Development Level

Tbio 149 | 11,445
Tchem 15 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
enlarged heart 2 | 210
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal anxiety-related respo... 1 | 1
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Cancer 101 | 2,499
Carcinoma 93 | 11,493
psoriasis 92 | 6,694
diabetes mellitus 81 | 1,728
Hypersensitivity reaction type II disease 71 | 253
Ankylosing spondylitis 70 | 140
Behcet's disease 70 | 89
Rheumatoid arthritis 70 | 1,191
Arthritis 65 | 290
Juvenile rheumatoid arthritis 64 | 111
Acquired immunodeficiency syndrome 59 | 197
Uveitis 59 | 103
Herpes zoster 57 | 68
dermatomyositis 55 | 966
Human immunodeficiency virus infectious disease 54 | 138
Psoriatic arthritis 52 | 86
Stevens-Johnson syndrome 52 | 92
osteosarcoma 52 | 7,950
Multiple Sclerosis 50 | 540
ovarian cancer 48 | 8,520
tuberculosis 47 | 2,010
glioblastoma 46 | 5,792
Dermatitis 40 | 157
lung cancer 40 | 4,740
Synovitis 37 | 78
lung carcinoma 36 | 2,843
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Astrocytoma, Pilocytic 33 | 3,081
adult high grade glioma 33 | 3,801
juvenile dermatomyositis 32 | 1,187
Liver disease 29 | 237
ependymoma 29 | 4,679
Hepatitis B 28 | 108
Anemia 26 | 365
cutaneous lupus erythematosus 26 | 1,057
malignant mesothelioma 26 | 3,232
Kidney disease 25 | 430
Leprosy 25 | 73
interstitial cystitis 25 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
subependymal giant cell astrocytoma 25 | 2,287
invasive ductal carcinoma 24 | 2,951
Primary immunodeficiency disease 23 | 54
Skin disease 23 | 66
Systemic lupus erythematosus 23 | 194
medulloblastoma, large-cell 23 | 6,241
pancreatic cancer 23 | 2,398
primary Sjogren syndrome 23 | 735
Hemochromatosis 22 | 54
atypical teratoid / rhabdoid tumor 22 | 5,112
Birdshot chorioretinopathy 21 | 23
Breast cancer 21 | 3,578
non-small cell lung cancer 21 | 2,890
sarcoidosis 21 | 370
active ulcerative colitis 20 | 764
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
cystic fibrosis 19 | 1,696
active Crohn's disease 18 | 922
breast carcinoma 18 | 1,638
pituitary cancer 18 | 1,972
ulcerative colitis 18 | 1,819
Narcolepsy 17 | 72
astrocytoma 17 | 1,146
Schizophrenia 16 | 1,160
Berylliosis 15 | 28
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Pre-Eclampsia 15 | 68
Diffuse cutaneous systemic sclerosis 14 | 17
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Psoriasis susceptibility 1 14 | 14
limited scleroderma 14 | 19
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Liver Cirrhosis, Experimental 13 | 769
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
esophageal adenocarcinoma 13 | 737
follicular lymphoma 13 | 20
group 3 medulloblastoma 13 | 4,104
Multiple myeloma 12 | 1,332
Atopic dermatitis 11 | 952
Duchenne muscular dystrophy 11 | 601
Influenza 11 | 142
lung adenocarcinoma 11 | 2,716
Asthma 10 | 385
Bipolar Disorder 10 | 666
Crohn's disease 10 | 321
Arthritis, Rheumatoid 9 | 174
Autosomal recessive predisposition 9 | 1,442
Microphthalmia with limb anomalies 9 | 40
Vasculitis 9 | 80
ductal carcinoma in situ 9 | 1,745
oligodendroglioma 9 | 2,850

Tissue

Digestive Tract 85 | 17,369
Female tissues 85 | 17,400
Liver and Pancreas 85 | 16,750
Endocrine System 84 | 18,159
Respiratory system 84 | 16,393
Skin and soft tissues 84 | 17,230
Urinary Tract 84 | 16,678
Blood and immune system 82 | 16,909
Male tissues 81 | 17,142
Nervous System 81 | 16,725
Cardiovascular System 79 | 15,192

Target Family

Non-IDG 132 | 12,091
Enzyme 19 | 4,145
Transcription Factor 11 | 1,400
Kinase 7 | 634
GPCR 1 | 408
TF/Epigenetic 1 | 38

Reactome Pathway

Interferon gamma signaling 171 | 171
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Guanylate-binding protein 7 GBP7 Tdark Non-IDG -0.45484 2.62 54
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.33923 241.0 400
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Tripartite motif-containing protein 26 TRIM26 Tbio Non-IDG -0.84838 7.42 107
Tripartite motif-containing protein 48 TRIM48 Tdark Non-IDG 0.70 0.26 85
HLA class I histocompatibility antigen, Cw-17 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Tripartite motif-containing protein 34 TRIM34 Tbio Non-IDG -1.20185 9.98 78