Development Level

Tbio 47 | 10,625
Tclin 5 | 602
Tchem 4 | 1,890
Tdark 4 | 7,003

IMPC Term

decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
increased lean body mass 4 | 107
abnormal bone structure 3 | 131
decreased body weight 3 | 174
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
tremors 3 | 34
abnormal heart left ventricle ... 2 | 20
abnormal locomotor activation 2 | 26
decreased circulating alkaline... 2 | 41
decreased exploration in new e... 2 | 9
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased pulmonary respirator... 2 | 4
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 52
increased circulating alkaline... 2 | 119
lethargy 2 | 5
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
small thymus 2 | 11
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal retina morphology 1 | 100
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating glycerol... 1 | 19
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
enlarged heart 1 | 111
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 40 | 6,234
glioblastoma 38 | 5,572
atypical teratoid / rhabdoid tumor 33 | 4,369
pilocytic astrocytoma 31 | 3,086
ovarian cancer 30 | 8,492
psoriasis 29 | 6,685
primitive neuroectodermal tumor 28 | 3,031
oligodendroglioma 26 | 2,849
pediatric high grade glioma 24 | 2,712
Autistic Disorder 22 | 320
ependymoma 22 | 2,514
osteosarcoma 22 | 7,933
Carcinoma 20 | 2,147
medulloblastoma 20 | 1,524
subependymal giant cell astrocytoma 20 | 2,287
Schizophrenia 19 | 503
astrocytic glioma 18 | 2,241
pituitary cancer 17 | 1,972
adult high grade glioma 16 | 2,148
lung carcinoma 16 | 2,844
Intellectual disability 15 | 573
Pick disease 15 | 1,893
lung cancer 15 | 4,473
malignant mesothelioma 14 | 3,163
Breast cancer 13 | 3,099
astrocytoma 13 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
posterior fossa group A ependymoma 12 | 1,511
invasive ductal carcinoma 11 | 2,950
Epilepsy 10 | 346
colon cancer 10 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
non-small cell lung cancer 10 | 2,798
sonic hedgehog group medulloblastoma 10 | 1,482
group 3 medulloblastoma 9 | 2,254
interstitial cystitis 9 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung adenocarcinoma 9 | 2,714
Parkinson's disease 8 | 364
Toxic encephalopathy 8 | 131
atypical teratoid/rhabdoid tumor 8 | 1,095
breast carcinoma 8 | 1,614
cystic fibrosis 8 | 1,670
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,875
posterior fossa group B ependymoma 8 | 1,530
Alzheimer's disease 7 | 644
Bipolar Disorder 7 | 266
Child Development Disorders, Pervasive 7 | 55
Asperger syndrome 6 | 35
pancreatic cancer 6 | 2,300
Alcoholism 5 | 14
Amyotrophic Lateral Sclerosis 5 | 432
Arteriosclerotic Parkinsonism 5 | 8
Extrapyramidal disease 5 | 8
Fragile X syndrome 5 | 31
General anesthesia 5 | 53
Influenza A Prevention 5 | 7
Influenza due to Influenza A virus 5 | 7
Local anesthesia 5 | 40
Obesity 5 | 616
Parkinsonism 5 | 19
Postencephalitic parkinsonism 5 | 12
active Crohn's disease 5 | 918
aldosterone-producing adenoma 5 | 664
non primary Sjogren syndrome sicca 5 | 840
Acquired metabolic disease 4 | 267
Alcohol dependence 4 | 107
Cocaine-Related Disorders 4 | 88
Huntington's disease 4 | 72
Melanoma 4 | 261
Nicotine dependence 4 | 53
Rheumatoid Arthritis 4 | 1,171
active ulcerative colitis 4 | 477
adrenocortical carcinoma 4 | 1,427
gastric carcinoma 4 | 832
nasopharyngeal carcinoma 4 | 1,056
primary pancreatic ductal adenocarcinoma 4 | 1,271
Attention deficit hyperactivity disorder 3 | 156
Cerebrovascular disease 3 | 231
Down syndrome 3 | 548
Endometriosis 3 | 535
Gaucher disease type 1 3 | 171
Gilles de la Tourette syndrome 3 | 47
Kidney cancer 3 | 121
Language Development Disorders 3 | 9
Moderate to Severe Alzheimer's Type Dementia 3 | 5
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 292
obsessive-compulsive disorder 3 | 34
Cancer 2 | 2,346
acute quadriplegic myopathy 2 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
fibroadenoma 2 | 557
nephrosclerosis 2 | 329
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
spina bifida 2 | 1,064
urothelial carcinoma 2 | 318

Tissue

Nervous System 59 | 18,561
Female tissues 58 | 18,647
Liver and Pancreas 58 | 18,136
Male tissues 58 | 17,969
Blood and immune system 57 | 17,995
Cardiovascular System 57 | 17,958
Digestive Tract 57 | 18,473
Endocrine System 57 | 18,512
Urinary Tract 57 | 18,444
Respiratory system 55 | 17,484
Skin and soft tissues 55 | 18,115

Target Family

Non-IDG 46 | 11,969
Enzyme 6 | 4,146
Ion Channel 5 | 341
GPCR 2 | 408
Kinase 1 | 634

Reactome Pathway

Interactions of neurexins and ... 60 | 60
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Band 4.1-like protein 5 EPB41L5 Tbio Non-IDG -1.29631 20.6 94
Amyloid beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.58931 44.9 114
Protein lin-7 homolog C LIN7C Tbio Non-IDG -1.00151 10.5 97
Synaptotagmin-2 SYT2 Tbio Non-IDG -1.91450 69.3 204
Disks large-associated protein 3 DLGAP3 Tbio Non-IDG -1.17468 15.9 82
Leucine-rich repeat transmembrane neuronal protein 1 LRRTM1 Tbio Non-IDG -1.22987 14.3 139
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.72363 48.4 144
Drebrin-like protein DBNL Tbio Non-IDG -1.16070 20.7 166
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.29937 33.0 142
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.19729 145.4 176