1,057
pancreatic cancer 18 | 2,398
Astrocytoma, Pilocytic 17 | 3,081
Hypersensitivity 17 | 63
Inflammation 17 | 120
Liver disease 17 | 237
Pulmonary Fibrosis 17 | 106
adult high grade glioma 17 | 3,801
Allergic hypersensitivity disease 16 | 126
Atherosclerosis 16 | 291
Brain Ischemia 16 | 110
Schizophrenia 16 | 1,160
invasive ductal carcinoma 16 | 2,951
osteosarcoma 16 | 7,950
periodontitis 16 | 293
Malaria 15 | 160
Obesity 15 | 678
ependymoma 15 | 4,679
lung adenocarcinoma 15 | 2,716
Fever 14 | 138
Influenza 14 | 142
Reperfusion Injury 14 | 86
non-small cell lung cancer 14 | 2,890
Chemical and Drug Induced Liver Injury 13 | 195
Endometriosis 13 | 540
Hypereosinophilic syndrome 13 | 71
Liver Cirrhosis, Experimental 13 | 769
Anemia 12 | 365
Brain Injuries 12 | 65
Depressive disorder 12 | 409
Heart disease 12 | 306
Human immunodeficiency virus infectious disease 12 | 138
Leishmaniasis 12 | 47
Vascular disease 12 | 319
Vasculitis 12 | 80
sarcoidosis 12 | 370
subependymal giant cell astrocytoma 12 | 2,287
Allergic rhinitis 11 | 94
Arthritis, Rheumatoid 11 | 174
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
medulloblastoma, large-cell 11 | 6,241
Ankylosing spondylitis 10 | 140
Bipolar Disorder 10 | 666
Common cold 10 | 67
Coronary artery disease 10 | 268
Dermatologic disorders 10 | 93
Diarrhea 10 | 253
Glomerulonephritis 10 | 46
Hypertension 10 | 396
Meningitis 10 | 67
Mental Depression 10 | 333
Myocardial Ischemia 10 | 169
Skin Diseases 10 | 71
active ulcerative colitis 10 | 764
atypical teratoid / rhabdoid tumor 10 | 5,112
Acquired immunodeficiency syndrome 9 | 197
Colitis, Ulcerative 9 | 59
Dermatitis, Atopic 9 | 37
Eye disease 9 | 62
Hepatitis B 9 | 108
Hyperalgesia 9 | 83
Multiple myeloma 9 | 1,332
Myocardial Infarction 9 | 151
Pancreatitis 9 | 123
gastric carcinoma 9 | 807
head and neck cancer 9 | 271
hepatocellular carcinoma 9 | 547
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Cerebrovascular disease 8 | 238
Hepatitis, Autoimmune 8 | 17
Prostatic Neoplasms 8 | 495
mucosa-associated lymphoid tissue lymphoma 8 | 484
nasopharyngeal carcinoma 8 | 1,058
pituitary cancer 8 | 1,972

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Female tissues 45 | 17,400
Nervous System 43 | 16,725
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 36 | 12,091
GPCR 5 | 408
Enzyme 2 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

Reactome Pathway

Interleukin-10 signaling 46 | 46
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
C-C motif chemokine 3 CCL3 Tbio Non-IDG -3.16229 1382.6 677
Granulocyte colony-stimulating factor CSF3 Tbio Non-IDG -3.83212 6976.9 816
fMet-Leu-Phe receptor FPR1 Tchem GPCR -2.42752 255.1 277